I-Leflunomide

Umxholo

• Ngaphambi kokuba uthathe i-leflunomide,
• I-Leflunomide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye AMANYATHELO AKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Musa ukuthatha i-leflunomide ukuba ukhulelwe okanye ucwangcise ukukhulelwa. I-Leflunomide inokulimaza umbungu. Akufanele uqale ukuthatha i-leflunomide de uthathe uvavanyo lokukhulelwa oluneziphumo ezibi kwaye ugqirha wakho ukuxelela ukuba awukhulelwe. Kuya kufuneka usebenzise indlela esebenzayo yolawulo lokuzalwa ngaphambi kokuba uqale ukuthatha i-leflunomide, ngexesha lonyango lwakho lwe-leflunomide, kunye neminyaka emi-2 emva konyango. Ukuba ixesha lakho lihambile okanye uphulukene nexesha lokunyanga kunye ne-leflunomide, tsalela umnxeba kwangoko. Thetha nogqirha wakho ukuba ucwangcisa ukukhulelwa kwisithuba seminyaka emi-2 emva kokuyeka unyango nge-leflunomide. Ugqirha wakho unokumisela unyango oluya kunceda ukususa la mayeza ngokukhawuleza emzimbeni wakho.

I-Leflunomide inokubangela umonakalo wesibindi onokusongela ubomi kwaye ubangele nokufa. Umngcipheko wokonakaliswa kwesibindi ngowona mkhulu kubantu abathatha amanye amayeza awaziwayo ukuba abangele ukonakala kwesibindi, nakubantu esele benesifo sesibindi. Xelela ugqirha wakho ukuba ukhe waba ne-hepatitis okanye naluphi na olunye uhlobo lwesifo sesibindi kwaye ukuba uyasela okanye ukhe wasela izixa ezikhulu zotywala. Xelela ugqirha wakho kunye nosokhemesti ukuba uthatha i-acetaminophen (iTylenol, kwezinye iimveliso ezithengiswa ekhawuntareni), i-aspirin kunye nezinye iyeza ezichasayo (ii-NSAID ezinje nge-ibuprofen [Advil, Motrin] kunye ne naproxen [Aleve, Naprosyn], cholesterol -ukunyanga amayeza (iitemins), ihydroxychloroquine, iimveliso zentsimbi, isoniazid (Laniazid, eRifamate, eRifater), methotrexate (Trexall), niacin (nicotinic acid), okanye rifampin (Rifadin, Rimactane, eRifamate, eRifater). amava naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: isicaphucaphu, ukudinwa kakhulu, ukopha okungaqhelekanga okanye ukugruzuka, ukungabi namandla, ukuphelelwa ngumdla, iintlungu kwinxalenye ephezulu yesisu, ukuba tyheli kolusu okanye amehlo, umbala omnyama umchamo, okanye iimpawu ezifana nomkhuhlane.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-leflunomide.

Thetha nogqirha wakho malunga nomngcipheko wokuthatha i-leflunomide.

I-Leflunomide isetyenziswa yodwa okanye idityaniswe namanye amayeza ukunyanga isifo samathambo (imeko apho umzimba uhlasela amalungu ayo, ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi). I-Leflunomide ikwiklasi yamayeza abizwa ngokuba sisifo esiguqula amachiza okulwa isifo (i-DMARD). Isebenza ngokunciphisa ukuvuvukala kunye nokunciphisa inkqubela phambili yemeko, enokukunceda ukuphucula ukusebenza komzimba wabantu abane-rheumatoid arthritis.

I-Leflunomide iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kanye ngemini. Ugqirha wakho unokukuxelela ukuba uthathe idosi enkulu ye-leflunomide kwiintsuku zokuqala ezi-3 zonyango. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-leflunomide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho unokufuna ukunciphisa idosi okanye ayeke unyango ukuba uneziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ngexesha lonyango lwakho.

