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USMLE: Medical Video Lectures Pharmacology about Cytarabine by UsmleTeam
Ividiyo: USMLE: Medical Video Lectures Pharmacology about Cytarabine by UsmleTeam

Umxholo

Inaliti yeCytarabine kufuneka inikezwe phantsi kweliso likagqirha onamava ekunikeni amayeza e-chemotherapy kumhlaza.

I-Cytarbine inokubangela ukwehla okukhulu kwinani leeseli zegazi kumongo wethambo lakho. Oku kunokubangela iimpawu ezithile kwaye kunokunyusa umngcipheko wokuba ube nosulelo olubi okanye ukopha. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: umkhuhlane, umqala obuhlungu, ukukhohlela okuqhubekayo nokuxinana, okanye ezinye iimpawu zosulelo; ukopha okungaqhelekanga okanye ukugruzuka; izitulo ezimnyama nezokulinda; igazi elibomvu ilindle; ukugabha kwegazi; Izinto ezigabileyo ezibonakala ngathi ziindawo zekofu.

I-Cytarabine isetyenziswa yodwa okanye nezinye iziyobisi ze-chemotherapy ukunyanga iintlobo ezithile ze-leukemia (umhlaza weeseli ezimhlophe zegazi), kubandakanya i-acute myeloid leukemia (AML), i-acety lymphocytic leukemia (YONKE), kunye ne-leukemia engapheliyo (CML) I-Cytarabine ikwasetyenziswa yodwa okanye nezinye iziyobisi ze-chemotherapy ukunyanga i-leukemia ye-meningeal (umhlaza kwi-membrane egubungela nokukhusela intambo yomqolo kunye nengqondo). I-Cytarabine ikwiklasi yamayeza abizwa ngokuba zii-antimetabolites. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.


I-Cytarabine iza njengomgubo oxutywe nolwelo oza kufakwa ngaphakathi (emthanjeni), ngaphantsi (ngaphantsi kolusu), okanye ngaphakathi (kwindawo egcwele ulwelo yomqolo womqolo) ngugqirha okanye ngumongikazi kwiziko lonyango. Ugqirha wakho uza kukuxelela ukuba uza kuyifumana kangaphi icytarabine. Ishedyuli ixhomekeke kwimeko onayo nakwindlela umzimba wakho uphendula ngayo kunyango.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

I-Cytarabine ngamanye amaxesha isetyenziselwa ukunyanga iintlobo ezithile ze-non-Hodgkin's lymphoma (uhlobo lomhlaza oluqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti yecytarabine,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-cytarabine okanye ezinye izithako kwi-cytarabine injection. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: digoxin (Lanoxin), flucytosine (Ancobon), okanye gentamicin. Amanye amayeza anokusebenzisana ne-cytarabine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
  • xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye sesibindi.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Akufanele ukhulelwe ngelixa ufumana inaliti yecytarabine. Ukuba ukhulelwa ngelixa ufumana i-cytarabine, tsalela ugqirha wakho. I-Cytarabine inokulimaza umbungu.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


I-Cytarabine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isicaphucaphu
  • ukugabha
  • urhudo
  • isisu esibuhlungu
  • Ukuphelelwa ngumdla wokutya
  • izilonda emlonyeni nasemqaleni
  • ukulahleka kweenwele
  • intlungu yesihlunu okanye edibeneyo
  • ukudinwa
  • amehlo abuhlungu okanye abomvu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

  • iintlungu eziqhubekayo eziqala kwindawo yesisu kodwa zinokusasazeka ngasemva
  • ububomvu, iintlungu, ukudumba, okanye ukutshisa kwindawo enikwe inaliti
  • ulusu oluthuthu
  • isiqaqa
  • isiyezi
  • ukukhawuleza kwentliziyo okanye okungaqhelekanga
  • irhashalala
  • urhwebo
  • ukurhawuzelela
  • ubunzima bokuphefumla okanye ukugwinya
  • iintlungu zesifuba
  • mthubi ulusu okanye amehlo
  • umchamo omnyama-mnyama okanye ukuncipha kokuchama
  • ukuqhawukelwa ngumphefumlo
  • utshintsho olukhawulezileyo okanye ukulahleka kombono
  • ukuxhuzula
  • ukudideka
  • ukuba ndindisholo, ukutshisa, okanye ukurhawuzelela izandla, iingalo, iinyawo okanye imilenze

I-Cytarabine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya.Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • ICytosar-U®
  • 1-beta-Arabinofuranosylcytosine
  • IArabinosylcytosine
  • ICytosine arabinoside
  • IAra-C
Ukuhlaziywa kokugqibela-02/15/2012

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