Inaliti ye-Isavuconazonium

Umxholo

• Ngaphambi kokufumana inaliti ye-isavuconazonium,
• Inaliti ye-Isavuconazonium inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

Inaliti ye-Isavuconazonium isetyenziselwa ukunyanga izifo ezosulelayo ezinje nge-aspergillosis (usulelo lokungunda oluqala emiphungeni kwaye lusasazeka ngokuhamba kwegazi kwamanye amalungu) kunye ne-mucormycosis (intsholongwane yokungunda edla ngokuqala kwizono, kwingqondo okanye kwimiphunga) . Inaliti ye-Isavuconazonium ikudidi lwamayeza abizwa ngokuba yi-azole antifungals. Isebenza ngokunciphisa ukukhula komngundo obangela usulelo.

Inaliti ye-Isavuconazonium iza njengomgubo oxutywe nolwelo kwaye itofelwe ngaphakathi ngaphakathi (emthanjeni). Ihlala inikwa ngaphezulu kweyure eli-1 rhoqo kwiiyure ezisi-8 kwiidosi zokuqala ezintandathu kwaye kube kanye ngemini. Ubude bonyango lwakho buxhomekeke kwimpilo yakho ngokubanzi, uhlobo losulelo onalo, kunye nendlela ophendula ngayo kunyango. Unokufumana inaliti ye-isavuconazonium esibhedlele okanye unokuhambisa amayeza ekhaya. Ukuba uza kufumana inaliti ye-isavuconazonium ekhaya, umboneleli wakho wezempilo uya kukubonisa indlela yokusebenzisa amayeza. Qiniseka ukuba uyayiqonda le ndlela, kwaye ubuze umboneleli wakho ukuba unemibuzo.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-isavuconazonium,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-isavuconazonium, i-fluconazole, i-itraconazole, i-ketoconazole, i-posaconazole, i-voriconazole, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ye-isavuconazonium. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha icarbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, e Kaletra), okanye iSt. Ugqirha wakho uya kukuxelela ukuba ungasebenzisi inaliti ye-isavuconazonium ukuba uthatha elinye okanye ngaphezulu kwala mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ), sirolimus (Rapamune), okanye itacrolimus (Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-isavuconazonium, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho ukhe waba ne-QT syndrome emfutshane (imeko eyonyusa umngcipheko wokubetha kwentliziyo ngendlela engaqhelekanga, isiyezi, ukuphelelwa ngamandla okanye ukufa ngesiquphe). Ugqirha wakho uya kukuxelela ukuba ungayifumani inaliti ye-isavuconazonium.
• xelela ugqirha wakho ukuba ukhe wanengxaki yentliziyo okanye yesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa ufumana inaliti ye-isavuconazonium, biza ugqirha wakho.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yamagilebhisi ngelixa ufumana lamayeza.

Inaliti ye-Isavuconazonium inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukuqhina
• intloko ebuhlungu
• umqolo obuhlungu
• ukukhohlela
• ubunzima bokulala okanye ukulala
• ixhala
• ukuphazamiseka
• ukudideka
• ukunciphisa ukutya

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhwebo
• irhashalala
• ukurhawuzelela
• Ukuxobuka okanye ukudumba kolusu
• isicaphucaphu
• ukugabha
• mthubi ulusu okanye amehlo
• ukudinwa kakhulu
• Iimpawu ezinjengomkhuhlane
• iintlungu zemisipha, iicramps, okanye ubuthathaka
• ukubetha kwentliziyo ngokungaqhelekanga
• ukudumba kwezandla, iinyawo, iingalo okanye imilenze
• ubunzima bokuphefumla okanye ukugwinya
• isiqaqa
• ukungaboni kakuhle
• isiyezi
• Ukugodola
• ukuba ndindisholo, ukutshisa, okanye ukurhawuzelela izandla, iingalo, iinyawo okanye imilenze
• utshintsho kwindlela yakho yokubamba

Inaliti ye-Isavuconazonium inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• intloko ebuhlungu
• isiyezi
• intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
• ukozela
• kunzima ukugxila
• utshintsho ngengqondo yokungcamla
• umlomo owomileyo
• ukuba ndindisholo emlonyeni
• urhudo
• ukugabha
• ukubomvu ngokukhawuleza ngequbuliso kobuso, intamo, okanye isifuba esingaphezulu
• ixhala
• ukungazinzi
• ukubetha okanye ukubetha kwentliziyo okukhawulezayo
• ubuntununtunu bamehlo ekukhanyeni
• intlungu edibeneyo

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwisitofu se-isavuconazonium.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UCremba^® I.V.