Inaliti ye-Moxetumomab Pasudotox-tdfk

Umxholo

• Ngaphambi kokufumana inaliti ye-moxetumomab pasudotox-tdfk,
• Inaliti ye-Moxetumomab pasudotox-tdfk inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO okanye INDLELA yamacandelo, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Moxetumomab pasudotox-tdfk inokubangela ukusabela okunamandla okanye okusongela ubomi okubizwa ngokuba yi-capillary leak syndrome (imeko ebangela ulwelo olugqithisileyo emzimbeni, uxinzelelo lwegazi olusezantsi, kunye namanqanaba asezantsi eproteni [albumin] egazini). Ukuba unazo naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: ukudumba kobuso, izandla, iinyawo, amaqatha, okanye imilenze esezantsi; ukutyeba kwakho; ukuqhawukelwa ngumphefumlo; ukukhohlela; isiqaqa; utywala okanye intloko; okanye ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga.

Inaliti ye-Moxetumomab pasudotox-tdfk inokubangela i-hemolytic uremic syndrome (imeko enokububeka esichengeni ubomi ebandakanya ukwenzakala kwiiseli ezibomvu zegazi, kubangele iingxaki zeanemia kunye nezintso). Xelela ugqirha wakho ukuba ukhe unesifo sezintso. Ukuba unazo naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: izitulo ezibomvu okanye ezinegazi okanye urhudo; ukuncipha kokuchama; igazi kumchamo; utshintsho kwiimvakalelo okanye ekuziphatheni; ukuxhuzula; ukudideka; ukuqhawukelwa ngumphefumlo; ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi; ukopha okungaqhelekanga okanye ukugruzuka; isisu esibuhlungu; ukugabha; ifiva; ulusu oluthuthu; ukudinwa okungaqhelekanga okanye ubuthathaka.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile ngaphambi, ngexesha, nasemva konyango lwakho ukujonga impendulo yomzimba wakho kwi-moxetumomab pasudotox-tdfk inaliti.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-moxetumomab pasudotox-tdfk inaliti kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Inaliti ye-Moxetumomab pasudotox-tdfk isetyenziselwa ukunyanga i-leukemia yeseli enoboya (umhlaza wohlobo oluthile lweeseli ezimhlophe zegazi) obuyileyo okanye ongaphendulanga emva kwezinye iindlela zonyango ezimbini zomhlaza. Inaliti ye-Moxetumomab pasudotox-tdfk ikudidi lwamayeza abizwa ngokuba zii-antibodies ze-monoclonal. Isebenza ngokunceda amajoni akho omzimba ukuba acothise okanye ayeke ukukhula kweeseli zomhlaza.

Inaliti ye-Moxetumomab pasudotox-tdfk iza njengomgubo oxutywe nolwelo kwaye itofwe emthanjeni ngugqirha okanye ngumongikazi kwiofisi yezonyango okanye esibhedlele. Ihlala itofwe kancinci kwisithuba semizuzu engama-30 ngeentsuku zoku-1, 3, no-5 zomjikelo wonyango weentsuku ezingama-28. Lo mjikelo unokuphindaphindwa ukuya kuthi ga kwimijikelo emi-6. Ubude bonyango buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo.

Ngexesha lonyango lwakho, ugqirha wakho uya kukucela ukuba usele iiglasi ezilishumi elinambini ze-8-oz ezinjengamanzi, ubisi okanye ijusi qho kwiiyure ezingama-24 ngeentsuku zoku-1 ukuya kwezi-8 kumjikelo ngamnye wonyango weentsuku ezingama-28.

I-Moxetumomab inokubangela iimpendulo ezinzulu ngexesha okanye emva kokufumana ukunyuswa kwakho. Uya kunikwa amayeza kwimizuzu engama-30 ukuya kwengama-90 ngaphambi kokufakwa kwakho nasemva kokufakwa kwakho ukunceda ukuthintela iimpendulo kwi-moxetumomab. Ugqirha wakho unokufuna ukuyeka unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Tshela ugqirha wakho ukuba unazo naziphi na kwezi mpawu zilandelayo: ukuba nesiyezi, ukuphelelwa ngamandla, ukuphefumla ngamandla okanye ukuphefumla nzima, ukuphefumla kancinci, ukubetha kwentliziyo okukhawulezayo, iintlungu zemisipha, isicaphucaphu, ukugabha, intloko ebuhlungu, umkhuhlane, ukugodola, ukukhohlela, ukutyhafa, ubushushu, okanye ukugungxula . Kubalulekile ukuba uxelele ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-moxetumomab pasudotox-tdfk. Biza ugqirha wakho ngoko nangoko okanye ufumane unyango olukhawulezileyo ukuba ufumana naziphi na kwezi mpawu emva kokuba ushiye iofisi kagqirha okanye indawo yezonyango.

Ugqirha wakho angalinciphisa idosi, alibazise okanye ayeke unyango lwakho ngenaliti ye-moxetumomab pasudotox-tdfk, okanye akuncede ngamayeza ongezelelweyo ngokuxhomekeke kwimpendulo yakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-moxetumomab pasudotox-tdfk,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-moxetumomab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-moxetumomab pasudotox-tdfk injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha uneengxaki zonyango.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Uya kudinga ukuba ube novavanyo lokukhulelwa ngaphambi kokuba uqale i-moxetumomab. Akufanele ukhulelwe ngelixa ufumana inaliti ye-moxetumomab pasudotox-tdfk kwaye ubuncinci kwiintsuku ezingama-30 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa ufumana inaliti ye-moxetumomab pasudotox-tdfk, tsalela umnxeba kwangoko. Inaliti ye-Moxetumomab pasudotox-tdfk inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa okanye ucwangcisa ukuncancisa.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphoswa idinga lokufumana ukunyuswa, biza ugqirha wakho ngokukhawuleza ukuba ubeke kwakhona ukuqeshwa kwakho.

Inaliti ye-Moxetumomab pasudotox-tdfk inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhina
• ulusu oluthuthu
• ukudinwa
• iso elomileyo okanye iintlungu zamehlo
• ukudumba kwamehlo okanye usulelo
• utshintsho lombono

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO okanye INDLELA yamacandelo, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• izihlunu; ukuba ndindisholo okanye ukurhawuzelela; ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo; isicaphucaphu; okanye ukuxhuzula

Inaliti ye-Moxetumomab pasudotox-tdfk inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-moxetumomab pasudotox-tdfk.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Lumoxiti^®