IKaposi sarcoma

I-Kaposi sarcoma (KS) sisifo somhlaza kwizicwili ezinxibelelanayo.

I-KS sisiphumo sosulelo kwi-gamma herpesvirus eyaziwa ngokuba yi-Kaposi sarcoma-enxulumene ne-herpesvirus (KSHV), okanye i-herpesvirus 8 (HHV8). Kwintsapho enye njenge-Epstein-Barr virus, ebangela i-mononucleosis.

I-KSHV idluliselwa ikakhulu ngamathe. Inokusasazeka ngokudibana ngokwesondo, utofelo-gazi, okanye ukufakelwa. Emva kokungena emzimbeni, intsholongwane inokuchaphazela iintlobo ezahlukeneyo zeeseli, ngakumbi iiseli ezihambisa imithambo yegazi kunye nemithambo ye-lymphatic. Njengazo zonke iherpesviruses, i-KSHV ihlala emzimbeni wakho ubomi bakho bonke. Ukuba amajoni akho omzimba aba buthathaka kwixa elizayo, le ntsholongwane inokuba nethuba lokuphinda iphinde isebenze, ibangele iimpawu.

Zine iindidi ze-KS esekwe kumaqela abantu abosulelekileyo:

• I-Classic KS: Ichaphazela ikakhulu amadoda amadala aseMpuma Yurophu, kuMbindi Mpuma, nakwinzala yeMeditera. Esi sifo sihlala sikhula kancinci.
• Ubhubhane (olunxulumene noGawulayo) KS: Uhlala uxhaphakile kubantu abanentsholongwane kaGawulayo nabane-AIDS.
• Indawo yokuhlala (yaseAfrika) KS: Ichaphazela ikakhulu abantu bayo yonke iminyaka e-Afrika.
• Inxulunyaniswa ne-Immunosuppression, okanye inxulumene nokufakwa kwenye into, i-KS: Ivela kubantu abaye batshintshwa amalungu kwaye ngamayeza athintela amajoni abo omzimba.

Amathumba (izilonda) zihlala zibonakala njengamaqhuma abomvu-bomvu okanye mfusa kulusu. Anombala obomvu-mfusa kuba zityebile kwimithambo yegazi.

Izilonda zinokuqala ukuvela kulo naliphi na ilungu lomzimba. Banokubonakala ngaphakathi emzimbeni. Izilonda ngaphakathi emzimbeni zisopha. Izilonda emiphungeni zinokubangela isikhohlela esinegazi okanye ukuphefumla okufutshane.

Umboneleli wezempilo uya kwenza uvavanyo lomzimba, egxile kwizilonda.

Olu vavanyo lulandelayo lunokwenziwa ukufumanisa i-KS:

• Bronchoscopy
• Ukuskena i-CT
• Endoscopy
• Ulusu lwe-biopsy

Indlela i-KS ephathwa ngayo ixhomekeke:

• Yimalini amajoni omzimba acinezelweyo (immunosuppression)
• Inani kunye nendawo yamathumba
• Iimpawu

Unyango lubandakanya:

• Unyango lwe-Antiviral ngokuchasene ne-HIV, kuba akukho lunyango oluthile lwe-HHV-8
• Ukudibanisa i-chemotherapy
• Ukubandezeleka kwezilonda
• Unyango ngemitha

Izilonda zingabuya emva konyango.

Ukunyanga i-KS akuphuculi amathuba okusinda kwi-HIV / AIDS uqobo. Imbonakalo ixhomekeke kwimeko yomzimba yokuzikhusela komzimba kunye nokuba ingakanani intsholongwane kagawulayo esegazini (umthwalo wentsholongwane). Ukuba i-HIV ilawulwa ngamayeza, izilonda ziya kuhlala zincipha zodwa.

Iingxaki zinokubandakanya:

• Isikhohlela (mhlawumbi sinegazi) kunye nokuphefumla kancinci ukuba isifo sisemiphungeni
• Ukudumba komlenze kunokuba buhlungu okanye kubangele usulelo ukuba isifo sikwi-lymph node zemilenze

Amathumba angabuya nasemva konyango. I-KS inokubulala umntu one-AIDS.

Uhlobo lobundlongondlongo lwe-KS engapheliyo lunokusasazeka ngokukhawuleza emathanjeni. Olunye uhlobo olufunyenwe kubantwana baseAfrika aluchaphazeli ulusu. Endaweni yoko, isasazeka kwii-lymph node kunye namalungu abalulekileyo, kwaye inokubulala ngokukhawuleza.

Izenzo ezikhuselekileyo zesondo zinokuthintela usulelo lwe-HIV. Oku kuthintela i-HIV / AIDS kunye neengxaki zayo, kubandakanya ne-KS.

I-KS phantse ayizange yenzeke kubantu abane-HIV / AIDS abagula zilawulwa kakuhle.

I-Kaparc’s sarcoma; Intsholongwane kagawulayo - Kaposi; UGawulayo - Kaposi

• I-Kaposi sarcoma -isilonda elunyaweni
• Kaposi sarcoma ngasemva
• IKaposi sarcoma -ukusondela
• I-sarcoma kaKaposi ethangeni
• I-Kaposi sarcoma - iperianal
• Kaposi sarcoma ngeenyawo

IKaye KM. I-Kaposi sarcoma enxulumene neherpesvirus (i-herpesvirus yabantu 8). Ku: Bennett JE, Dolin R, Blaser MJ, ii-eds. Mandell, Douglas, kunye neBennett's Principles and Practice of Infectious Diseases. Umhla we-9. IPhiladelphia, PA: Elsevier; 2020: isahluko 140.

UMerrick ST, uJones S, uGlesby MJ. Ukubonakaliswa kwenkqubo ye-HIV / AIDS. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 366.

Kwiwebhusayithi yeZiko loMhlaza weSizwe. Unyango lweKaposi sarcoma (PDQ) -uhlobo lobungcali kwezempilo. www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-unyango-pdq. Ukuhlaziywa ngoJulayi 27, 2018. Kufumaneka ngoFebruwari 18, 2021.