Inaliti ye-Bamlanivimab kunye ne-Etesevimab

Umxholo

• Phambi kokufumana i-bamlanivimab kunye nenaliti ye-etesevimab,
• I-Bamlanivimab kunye ne-etesevimab inaliti inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-HOW, tsalela umnxeba kwangoko okanye ufumane unyango lonyango:

Indibaniselwano ye-bamlanivimab kunye nenaliti ye-etesevimab kungoku nje ifundelwa unyango lwe-coronavirus isifo se-2019 (COVID-19) ebangelwa yintsholongwane ye-SARS-CoV-2.

Ulwazi olulinganiselweyo lwezonyango olufumanekayo ngeli xesha lokuxhasa ukusetyenziswa kwe-bamlanivimab kunye ne-etesevimab kunyango lwe-COVID-19. Ulwazi oluthe kratya luyafuneka ukwazi ukuba isebenza njani i-bamlanivimab kunye ne-etesevimab kunyango lwe-COVID-19 kunye neziganeko ezimbi ezinokubakho kuyo.

Indibaniselwano ye-bamlanivimab kunye ne-etesevimab khange iphonononge umgangatho ukuze yamkelwe yi-FDA ukuze isetyenziswe. Nangona kunjalo, i-FDA ivume iSigunyaziso sokuSetyenziswa ngokuNgxamisekileyo (i-EUA) ukuvumela abantu abadala abangalaliswanga esibhedlele kunye nabantwana abaneminyaka eli-12 ubudala nangaphezulu abaneempawu ezithandekayo zokumodareyitha ze-COVID-19 zokufumana inaliti ye-bamlanivimab kunye ne-etesevimab.

Indibaniselwano ye-bamlanivimab kunye nenaliti ye-etesevimab isetyenziselwa ukunyanga usulelo lwe-COVID-19 kubantu abadala abangalaliswanga esibhedlele kunye nabantwana abaneminyaka eli-12 ubudala nangaphezulu abanobunzima obungama-88 eekhilogram (40 kg) nabaneempawu ezithandekayo zokumodareyitha ze-COVID-19. Zisetyenziselwa abantu abaneemeko ezithile zonyango ezinje ngesifo seswekile, iimeko zokuzikhusela emzimbeni, okanye izintso, intliziyo, okanye isifo semiphunga ezibabeka emngciphekweni omkhulu wokukhula kweempawu ezinzima ze-COVID-19 kunye / okanye abafuna ukulaliswa esibhedlele kwi-COVID-19. I-Bamlanivimab kunye ne-etesevimab bakwiklasi ebizwa ngokuba yi-monoclonal antibodies. La mayeza asebenza ngokuthintela isenzo sento ethile yendalo emzimbeni ukunqanda ukusasazeka kwentsholongwane.

I-Bamlanivimab kunye ne-etesevimab ziza njengezisombululo (ulwelo) oluza kudityaniswa kunye nolwelo olongezelelekileyo emva koko bujojwe kancinci emthanjeni ngugqirha okanye ngumongikazi. Banikwa kunye njengedosi yexesha elinye ngokukhawuleza emva kovavanyo oluqinisekileyo lwe-COVID-19 kwaye kwiintsuku ezili-10 emva kokuqala kweempawu zokusuleleka ze-COVID-19 ezinje ngomkhuhlane, ukukhohlela, okanye ukuphefumla kancinci.

