I-Sertoli-Leydig ithumba leseli

I-Sertoli-Leydig tumor tumor (i-SLCT) ngumhlaza onqabileyo wama-ovari. Iiseli zomhlaza zivelisa kwaye zikhulule ihomoni yesini eyindoda ebizwa ngokuba yi testosterone.

Oyena nobangela weli thumba akwaziwa. Utshintsho (uguquko) kwimfuza lunokudlala indima.

I-SLCT yenzeka rhoqo kwabasetyhini abancinci abaneminyaka engama-20 ukuya kwengama-30 ubudala. Kodwa ithumba inokwenzeka nakweyiphi na iminyaka.

Iiseli zeSertoli zihlala zikwindawo yamadlala okuzala (iimvavanyo). Bondla iiseli zedoda. Iiseli zeLeydig, ezibekwe nakwii-testes, zikhupha i-hormone yesini eyindoda.

Ezi seli zikwafumaneka kwii-ovari zowasetyhini, kwaye kwiimeko ezinqabileyo kakhulu zikhokelela kumhlaza. I-SLCT iqala kwizibeleko zabasetyhini, ubukhulu becala kwi-ovary enye. Iiseli zomhlaza zikhupha ihomoni yesini eyindoda. Ngenxa yoko, umfazi unokukhulisa iimpawu ezinje:

• Ilizwi elinzulu
• I-clitoris eyandisiweyo
• Iinwele zobuso
• Ukulahleka kubungakanani besifuba
• Ukuyeka ukuya exesheni

Ubuhlungu kwisisu esisezantsi (indawo ye-pelvic) lolunye uphawu. Kwenzeka ngenxa yokucinezeleka kwethumba kwizakhiwo ezikufuphi.

Umboneleli wezempilo uya kwenza uvavanyo lomzimba kunye novavanyo lwe-pelvic, kwaye abuze malunga neempawu.

Uvavanyo luya kuyalelwa ukuba luqwalasele amanqanaba amahomoni ababhinqileyo nabesilisa, kubandakanya ne testosterone.

I-ultrasound okanye i-CT scan iya kwenziwa ukuze ifumanise ukuba liphi na ithumba kunye nobukhulu kunye nobume bayo.

Utyando lwenziwa ukususa enye okanye zombini ii-ovari.

Ukuba i-tumor iqhubekile, i-chemotherapy okanye unyango lwe-radiation lunokwenziwa emva kotyando.

Unyango lwakwangoko lukhokelela kwisiphumo esihle. Iimpawu zowasetyhini zihlala zibuya emva kotyando. Kodwa iimpawu zamadoda zixazulula kancinci.

Ukufumana amathumba aphezulu kwinqanaba, umbono awuncinci.

Ithumba leSertoli-stromal; Arrhenoblastoma; Androblastoma; Umhlaza we-Ovarian - iSertoli-Leydig ithumba leseli

• Inkqubo yokuzala eyindoda

UPenick ER, uHamilton CA, uMaxwell GL, uMarcus CS. Iseli yentsholongwane, i-stromal, kunye namanye amathumba e-ovari. Ku: I-DiSaia PJ, iCreasman WT, iMannel RS, iMcMeekin DS, iMutch DG, ii-eds. Iiklinikhi zeGynecologic Oncology. Umhla we-9. IPhiladelphia, PA: Elsevier; I-2018: isahluko 12.

USmith RP. I-Sertoli-Leydig ithumba leseli (arrhenoblastoma). Ku: Smith RP, ed. I-Netter's Obstetrics kunye neGynecology. Ngomhla wesi-3. IPhiladelphia, PA: Elsevier; I-2018: isahluko 158.