Inaliti yeMitoxantrone

Umxholo

• Ngaphambi kokusebenzisa inaliti ye-mitoxantrone,
• Inaliti yeMitoxantrone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

IMitoxantrone kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekusetyenzisweni kwamayeza e-chemotherapy.

IMitoxantrone inokubangela ukwehla kwenani leeseli ezimhlophe egazini. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu rhoqo ngaphambi kwaye ngexesha lonyango lwakho ukujonga ukuba inani leeseli ezimhlophe zegazi emzimbeni wakho lehlile. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umkhuhlane, ukugodola, umqala obuhlungu, ukukhohlela, ukuchama rhoqo okanye ukubabuhlungu, okanye ezinye iimpawu zosulelo.

Inaliti yeMitoxantrone inokubangela umonakalo entliziyweni yakho ngalo naliphi na ixesha kunyango lwakho okanye kwiinyanga ukuya kwiminyaka emva kokuba unyango lwakho luphelile. Lo monakalo wentliziyo unokuba mbi kwaye unokubangela ukufa kwaye unokwenzeka nakubantu ngaphandle komngcipheko wesifo sentliziyo. Ugqirha wakho uyakukuvavanya kwaye enze uvavanyo oluthile ukukhangela ukuba isebenza njani intliziyo yakho ngaphambi kokuqala unyango nge-mitoxantrone kwaye ukuba ubonakalisa naziphi na iimpawu zeengxaki zentliziyo. Ukuba usebenzisa i-mitoxantrone injection ye-multiple sclerosis (MS; imeko apho iimbilini zingasebenzi kakuhle, kubangele iimpawu ezinjengobuthathaka; ukuphazamiseka; ukulahleka kokulungelelaniswa kwemisipha; kunye neengxaki ngombono, intetho kunye nokulawula isinyi), ugqirha wakho Uya kwenza uvavanyo oluthile phambi kwedosi nganye yenaliti ye-mitoxantrone kunye nonyaka emva kokuba ulugqibile unyango lwakho. Olu vavanyo lunokubandakanya i-electrocardiogram (ECG; uvavanyo olurekhoda umsebenzi wombane wentliziyo) kunye ne-echocardiogram (uvavanyo olusebenzisa amaza esandi ukulinganisa ukubanakho kwentliziyo yokupompa igazi). Ugqirha wakho angakuxelela ukuba akufuneki ufumane eli yeza xa uvavanyo lubonisa ukubanakho kwentliziyo yakho yokupompa igazi. Xelela ugqirha wakho ukuba ukhe wanalo naluphi na uhlobo lwesifo sentliziyo okanye unyango ngemitha (x-ray) kwindawo yesifuba. Tshela ugqirha wakho kunye nosokhemesti ukuba uthatha okanye wakhe wafumana amayeza athile e-chemotherapy anje nge-daunorubicin (Cerubidine), doxorubicin (Doxil), epirubicin (Ellence), okanye idarubicin (Idamycin), okanye ukuba ukhe wanyangwa nge-mitoxantrone in ixesha eladlula. Umngcipheko womonakalo wentliziyo unokuxhomekeka kwinani elipheleleyo le-mitoxantrone enikwe umntu ngaphezulu kobomi bakho bonke, ke ugqirha wakho uya kuthi anciphise inani leedosi ozifumanayo ukuba usebenzisa eli yeza kwi-MS. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngokukhawuleza: ubunzima bokuphefumla, iintlungu zesifuba, ukudumba kwemilenze okanye amaqatha, okanye ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo.

I-Mitoxantrone inokunyusa umngcipheko wokuphuhlisa i-leukemia (umhlaza weeseli ezimhlophe zegazi), ngakumbi xa inikwa ngeedosi eziphezulu okanye kunye namanye amayeza e-chemotherapy.

Thetha nogqirha wakho malunga nomngcipheko wokusebenzisa inaliti mitoxantrone.

Inaliti yeMitoxantrone isetyenziselwa abantu abadala abaneendlela ezahlukeneyo ze-multiple sclerosis (MS; isifo esingasebenzi kakuhle kwimithambo-luvo kwaye abantu banokufumana ubuthathaka, ukuba ndindisholo, ukuphulukana nokulungelelaniswa kwezihlunu, kunye neengxaki zombono, intetho, kunye nolawulo lwesinyi) kubandakanya ezilandelayo:

• Iifom zokuphinda zibuyele kwakhona (ikhosi yesifo apho iimpawu ziyavela khona amaxesha ngamaxesha), okanye
• ukubuyela umva ngokuqhubekayo (ikhosi yesi sifo ngamanye amaxesha), okanye
• iifomati zesekondari eziqhubekayo (ikhosi yesifo apho ukubuyela umva kwenzeka rhoqo).