Ukudityaniswa kwe-bamlanivimab kunye ne-etesevimab inaliti kunokubangela ukusabela okunobuzaza okanye okusongela ubomi ngexesha nasemva kokufakwa. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngelixa ufumana la mayeza kwaye ubuncinci iyure emva kokuba uwafumene. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva kokufakwa: ifiva, ubunzima bokuphefumla, ukugodola, ukudinwa, iintlungu esifubeni, ukungonwabi esifubeni, ubuthathaka, ukudideka, isicaphucaphu, isicaphucaphu, intloko ebuhlungu, ukuphefumla kancinci, ukuvutha, umqala ukucaphuka, irhashalala, urhashalala, ukurhawuzelela, ukugungxula, iintlungu zemisipha okanye isiyezi, ngakumbi xa umile, ukubila, okanye ukudumba kobuso, umqala, ulwimi, imilebe okanye amehlo. Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho okanye ayeke unyango lwakho ukuba unazo naziphi na iziphumo ebezingalindelekanga.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Phambi kokufumana i-bamlanivimab kunye nenaliti ye-etesevimab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-bamlanivimab, i-etesevimab, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-bamlanivimab kunye ne-etesevimab injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza e-immunosuppressive anjenge cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, kunye ne tacrolimus (Astagraf, Envarsus, Prograf). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha naziphi na iimeko zonyango.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana i-bamlanivimab kunye ne-etesevimab inaliti, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Bamlanivimab kunye ne-etesevimab inaliti inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukopha, ukugruzuka, iintlungu, ukukhathazeka, okanye ukudumba kwindawo yenaliti

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-HOW, tsalela umnxeba kwangoko okanye ufumane unyango lonyango:

• umkhuhlane, ubunzima bokuphefumla, utshintsho kwiqondo lentliziyo, ukudinwa, ubuthathaka, okanye ukudideka

I-Bamlanivimab kunye ne-etesevimab inaliti inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana la mayeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga ne-bamlanivimab kunye nenaliti ye-etesevimab.

Kuya kufuneka uqhubeke nokuzahlula ngokokuyalelwa ngugqirha wakho kwaye ulandele iinkqubo zempilo zikawonkewonke ezinje ngokunxiba imaski, ukudibanisa ekuhlaleni, kunye nokuhlamba izandla rhoqo.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

Umbutho waseMelika woNyango lwezeMpilo-i-Pharmacists, Inc.mele ukuba olu lwazi malunga ne-bamlanivimab kunye ne-etesevimab lwenziwa ngomgangatho ofanelekileyo wokhathalelo, nangokuhambelana nemigangatho yobungcali ebaleni. Abafundi bayalunyukiswa ukuba i-bamlanivimab kunye ne-etesevimab ayilulo unyango oluvunyiweyo lwesifo se-coronavirus 2019 (i-COVID-19) ebangelwa yi-SARS-CoV-2, kodwa endaweni yoko, iyaphandwa kwaye ngoku iyafumaneka phantsi, isigunyaziso sokusetyenziswa okungxamisekileyo kwe-FDA (EUA) kunyango lwe-COVID-19 ethambileyo ukuya kwelinganiselweyo kwizigulana ezithile. Umbutho waseMelika woNyango lwezeMpilo-iiNkqubo zooSokhemisti, Inc. ayenzi bume okanye ziqinisekiso, zichaza okanye zichaziweyo, kubandakanya, kodwa kungaphelelanga apho, nakweyiphi na iwaranti echaziweyo yokurhweba kunye / okanye ukufaneleka kwinjongo ethile, ngokubhekisele kulwazi, ngakumbi iyazichaza zonke ezi ziqinisekiso. Abafundi bolwazi malunga ne-bamlanivimab kunye ne-etesevimab bayacetyiswa ukuba i-ASHP ayinaxanduva lwemali eqhubekayo yolwazi, ngazo naziphi na iimpazamo okanye ukushiywa, kunye / okanye naziphi na iziphumo ezibangelwe kukusetyenziswa kolwazi. Abafundi bayacetyiswa ukuba izigqibo ngokubhekisele kunyango lweziyobisi zizigqibo ezintsonkothileyo zonyango ezifuna isigqibo esizimeleyo, esichaziweyo sengcali efanelekileyo yokhathalelo lwempilo, kwaye ulwazi oluqulethwe kolu lwazi lubonelelwa ngeenjongo zolwazi kuphela. I-American Society ye-Health-System Pharmacists, Inc. ayikhuthazi okanye icebise ukusetyenziswa kwalo naliphi na ichiza. Olu lwazi malunga ne-bamlanivimab kunye ne-etesevimab akufuneki ukuba luqwalaselwe njengengcebiso yesigulana. Ngenxa yokutshintsha kolwazi lweziyobisi, uyacetyiswa ukuba ubonane nogqirha wakho okanye usokhemesti malunga nokusetyenziswa kweeklinikhi ezithile kunye nawo onke amayeza.