Alpelisib

Umxholo

• Ngaphambi kokuba uthathe i-alpelisib,
• I-Alpelisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Alpelisib isetyenziswa ngokudibene ne-fulvestrant (Faslodex) ukunyanga uhlobo oluthile lomhlaza wamabele osasazeke kwizicubu ezikufuphi okanye amanye amalungu omzimba kubafazi abasele beyekile ukuya exesheni ('' utshintsho lobomi, '' ukuphela kokuya exesheni period) okanye emadodeni, onesifo somhlaza esiba mandundu ngexesha okanye emva kolunye unyango. U-Alpelisib ukwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela imiqondiso ebangela ukuba iiseli zomhlaza zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

IAlpelisib iza njengecwecwe lokuthatha ngomlomo. Kuhlala kuthathwa kunye nokutya kube kanye ngemini ukuba ugqirha ucebisa unyango. Thatha i-alpelisib malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-alpelisib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Musa ukuthatha ithebhulethi eyaphukileyo, eqhekekileyo okanye eyonakeleyo.

Ukuba uyagabha emva kokuthatha i-alpelisib, musa ukuthatha elinye idosi. Qhubeka neshedyuli yakho yesiqhelo.

Ugqirha wakho unokunciphisa idosi yealpelisib, ukunyanga ngamanye amayeza, okanye ukuphazamisa okanye uyeke unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho kunye ne-alpelisib.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-alpelisib,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-alpelisib, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi ze-alpelisib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, okanye izongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qinisekisa ukukhankanya nayiphi na kwezi zilandelayo: carbamazepine (Carbatrol, Equetro, Tegretol, abanye), cyclosporine (Gengraf, Neoral, Sandimmune), efavirenz (Sustiva, eAtripla, Symfi), eltrombopag (Promacta), nevirapine (Viramune), phenobarbital , phenytoin (Dilantin, Phenytek), pioglitazone (Actos, eOseni, Duetact), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, eRifamate, Rifater), kunye warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-alpelisib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi i-curcumin kunye neSt.
• xelela ugqirha wakho ukuba wakha wanerhashalala enezilonda ezibomvu emilebeni, emlonyeni okanye eluswini, okanye ukuphalaza, ulusu oludumbileyo; okanye unesifo seswekile okanye isifo sezintso.
• xelela ugqirha wakho ukuba wena okanye iqabane lakho ukhulelwe, okanye ucwangcise ukukhulelwa. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngexesha lonyango lwakho kunye ne-alpelisib. Ukuba ungowasetyhini onokukhulelwa, kuya kufuneka ukuba ube novavanyo lokukhulelwa ngaphambi kokuba uqale unyango, kwaye kuya kufuneka usebenzise ulawulo lokuzalwa ngexesha lonyango lwakho kunye neveki e-1 emva kwedosi yakho yokugqibela. Ukuba uyindoda eneqabane lomfazi elinokukhulelwa, sebenzisa ikhondom ngexesha lonyango lwakho kunye neveki e-1 emva kwedosi yakho yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha i-alpelisib, biza ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho unokukuxelela ukuba ungancancisi ngexesha lokunyanga kunye nakwiveki e-1 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha i-alpelisib.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba ngaphezulu kweeyure ezili-9 kudlule ukusukela idosi ephosiweyo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Alpelisib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukudinwa kakhulu
• ukunciphisa ukutya
• utshintsho kwindlela izinto ezingcamla ngayo
• ukuhla ukusinda
• intlungu zesisu
• isilungulela
• ukulahleka kweenwele
• intloko ebuhlungu
• ukurhawuzelela
• isikhumba esomileyo
• umlomo owomileyo
• ukoma kwilungu lobufazi
• ifiva
• ukudumba kweengalo okanye imilenze

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ingxaki yokuginya okanye ukuphefumla, irhashalala, ukugungxula, umkhuhlane okanye ukubetha kwentliziyo okukhawulezayo
• Ukuqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqhaqha, isikhumba esibomvu, izilonda emlonyeni okanye emlonyeni, umkhuhlane, iimpawu ezifana nomkhuhlane
• ukoma okunxaniweyo, umlomo owomileyo, ukwanda kwesidlo kunye nokwehla kobunzima, ukuchama rhoqo okanye izixa ezikhulu kunesiqhelo, umphefumlo onuka iziqhamo
• ukuphefumla kancinci, ukukhohlela, iintlungu esifubeni, ukuphefumla nzima
• urhudo oluqatha, umlomo owomileyo, iicramps, ubuthathaka, ukunciphisa ukuchama, ukudumba kwemilenze okanye amaqatha
• Ukuchama rhoqo, okubuhlungu, okanye okungxamisekileyo

I-Alpelisib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• isicaphucaphu
• ukunqongophala kwamandla
• irhashalala
• ukwanda kokoma kunye nokutya
• umlomo owomileyo
• Ukuchama rhoqo okanye izixa ezikhulu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba ngaba umhlaza wakho unganyangwa na nge-alpelisib. Ugqirha wakho uya ku-odola iimvavanyo ezithile zelebhu ngaphambi kwaye ngexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-alpelisib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UPiqray^®