Ithumba le-Hypothalamic

Ithumba le-hypothalamic kukukhula okungaqhelekanga kwi-hypothalamus gland, ebekwe kwingqondo.

Unobangela ngqo wamathumba e-hypothalamic awaziwa. Kungenzeka ukuba zibangelwe kukudityaniswa kwemfuza kunye nokusingqongileyo.

Kubantwana, uninzi lwamathumba e-hypothalamic zii-gliomas. I-Gliomas luhlobo oluqhelekileyo lwe-tumor ebangelwa kukukhula okungaqhelekanga kweeseli ze-glial, ezixhasa iiseli zemithambo-luvo. Iigliomas zinokwenzeka nakweyiphi na iminyaka. Bahlala beba ndlongondlongo kubantu abadala kunakubantwana.

Kubantu abadala, amathumba kwi-hypothalamus kunokwenzeka ukuba ngumhlaza osasazeke kwelinye ilungu.

Abantu abane-neurofibromatosis (imeko yelifa) basemngciphekweni owandayo wolu hlobo lwethumba. Abantu abaye bafumana unyango lwe-radiation basemngciphekweni omkhulu wokukhula kwamathumba ngokubanzi.

Ezi tumors zinokubangela uluhlu lweempawu:

• Iimvakalelo "eziphezulu"
• Ukusilela ukukhula (ukunqongophala kokukhula kwesiqhelo ebantwaneni)
• Intloko ebuhlungu
• Ukusebenza kakhulu
• Ukuphulukana namanqatha omzimba kunye nokutya (cachexia)

Ezi mpawu zihlala zibonwa kubantwana abanamathumba achaphazela icandelo langaphambili lehypothalamus.

Ezinye izicubu zinokubangela ukulahleka kombono. Ukuba amathumba athintela ukuhamba komgogodla, iintloko kunye nokulala kunokubangelwa kukuqokelelwa kolwelo kwingqondo (i-hydrocephalus).

Abanye abantu banokubanjwa ngenxa yamathumba obuchopho. Abanye abantu banokukhula kwinqanaba lokufikisa ngaphambi kotshintsho kwimisebenzi yebhinqa.

Umboneleli wakho wezempilo unokubona iimpawu zesisu se-hypothalamic ngexesha lokuhlolwa rhoqo. Uvavanyo lwengqondo kunye nenkqubo yemithambo-luvo, kubandakanya iimvavanyo zomsebenzi obonakalayo, zinokwenziwa. Uvavanyo lwegazi lokungalingani kwehomoni nako kunokuyalelwa.

Kuxhomekeka kwiziphumo zoviwo kunye novavanyo lwegazi, i-CT scan okanye iMRI scan inokumisela ukuba unethumba le-hypothalamic.

Uvavanyo lwentsimi ebonakalayo lunokwenziwa ukukhangela ukulahleka kombono kunye nokufumanisa ukuba imeko iyaphucuka okanye iya isiba mandundu.

Unyango luxhomekeke kwindlela eliqatha ngayo ithumba, nokuba iyi-glioma okanye olunye uhlobo lomhlaza. Unyango lunokubandakanya indibaniselwano yotyando, imitha kunye nekhemotherapy.

Unyango olukhethekileyo lwemitha lunokujolisa kwi-tumor. Zingasebenza njengokuhlinzwa, zinomngcipheko omncinci kwizicubu ezijikelezileyo. Ukudumba kobuchopho okubangelwa lithumba kunokufuna ukunyangwa nge-steroids.

Izidumba ze-Hypothalamic zinokuvelisa iihormoni okanye zichaphazele ukuveliswa kwehomoni, okukhokelela kukungalingani okunokufuna ukulungiswa. Ngamanye amaxesha, iihomoni zisenokufuna ukutshintshwa okanye ukunciphisa.

Unako ukunceda uxinzelelo lokugula ngokujoyina iqela lenkxaso apho amalungu abelana ngamava aqhelekileyo kunye neengxaki.

Imbonakalo ixhomekeke:

• Uhlobo lwethumba (glioma okanye olunye uhlobo)
• Indawo yethumba
• IBakala le-tumor
• Ubungakanani be-tumor
• Ubudala bakho kunye nempilo ngokubanzi

Ngokubanzi, iiglomas kubantu abadala zinoburharha ngakumbi kunabantwana kwaye zihlala zineziphumo ezibi. Izidumbu ezibangela ihydrocephalus zinokubangela ezinye iingxaki, kwaye zinokufuna utyando.

Iingxaki zotyando lobuchopho zinokubandakanya:

• Ukopha
• Umonakalo wobuchopho
• Ukufa (kunqabile)
• Usulelo

Ukuxhuzula kunokubangela ithumba okanye nayiphi na inkqubo yotyando ebuchotsheni.

IHydrocephalus inokwenzeka ngamanye amathumba kwaye inokufuna utyando okanye ipayinti ebekwe kwingqondo ukunciphisa uxinzelelo lomqolo womqolo.

Umngcipheko kunyango lwe-radiation lubandakanya ukonakala kweeseli zengqondo xa iiseli zethumba zitshatyalalisiwe.

Iziphumo eziqhelekileyo ezivela kwi-chemotherapy zibandakanya ukulahleka kwesidlo, isicupunu kunye nokuhlanza kunye nokudinwa.

Shayela umnikezeli wakho ukuba wena okanye umntwana wakho uvelisa naziphi na iimpawu zesisu se-hypothalamic. Ukuvavanywa rhoqo kwezonyango kunokufumana iimpawu zokuqala zengxaki, njengokufumana ubunzima ngokungaqhelekanga okanye ukufikisa ngaphambi kwexesha.

Hypothalamic glioma; Hypothalamus - ithumba

UGoodden J, uMallucci C. Optic wendlela ye-hypothalamic gliomas. Ku: Winn HR, ed. Ugqirha we-Youmans kunye no-Winn Neurological. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 207.

IWeiss RE. I-Neuroendocrinology kunye nenkqubo ye-neuroendocrine. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; I-2020: isahluko 210.