Umbhali: Joan Hall
Umhla Wokudalwa: 3 Eyomdumba 2021
Hlaziya Umhla: 19 Eyenkanga 2024
Anonim
SURPASS ET: ropeginterferon versus anagrelide as second line therapy in essential thrombocythemia
Ividiyo: SURPASS ET: ropeginterferon versus anagrelide as second line therapy in essential thrombocythemia

Umxholo

I-Anagrelide isetyenziselwa ukunciphisa inani leeplatelets (uhlobo lweseli yegazi elifunekayo ukulawula ukopha) egazini lezigulana ezinengxaki yomongo wethambo, apho umzimba wenza uninzi lweentlobo zeeseli zegazi, njenge-thrombocythemia ebalulekileyo (imeko apho umzimba wenza iiplatelets ezininzi) okanye i-polycythemia vera (imeko apho umzimba wenza iiseli ezibomvu zegazi kwaye ngamanye amaxesha iiplatelets ezininzi). I-Anagrelide ikwiklasi yamayeza ebizwa ngokuba ziiarhente zokunciphisa iplatelet. Isebenza ngokunciphisa imveliso yeeplatelets emzimbeni.

I-Anagrelide iza njengepilisi yokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya amaxesha amabini okanye amane ngemini. Thatha i-anagrelide ngamaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-anagrelide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.


Ugqirha wakho uya kukuqala ngedosi esezantsi ye-anagrelide kwaye ngokuthe ngcembe ayonyuse idosi yakho, hayi rhoqo rhoqo kube kanye ngeveki. Ugqirha wakho unokutshintsha idosi yakho ngexesha lonyango lwakho esekwe kwimpendulo yomzimba wakho kunyango. Landela le miyalelo ngononophelo.

I-Anagrelide inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Qhubeka nokuthatha i-anagrelide nokuba uziva uphilile. Sukuyeka ukuthatha i-anagrelide ngaphandle kokuthetha nogqirha wakho. Ukuba ngequbuliso uyeka ukuthatha i-anagrelide, inani leeplatelets egazini lakho liya kunyuka kwaye unokufumana iimpawu.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuthatha i-anagrelide,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-anagrelide okanye naliphi na iyeza.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: atazanavir (Reyataz); Iililostazol (Pletal); cimetidine (iTagamet); i-clozapine (iClozaril); cyclobenzaprine (Flexeril); i-fluoroquinolone antibiotics kubandakanya i-ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), abanye; i-fluvoxamine (iLuvox); imipramine (Tofranil); inamrinone; mexiletine (Mexitil); iMilrinone (iPrimacor); naproxen (Aleve, Naprosyn, kwi-Prevacid NapraPAC); iriluzole (Rilutek); I-sucralfate (iKarafate); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Theolair, nabanye); kunye ne-ticlopidine (Ticlid). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe wanengxaki yokopha; uxinzelelo lwegazi oluphezulu okanye oluphantsi; Ukunganyamezelani kwe-lactose (ukungakwazi ukwetyisa iimveliso zobisi) okanye intliziyo, izintso, okanye isifo sesibindi.
  • ungathathi i-anagrelide ukuba ukhulelwe okanye ucwangcise ukukhulelwa Kuya kufuneka usebenzise indlela esebenzayo yolawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho ne-anagrelide. Thetha nogqirha wakho malunga neentlobo zolawulo lokuzalwa ezifanelekileyo kuwe. Ukuba uyakhulelwa ngelixa uthatha i-anagrelide, tsalela umnxeba kwangoko. Musa ukuncancisa xa uthatha i-anagrelide.
  • ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-anagrelide.
  • Kuya kufuneka uyazi ukuba i-anagrelide inokukwenza ube nesiyezi, ngakumbi xa uqala ukuthatha amayeza. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
  • Kuya kufuneka uyazi ukuba i-anagrelide inokubangela ukuba ube nesiyezi, ukuba nentloko elula, kunye nokuphelelwa ngamandla xa usukuma ngokukhawuleza kwindawo olele kuyo. Oku kuqheleke ngakumbi xa uqala ukuthatha i-anagrelide. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.
  • cwangcisa ukuthintela ukukhanya elangeni ngokungeyomfuneko okanye ixesha elide kunye nokunxiba impahla ekhuselayo, iiglasi zelanga kunye nescreen selanga. I-Anagrelide inokwenza ulusu lwakho lubuthathaka kwilanga.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa uthatha eli yeza.


Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Anagrelide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • intloko ebuhlungu
  • irhasi
  • isicaphucaphu
  • ukugabha
  • urhudo
  • ukuqhina
  • isisu esibuhlungu
  • isilungulela
  • ukubhinqa
  • Ukuphelelwa ngumdla wokutya
  • impumlo enemifinya
  • impumlo
  • umqala obuhkungu
  • izilonda zomlomo
  • isiyezi
  • ukudakumba
  • uvalo
  • ukulibala
  • ukudideka
  • ubunzima bokulala okanye ukulala
  • ukungabikho kwamandla okanye ukulala
  • ubuthathaka
  • iintlungu zemisipha, zelungu okanye zomqolo
  • iinyanda zomlenze
  • ukulahleka kweenwele
  • ifiva
  • Iimpawu ezinjengomkhuhlane
  • ukuchama kabuhlungu
  • kukhala ezindlebeni
  • ukurhawuzelela

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

  • irhashalala
  • urhwebo
  • ukopha okungaqhelekanga okanye ukugruzuka
  • igazi kumchamo okanye isitulo
  • ezimnyama okanye ezilindileyo
  • iintlungu zesifuba
  • Ukuziva ubethabethana esifubeni
  • ukukhawuleza, ukunyanzelisa, okanye ukubetha kwentliziyo okungaqhelekanga
  • ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
  • ubunzima bokuphefumla
  • ukukhohlela
  • intetho ecothayo okanye enzima
  • isiqaqa
  • ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze
  • intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
  • ukuxhuzula
  • utshintsho kumbono

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).


Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nokukhanya okanye ubushushu obugqithisileyo kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

  • ukopha okungaqhelekanga okanye ukugruzuka

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-anagrelide.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Igama loqhagamshelwano Agrylin®
Ukuhlaziywa kokugqibela-08/15/2015

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