I-Leflunomide inokunceda ukulawula iimpawu zesifo samathambo kodwa ayiyinyangi. Qhubeka nokuthatha i-leflunomide nokuba uziva uphilile. Sukuyeka ukuthatha i-leflunomide ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-leflunomide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-leflunomide, teriflunomide (Aubagio), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-leflunomide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayo nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin Jantoven); cholestyramine (Prevalite); iikhompawundi zegolide ezinje nge-auranofin (Ridaura); amayeza ukunyanga umhlaza; amanye amayeza acinezela amajoni omzimba njenge-azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), kunye ne-tacrolimus (Astagraf, Prograf); penicillamine (Cuprimine, Depen), kunye ne-tolbutamide. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wosuleleka kanobom okanye ukhe wosuleleka kaninzi, umhlaza okanye ezinye iimeko ezichaphazela umongo wethambo okanye amajoni omzimba (kubandakanya intsholongwane kaGawulayo) [i-HIV] kunye ne-immunodeficiency syndrome [AIDS]), isifo seswekile, okanye isifo sezintso.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa uthatha i-leflunomide.
• ukuba ucwangcisa ukuba ngutata womntwana, kuya kufuneka uthethe nogqirha wakho malunga nokuyeka i-leflunomide kunye nokufumana unyango lokunceda ukususa la mayeza emzimbeni wakho ngokukhawuleza.
• Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-leflunomide.
• Ukuthatha i-leflunomide kunokunciphisa ukubanakho kwakho ukulwa usulelo. Tshela ugqirha wakho ukuba unosulelo ngoku okanye ukuba unayo nayiphi na imiqondiso yosulelo enjengomkhuhlane, ukukhohlela, okanye iimpawu ezinje ngomkhuhlane. Ukuba ufumana naziphi na kwezi mpawu zilandelayo ngexesha lonyango lwakho kunye ne-leflunomide, tsalela ugqirha wakho: umkhuhlane; umqala obuhkungu; ukukhohlela; iimpawu ezifana nomkhuhlane; indawo enesikhumba esifudumeleyo, esibomvu, esidumbileyo, okanye esibuhlungu; ukuchama kabuhlungu, kunzima, okanye rhoqo; okanye ezinye iimpawu zosulelo. Unyango lwakho lwe-leflunomide lunokufuna ukuphazanyiswa ukuba unentsholongwane.
• Usenokuba sele wosulelwe sisifo sephepha (i-TB; isifo esibuhlungu semiphunga) kodwa ungabi nazimpawu zesi sifo. Kule meko, i-leflunomide inokwenza usulelo lwakho lube lubi kakhulu kwaye lubangele ukuba ube neempawu. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanaso na isifo sephepha, ukuba wakhe wakha okanye watyelela ilizwe apho ixhaphake khona i-TB, okanye ukuba ukhe wakufutshane nomntu owakhe okanye owakhe wanaso. Phambi kokuba uqale unyango lwakho nge-leflunomide, ugqirha wakho uya kwenza uvavanyo lolusu ukubona ukuba unayo i-TB. Ukuba unayo i-TB, ugqirha wakho uya kulunyanga olu sulelo ngee-antibiotics ngaphambi kokuba uqale ukuthatha i-leflunomide.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho.
• Kuya kufuneka uyazi ukuba i-leflunomide inokubangela uxinzelelo lwegazi oluphezulu. Kuya kufuneka ujongiwe uxinzelelo lwegazi ngaphambi kokuqala unyango kwaye rhoqo ngelixa usela la mayeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Leflunomide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukugabha
• isilungulela
• intloko ebuhlungu
• isiyezi
• ukuhla ukusinda
• umqolo obuhlungu
• iintlungu zemisipha okanye ubuthathaka
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni
• ukulahleka kweenwele
• iinyanda zomlenze
• isikhumba esomileyo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo okanye ezo zidweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye AMANYATHELO AKHETHEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukukhawuleza kunye okanye ngaphandle komkhuhlane
• urhwebo
• i-blisters okanye ukuxobuka kwesikhumba
• izilonda zomlomo
• ukurhawuzelela
• ubunzima bokuphefumla
• ukukhwehlela okutsha okanye okuya kusiba mandundu
• iintlungu zesifuba
• ulusu oluthuthu

Ukufumana amayeza acinezela amajoni omzimba kunokunyusa umngcipheko wokuphuhlisa iintlobo ezithile zomhlaza. Ukonyuka komhlaza akuxelwanga kwizifundo zeklinikhi kunye ne-leflunomide ukuza kuthi ga ngoku. Thetha nogqirha wakho malunga nomngcipheko wokufumana i-leflunomide.

I-Leflunomide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela) kunye nokukhanya.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• urhudo
• isisu esibuhlungu
• ukudinwa kakhulu
• ubuthathaka
• ulusu oluthuthu
• ukubetha kwentliziyo ngokukhawuleza
• ukuqhawukelwa ngumphefumlo

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Arava^®