Inaliti yeMitoxantrone ikwasetyenziswa kunye namayeza e-steroid ukunciphisa iintlungu kubantu abanomhlaza wesifo se-Prostate abangaphendulanga kwamanye amayeza. Inaliti yeMitoxantrone ikwasetyenziswa namanye amayeza ukunyanga iintlobo ezithile zegazi. Inaliti yeMitoxantrone ikudidi lwamayeza abizwa ngokuba zii-anthracenediones. IMitoxantrone inyanga i-MS ngokumisa iiseli ezithile zamajoni omzimba ekufikeleleni kwingqondo nakwintambo yomqolo kunye nokwenza umonakalo. IMitoxantrone inyanga umhlaza ngokunqanda ukukhula kunye nokusasazeka kweeseli zomhlaza.

Inaliti yeMitoxantrone iza njengamanzi ukuba anikwe ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi esibhedlele okanye ekliniki. Xa kusetyenziswa inaliti ye-mitoxantrone ukunyanga i-MS, ihlala inikwa kanye kwiinyanga ezi-3 malunga neminyaka emi-2 ukuya kwemi-3 (iyonke iidosi eziyi-8 ukuya kwezili-12). Xa inaliti ye-mitoxantrone isetyenziselwa ukunyanga umhlaza wedlala lesinyi, ihlala inikwa kube kanye kwiintsuku ezingama-21. Xa kusetyenziswa inaliti ye-mitoxantrone ukunyanga i-leukemia, uya kuqhubeka nokufumana la mayeza ngokusekwe kwimeko yakho kunye nendlela osabela ngayo kunyango.

Ukuba usebenzisa inaliti ye-mitoxantrone ye-MS, kuya kufuneka uyazi ukuba ilawula i-MS kodwa ayiyinyangi. Qhubeka ufumana unyango nokuba uziva uphilile. Thetha nogqirha wakho ukuba awusafuni kufumana unyango ngenaliti ye-mitoxantrone.

Ukuba usebenzisa inaliti ye-mitoxantrone ye-MS, buza usokhemesti okanye ugqirha wakho ikopi yolwazi lomenzi wesigulana.

Inaliti yeMitoxantrone ngamanye amaxesha isetyenziselwa ukunyanga i-non-Hodgkin's lymphoma (NHL; umhlaza oqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti ye-mitoxantrone,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana nenaliti ye-mitoxantrone, nawaphi na amanye amayeza, ii-sulfites, okanye ezinye izithako ezenzelwe inaliti ye-mitoxantrone. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanayo nayiphi na ingxaki yokunqanda igazi, i-anemia (ukunciphisa inani leeseli ezibomvu egazini), okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Akufanele ukhulelwe ngelixa usebenzisa inaliti ye-mitoxantrone. Thetha nogqirha wakho malunga neendlela ezifanelekileyo zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwe ngelixa usebenzisa inaliti ye-mitoxantrone, tsalela umnxeba kwangoko. Inaliti yeMitoxantrone inokwenzakalisa umntwana ongekazalwa. Ukuba usebenzisa i-mitoxantrone injection ukunyanga i-MS, nokuba usebenzisa ulawulo lokuzalwa, ugqirha wakho kufuneka akunike uvavanyo lokukhulelwa ngaphambi konyango ngalunye. Kuya kufuneka uvavanyo lokukhulelwa olungelulo ngaphambi kokuqala kwonyango ngalunye.
• xelela ugqirha wakho ukuba uncelisa. Musa ukuncancisa ngelixa usebenzisa inaliti yemitoxantrone.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa inaliti ye-mitoxantrone.
• Kuya kufuneka uyazi ukuba inaliti ye-mitoxantrone imnyama ngombala kwaye inokubangela ukuba iinxalenye ezimhlophe zamehlo akho zibe nombala oluhlaza okwesibhakabhaka kangangeentsuku ezimbalwa emva kokuba ufumene idosi nganye. Ingatshintsha kwakhona umbala womchamo wakho kumbala oluhlaza okwesibhakabhaka malunga neeyure ezingama-24 emva kokufumana idosi.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Shayela ugqirha wakho ngokukhawuleza ukuba awukwazi ukugcina ixesha lokufumana i-dose ye-mitoxantrone injection.

Inaliti yeMitoxantrone inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• isilungulela
• Ukuphelelwa ngumdla wokutya
• izilonda emlonyeni naselulwimini
• impumlo egobileyo okanye egxunyekwe
• ukucheba okanye ukulahleka kweenwele
• utshintsho kwindawo ejikeleze okanye ngaphantsi kweenzipho kunye neenzwane
• ukuphoswa okanye ukungahambi kakuhle kokuya exesheni
• ukudinwa kakhulu
• ubuthathaka
• intloko ebuhlungu
• umqolo obuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• ukopha okungaqhelekanga okanye ukugruzuka
• amachaphaza amancinci abomvu okanye mfusa kulusu
• urhwebo
• ukurhawuzelela
• irhashalala
• kunzima ukugwinya
• ukuqhawukelwa ngumphefumlo
• isiqaqa
• isiyezi
• ulusu oluthuthu
• mthubi ulusu okanye amehlo
• ukuxhuzula
• ububomvu, iintlungu, ukudumba, ukutshisa, okanye umbala omnyama okwesibhakabhaka kwindawo enikezwe inaliti

Inaliti yeMitoxantrone inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwisitofu semitoxantrone.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-mitoxantrone.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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