Sacituzumab govitecan-hziy Inaliti

Umxholo

• Phambi kokufumana i-sacituzumab govitecan-hziy,
• I-Sacituzumab govitecan-hziy inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO KANYE NAMANQAKU, fowunela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Sacituzumab govitecan-hziy inokubangela ukwehla okumandla kwenani leeseli ezimhlophe egazini. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu rhoqo ngexesha lonyango lwakho ukujonga inani leeseli ezimhlophe egazini lakho. Ukuhla kwenani leeseli ezimhlophe emzimbeni wakho kunokunyusa umngcipheko wokuba ube nosulelo olubi. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umkhuhlane, ukugodola, umqala obuhlungu, ukuphefumla kancinci, ukukhohlela okuqhubekayo kunye nokudibana, ukutshisa okanye iintlungu xa uchama, okanye ezinye iimpawu zosulelo.

I-Sacituzumab govitecan-hziy inokubangela urhudo oluqatha. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko kugqirha: izitulo ezikhululekileyo; urhudo; ilindle emnyama okanye egazini; iimpawu zokuphelelwa ngamanzi emzimbeni njengobunzima bentloko, isiyezi, okanye ukudinwa; okanye ukuba awukwazi ukuthatha ulwelo ngomlomo ngenxa yesicefecefe okanye ukugabha. Thetha nogqirha wakho malunga nento ekufuneka uyenzile ukuba uluhambisa urhudo nangaliphi na ixesha kunyango lwakho nge-sacituzumab govitecan-hziy okanye ukuba alulawulwa kwisithuba seeyure ezingama-24 emva konyango ngamayeza orhudo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-sacituzumab govitecan-hziy.

Thetha nogqirha wakho malunga nemingcipheko yokufumana isakituzumab govitecan-hziy.

I-Sacituzumab govitecan-hziy isetyenziselwa ukunyanga uhlobo oluthile lomhlaza wamabele kubantu abadala abathe banwenwela kwamanye amalungu omzimba kwaye sele bephethwe ubuncinci ngamanye amayeza e-chemotherapy. I-Sacituzumab govitecan-hziy ikudidi lwamayeza abizwa ngokuba ngama-anti-drug conjugates. Isebenza ngokubulala iiseli zomhlaza.

ISacituzumab govitecan-hziy iza njengomgubo oxutywe nolwelo kwaye itofwe ngaphakathi (emthanjeni) ngaphezulu kwe-1 ukuya kwiiyure ezi-3 ngugqirha okanye umongikazi esibhedlele okanye kwiziko lonyango. Ihlala inikwa ngeentsuku zoku-1 kunye ne-8 zomjikelo weentsuku ezingama-21. Umjikelo unokuphindwa njengoko ucetyiswa ngugqirha wakho. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango kunye naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo.

I-Sacituzumab govitecan-hziy inaliti inokubangela isicaphucaphu, ukugabha, kunye nokuphazamiseka okunzulu, okuhlala kwenzeka ngexesha lokufakwa kweyeza okanye kwiiyure ezingama-24 zokufumana idosi. Uya kunikwa amanye amayeza ukunceda ukuthintela nokunyanga iimpendulo. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngexesha kunye nemizuzu engama-30 ubuncinci emva kokufakwa kulo naluphi na unyango. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: isicaphucaphu; ukugabha; ukudumba kobuso bakho, imilebe, ulwimi, okanye umqala; ifiva; isiyezi; ukugungxula; Ukugodola; irhashalala; imihlathi ukurhawuzelela; ukuvutha; okanye ubunzima bokuphefumla.

Ugqirha wakho unokunciphisa idosi yakho okanye ayeke unyango lwakho okwethutyana okanye ngokusisigxina. Oku kuxhomekeke ekusebenzeni kakuhle kweyeza kunye neziphumo ebezingalindelekanga ohlangabezana nazo. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho kunye ne-sacituzumab govitecan-hziy.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana i-sacituzumab govitecan-hziy,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-sacituzumab govitecan-hziy, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-sacituzumab govitecan-hziy injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: carbamazepine (Carbatrol, Equetro, Teril, others), atazanavir (Reyataz, e-Evotaz), indinavir (Crixivan), irinotecan (Camptosar, Onivyde), phenobarbital, rifampin (Rifadin, in Rifater), kunye ne-sorafenib (Nexavar). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye ukuba ucwangcisa ukuba notata umntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana inaliti ye-sacituzumab govitecan-hziy. Ukuba ungumfazi okwaziyo ukukhulelwa, kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango kwaye usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwethamo lakho lokugqibela. Ukuba uyindoda, wena neqabane lakho labasetyhini kufuneka nisebenzise ulawulo lokuzalwa ngexesha lonyango kunye nakwiinyanga ezi-3 emva kwedosi yokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana inaliti ye-sacituzumab govitecan-hziy, tsalela ugqirha wakho. I-Sacituzumab govitecan-hziy inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanelanga ukuncancisa ngelixa ufumana i-sacituzumab govitecan-hziy kunye nenyanga e-1 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma kubafazi. Thetha nogqirha wakho malunga nemingcipheko yokufumana i-sacituzumab govitecan-hziy.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphoswa idinga lokufumana i-sacituzumab govitecan-hziy, tsalela ugqirha wakho kwangoko.

I-Sacituzumab govitecan-hziy inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukuqhina
• izilonda zomlomo
• isisu esibuhlungu
• ukudinwa
• Ukuphelelwa ngumdla wokutya
• utshintsho lwencasa
• ukulahleka kweenwele
• isikhumba esomileyo
• intloko ebuhlungu
• intlungu, ukutshisa, okanye ukubetha ezandleni nasezinyaweni
• umqolo okanye iintlungu ezidibeneyo
• iintlungu ezingalweni okanye emilenzeni
• ukudumba kwezandla, amaqatha okanye iinyawo
• ubunzima bokulala okanye ukulala
• ulusu olukhanyayo okanye ukudinwa okungaqhelekanga okanye ubuthathaka

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO KANYE NAMANQAKU, fowunela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukugruzuka okulula okanye ukopha; ukopha kwiintsini okanye empumlweni; okanye igazi kumchamo okanye isitulo

I-Sacituzumab govitecan-hziy inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• umkhuhlane, ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga ne-sacituzumab govitecan-hziy. Ugqirha wakho unoku-odola iimvavanyo ezithile zelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba kunokwenzeka ukuba ube nomngcipheko owandileyo weziphumo ebezingalindelekanga ezivela kwi-sacituzumab govitecan-hziy esekwe kwilifa lakho okanye ukwakheka kwemfuza.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuhamba^®