Ukubala kweRBC

Inani le-RBC luvavanyo lwegazi olulinganisa ukuba zingaphi iiseli ezibomvu zegazi (RBCs) onazo.

Ii-RBCs ziqulathe ihemoglobin, ephethe ioksijini. Ubungakanani beoksijini yomzimba wakho efumanekayo ixhomekeke ekubeni zingaphi ii-RBCs onazo kunye nendlela esebenza ngayo.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyimfuneko.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Ubalo lwe-RBC phantse luyinxalenye yovavanyo olupheleleyo lwegazi (CBC).

Uvavanyo lunokunceda ukufumanisa iintlobo ezahlukeneyo ze-anemia (inani eliphantsi lee-RBCs) kunye nezinye iimeko ezichaphazela iiseli ezibomvu zegazi.

Eminye imiqathango enokufuna ukubalwa kweRBC yile:

• Isifo esonakalisa imithambo yegazi yezintso (Alport syndrome)
• Umhlaza weseli emhlophe (Waldenström macroglobulinemia)
• Ukuphazamiseka apho iiseli ezibomvu zegazi zihla kwangoko kunesiqhelo (paroxysmal nocturnal hemoglobinuria)
• Ingxaki yomongo wethambo apho umongo uthatyathelwa indawo ziintsimbi ezibomvu (myelofibrosis)

Uluhlu oluqhelekileyo lweRBC zezi:

• Indoda: I-4.7 ukuya kwi-6.1 yezigidi zeeseli nge-microliter nganye (iiseli / mcL)
• Abasetyhini: 4.2 ukuya kwi-5.4 yezigidi zeeseli / mcL

Uluhlu olungentla apha yimilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Inani elingaphezulu kwenani eliqhelekileyo lee-RBCs linokuba ngenxa yoku:

• Ukutshaya icuba
• Ingxaki ngesakhiwo sentliziyo kunye nomsebenzi okhoyo ekuzalweni (isifo sentliziyo esibelekweni)
• Ukusilela kwicala lasekunene lentliziyo (cor pulmonale)
• Ukuphelelwa ngamanzi emzimbeni (umzekelo, kurhudo)
• Isisu sezintso (renal cell carcinoma)
• Inqanaba leoksijini yegazi ephantsi (hypoxia)
• Ukuqhawula okanye ukuqina kwemiphunga (pulmonary fibrosis)
• Isifo somongo wethambo esibangela ukwanda okungaqhelekanga kwii-RBCs (i-polycythemia vera)

Inani lakho le-RBC liya kunyuka kangangeeveki ezininzi xa usendaweni ephezulu.

Iziyobisi ezinokunyusa inani le-RBC zibandakanya:

• I-Anabolic steroids
• Erythropoietin
• IGentamicin

Amanani angaphantsi kunesiqhelo ee-RBCs anokubangelwa zezi:

• Ukunqongophala kwegazi
• Ukopha
• Ukusilela komongo wethambo (umzekelo, ukusuka kwimitha, ityhefu, okanye ithumba)
• Ukusilela kwehomoni ebizwa ngokuba yi-erythropoietin (ebangelwa sisifo sezintso)
• Ukutshatyalaliswa kwe-RBC (i-hemolysis) ngenxa yotofelo-gazi, ukulimala kwenqanawa yegazi, okanye esinye isizathu
• Ileukemia
• Ukungondleki
• Umhlaza womongo wethambo ubizwa ngokuba yi-myeloma emininzi
• Intsimbi encinci, ubhedu, i-folic acid, ivithamini B6, okanye ivithamini B12 ekudleni
• Amanzi amaninzi emzimbeni (overhydration)
• Ukukhulelwa

Iziyobisi ezinokunciphisa ukubala kwe-RBC zibandakanya:

• Iziyobisi Chemotherapy
• I-chloramphenicol kunye nezinye i-antibiotics
• IiHydantoins
• IMethyldopa
• Izidakamizwa ezichasayo ezichasayo (i-NSAID)
• Iquinidine

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Ukubala kwe-Erythrocyte; Ubalo lweeseli ezibomvu; Anemia - RBC ubalo

• Uvavanyo lwegazi
• Izinto ezenziwe ngegazi
• Uvavanyo lwegazi oluphezulu

IChernecky CC, iBerger BJ. Iseli ebomvu yegazi (RBC) - igazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; Ngo-2013: 961-962.

IGallagher PG. I-hemolytic anemias: inwebu ebomvu yegazi kunye neziphene kwimetabolism. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 152.

Encinci M. Anemia. Ku: Cameron P, Little M, Mitra B, Deasy C, ii-eds. Incwadi yezeMpilo yabantu abadala. Umhla we-5. IPhiladelphia, PA: Elsevier; 2020: isahluko 13.

Kuthetha i-RT. Indlela eya kwii-anemias. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 149.