Testosterone

Uvavanyo lwe testosterone lilinganisela inani lehomoni eyindoda, testosterone, egazini. Bobabini abesilisa nabasetyhini bavelisa le hormone.

Uvavanyo oluchazwe kweli nqaku lilinganisa inani elipheleleyo le testosterone egazini. Uninzi lwe testosterone egazini lubotshelelwe kwiproteni ebizwa ngokuba yihomoni yesondo ebopha i-globulin (SHBG). Olunye uvavanyo lwegazi lunokulinganisa i "testosterone" yasimahla. Nangona kunjalo, olu hlobo lovavanyo aluhlali luchanekile.

Isampuli yegazi ithathwa emthanjeni. Elona xesha lilungileyo lokuba kuthathwe isampulu yegazi liphakathi kwe-7 kusasa kunye ne-10 kusasa Isampulu yesibini ihlala ifuneka ukuqinisekisa umphumo ongaphantsi kunokuba bekulindelwe.

Umboneleli wezempilo angakucebisa ukuba uyeke ukuthatha amayeza anokuchaphazela uvavanyo.

Unokuziva uhlaba kancinci okanye uluma xa kufakwa inaliti. Kunokubakho ukuphazamiseka emva koko.

Olu vavanyo lunokwenziwa ukuba uneempawu zokuveliswa kwendoda engalunganga (androgen).

Kwindoda, amasende avelisa uninzi lwe testosterone emzimbeni. Amanqanaba ahlala ehlolwa ukuvavanya imiqondiso ye testosterone engaqhelekanga enje:

• Ukufikisa kwasekuqaleni okanye kade (ebafaneni)
• Ukungachumi, ukungasebenzi kakuhle kwe-erectile, inqanaba eliphantsi lomdla wesini, ukuncipha kwamathambo (emadodeni)

Kwabasetyhini, ii-ovari zivelisa uninzi lwe testosterone. Amadlala adrenal anokuvelisa okuninzi kakhulu kwezinye ii-androgens eziguqulwe zaba yi testosterone. Amanqanaba ahlala ehlolwa ukuvavanya iimpawu zamanqanaba aphezulu e-testosterone, anje ngala:

• Amabala, ulusu olunamafutha
• Guqula ngelizwi
• Ukunciphisa ubungakanani besifuba
• Ukukhula kweenwele okugqithileyo (mnyama, ziinwele ezixineneyo kwindawo yamadevu, iindevu, ukuqaqamba, isifuba, iimpundu, amathanga angaphakathi)
• Ukonyusa ubungakanani be-clitoris
• Ukuhamba rhoqo okanye ukungabikho exesheni
• Impandla yamadoda okanye ukuchetywa kweenwele

Imilinganiselo eqhelekileyo yale mvavanyo:

• Indoda: I-300 ukuya kwi-1 000 i-nanograms nge-deciliter nganye (ng / dL) okanye i-10 ukuya kwi-35 i-nanomoles ilitha nganye (nmol / L)
• Ibhinqa: 15 ukuya ku-70 ng / dL okanye i-0.5 ukuya kwi-2.4 nmol / L

Le mizekelo ingentla yimilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Iimeko ezithile zempilo, amayeza, okanye ukwenzakala kunokukhokelela kwi-testosterone esezantsi. Inqanaba leTesttosterone nalo lihla ngokwendalo. I-testosterone esezantsi inokuchaphazela ukuqhuba ngokwesondo, imood, kunye nobunzima bamasipha emadodeni.

Ukwehla kwe testosterone iyonke kunokuba ngenxa:

• Isigulo esinganyangekiyo
• Idlala lengqula alivelisi izixa ezithile okanye zonke iihomoni zalo
• Ingxaki ngemimandla yengqondo elawula iihomoni (hypothalamus)
• Umsebenzi we-thyroid ophantsi
• Ukulibaziseka kokufikisa
• Izifo zamasende (umothuko, umhlaza, usulelo, amajoni omzimba, ukugcwala kwentsimbi)
• Ithumba leBenign yeeseli zepituitary ezivelisa kakhulu i-hormone prolactin
• Amanqatha amaninzi omzimba (ukukhuluphala)
• Iingxaki zokulala (ukuphazamiseka kokuphefumla kokulala)
  
• Uxinzelelo olungapheliyo lokuzilolonga kakhulu (ukujonga isifo)
  

Ukunyuka kwenqanaba le testosterone kunokubangelwa:

• Ukuchasana nokusebenza kwehomoni yamadoda (ukumelana ne-androgen)
• Ukudumba kwamaqanda
• Umhlaza wamatyhalarha
• I-hyperplasia yokuzalwa ye-adrenal
• Ukuthatha amayeza okanye iziyobisi ezonyusa inqanaba le testosterone (kubandakanya ezinye izongezo)

I-serum testosterone

Rey RA, Josso N.Ukuchongwa kunye nokunyangwa kokuphazamiseka kuphuhliso lwezesondo. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 119.

IRosenfield RL, iBarnes RB, i-Ehrmann DA. Hyperandrogenism, hirsutism, kunye ne-polycystic ovary syndrome. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 133.

I-Swerdloff RS, i-Wang C. I-testis kunye ne-hypogonadism yamadoda, ukungachumi, kunye nokungasebenzi kakuhle ngokwesondo. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 221.