I-Tardive dyskinesia

I-Tardive dyskinesia (TD) sisifo esichaphazela iintshukumo ezingazibandakanyiyo. Ukulibazisa kuthetha ukulibaziseka kwaye idyskinesia ithetha ukuhamba okungaqhelekanga.

I-TD sisiphumo esibi esibi esenzeka xa usela amayeza abizwa ngokuba zii-neuroleptics. La machiza abizwa ngokuba zii-antipsychotic okanye i-tranquilizers eziphambili. Zisetyenziselwa ukunyanga iingxaki zengqondo.

I-TD ihlala isenzeka xa uthatha iyeza iinyanga ezininzi okanye iminyaka. Ngamanye amaxesha, kwenzeka emva kokuba ubathathe iiveki ezintandathu.

Amayeza aqhele ukubangela esi sifo kukudala i-antipsychotic, kubandakanya:

• Chlorpromazine
• Fluphenazine
• IHaloperidol
• IPerphenazine
• Iprochlorperazine
• Thioridazine
• Trifluoperazine

Ii-antipsychotic ezintsha zibonakala ngathi azinakubangela i-TD, kodwa azikho ngokupheleleyo ngaphandle komngcipheko.

Ezinye iziyobisi ezinokubangela i-TD zibandakanya:

• I-Metoclopramide (iphatha ingxaki yesisu ebizwa ngokuba yi-gastroparesis)
• Amayeza okulwa noxinzelelo njengeamitriptyline, fluoxetine, phenelzine, sertraline, trazodone
• Amayeza e-Anti-Parkinson afana nelevodopa
• Amayeza okubulala iintsholongwane afana ne-phenobarbital kunye ne-phenytoin

Iimpawu ze-TD zibandakanya ukungalawuleki kobuso kunye nomzimba onje:

• Ubuso obuncitshisiweyo (obuquka imisipha yobuso esezantsi)
• Ukuhamba kweminwe (ukudlala ipiyano)
• Ukunyikimisa okanye ukugungxula i-pelvis (njenge-duck-like gait)
• Umhlathi ujinga
• Ukuhlafuna okuphindayo
• Iliso elikhawulezayo eliqhwanyazayo
• Ulwimi luyatyhala
• Ukungazinzi

Xa i-TD ifunyenwe, umboneleli wezempilo uya kuthi uyeke iyeza kancinci okanye utshintshele kwelinye.

Ukuba i-TD ithambile okanye imodareyitha, amayeza ahlukeneyo anokuzanywa. Iyeza eligqiba idopamine, i-tetrabenazine lolona nyango lusebenzayo lwe-TD. Umboneleli wakho unokukuxelela ngakumbi malunga nezi.

Ukuba i-TD inzima kakhulu, inkqubo ebizwa ngokuba kukuvuselela ingqondo okunzulu i-DBS inokuzama. I-DBS isebenzisa isixhobo esibizwa ngokuba yi-neurostimulator ukuhambisa imiqondiso yombane kwiindawo zobuchopho ezilawula ukuhamba.

Ukuba ufunyaniswe kwangoko, i-TD inokubuyiselwa umva ngokuyeka iyeza elibangele iimpawu. Nokuba iyeza limisiwe, ukushukuma okungazibandakanyi kunokuba sisigxina, kwaye kwezinye iimeko, kunokuba kubi.

TD; Isifo seTardive; I-Orofacial dyskinesia; Ukuhamba okungafunekiyo -i-tardive dyskinesia; Iziyobisi ezichasayo - i-tardive dyskinesia; Iziyobisi Neuroleptic - tardive dyskinesia; Ischizophrenia - tardive dyskinesia

• Inkqubo ye-nervous central kunye ne-peripheral system

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