5'-nucleotidase

I-5'-nucleotidase (5'-NT) yiprotein eveliswa sisibindi. Uvavanyo lunokwenziwa ukulinganisa isixa sale proteni egazini lakho.

Igazi litsalwa emthanjeni. Unokuziva iintlungu okanye ulwamvila xa kufakwa inaliti. Emva koko, kunokubakho ukuthotywa okuthile.

Umboneleli wakho wezempilo angakuxelela ukuba uyeke ukuthatha amayeza anokuphazamisa uvavanyo. Iziyobisi ezinokuchaphazela iziphumo zibandakanya:

• I-Acetaminophen (iTylenol)
• IHalothane
• Isoniazid
• IMethyldopa
• INitrofurantoin

Umboneleli wakho unokuyalela olu vavanyo ukuba uneempawu zengxaki yesibindi. Isetyenziswa ikakhulu ukuxelela ukuba inqanaba leprotheni ephezulu ngenxa yomonakalo wesibindi okanye ukonakala kwemisipha.

Ixabiso eliqhelekileyo ziiyunithi ezi-2 ukuya kwezi-17 kwilitha nganye.

Qaphela: Uluhlu lwamaxabiso aqhelekileyo luyahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Amanqanaba amakhulu kunesiqhelo anokubonisa:

• Ukuhamba kwe-bile kwisibindi kuyavalwa (cholestasis)
• Ukumelwa yintliziyo
• IHepatitis (isibindi esidlamkileyo)
• Ukungabikho kokuhamba kwegazi esibindini
• Ukufa kweethishu zesibindi
• Umhlaza wesibindi okanye ithumba
• Isifo semiphunga
• Isifo sepancreas
• Ukuqhekeka kwesibindi (i-cirrhosis)
• Ukusetyenziswa kweziyobisi eziyityhefu kwisibindi

Umngcipheko omncinci wokutsalwa kwegazi unokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)
• Ukuthuthuzela

5'-NT

• Uvavanyo lwegazi

ICarty RP, iPincus MR, uSarafranz-Yazdi E.I-enzymology yeklinikhi. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 20.

IPratt DS. I-chemistry yesibindi kunye novavanyo lomsebenzi. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Amathumbu kunye nezifo zesibindi: iPathophysiology / Diagnosis / Management. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 73.