Niacin

Umxholo

• I-Niacin isetyenziswa kutshintsho lokutya (isithintelo se-cholesterol kunye nokutya okunamafutha) ukunciphisa inani le-cholesterol (into efana ne-fat) kunye nezinye izinto ezinamafutha egazini lakho kunye nokunyusa inani le-lipoprotein ephezulu (HDL; '' cholesterol elungileyo ''). INiacin inokusetyenziswa kwiimeko ezininzi kubandakanya oku kulandelayo:
• Ngaphambi kokuba uthathe i-niacin,
• I-Niacin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Niacin isetyenziswa kutshintsho lokutya (isithintelo se-cholesterol kunye nokutya okunamafutha) ukunciphisa inani le-cholesterol (into efana ne-fat) kunye nezinye izinto ezinamafutha egazini lakho kunye nokunyusa inani le-lipoprotein ephezulu (HDL; '' cholesterol elungileyo ''). INiacin inokusetyenziswa kwiimeko ezininzi kubandakanya oku kulandelayo:

• yedwa okanye ngokudibanisa namanye amayeza, njenge-HMG-CoA inhibitors (i-statins) okanye i-bile acid-binding resins;
• ukunciphisa umngcipheko wesinye isifo sentliziyo kwizigulana ezine-cholesterol ephezulu ethe yahlaselwa sisifo sentliziyo;
• Ukuthintela ukwanda kwe-atherosclerosis (i-cholesterol eyongezelelekileyo kunye namafutha ecaleni kweendonga zemithambo yegazi) kwizigulana ezine-cholesterol ephezulu kunye nesifo semithambo;
• ukunciphisa inani le-triglycerides (ezinye izinto ezinamafutha) egazini kwizigulana ezine-triglycerides ephezulu ezisemngciphekweni wesifo se-pancreatic (iimeko ezichaphazela ipancreas, idlala elivelisa ulwelo lokuphula ukutya kunye neehomoni ukulawula iswekile yegazi).

I-Niacin ikwasetyenziselwa ukuthintela nokunyanga i-pellagra (ukusilela kwe-niacin), isifo esibangelwa kukungonelanga kokutya kunye nezinye iingxaki zonyango. I-Niacin yi-B-complex vitamin. Kwiidosi zonyango, i-niacin yonyango elinciphisa i-cholesterol.

Iziphumo zophononongo lweklinikhi kubantu abanesifo sentliziyo kunye namanqanaba e-cholesterol alawulwa kakuhle athelekisa abantu abathathe i-niacin kunye ne-simvastatin nabantu abathathe i-simvastatin bodwa kwaye bafumana iziphumo ezifanayo kula maqela mabini kwinqanaba lokuhlaselwa kwentliziyo okanye ukubetha. Ukuthatha i-niacin kunye ne-simvastatin okanye i-lovastatin nayo ayiboniswanga ukunciphisa umngcipheko wesifo sentliziyo okanye ukufa xa kuthelekiswa nokusetyenziswa kwe-niacin, simvastatin, okanye i-lovastatin kuphela. Thetha nogqirha wakho ukuba unemibuzo malunga nobungozi kunye nezibonelelo zokunyusa inani le-cholesterol egazini lakho kunye ne-niacin kunye namanye amayeza.

I-Niacin iza njengecwecwe kunye nokukhutshelwa okwandisiweyo (ukusebenza ixesha elide) ukuthatha ngomlomo. Ithebhulethi yesiqhelo ihlala ithathwa kabini kathathu ngemini kunye nokutya, kwaye ithebhulethi ekhutshiweyo iyathathwa kanye ngemini, ngexesha lokulala, emva kwesidlo esinamafutha asezantsi. Landela umkhombandlela kwileyibhile yakho yeleta okanye iphakheji yelebhile ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze naliphi na icandelo ongaliqondiyo. Thatha i-niacin ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi zokukhululwa ezandisiweyo; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-niacin kwaye ngokuthe ngcembe andise idosi yakho.

Qhubeka nokuthatha i-niacin nokuba uziva uphilile. Ungayeki ukuthatha i-niacin ngaphandle kokuthetha nogqirha wakho.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-niacin,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-niacin, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-niacin. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-anticoagulants ('i-blood thinner') efana ne-warfarin (Coumadin); iasprini; i-insulin okanye amayeza omlomo eswekile; amayeza kuxinzelelo lwegazi; izongezo zesondlo okanye ezinye iimveliso eziqukethe i-niacin; okanye amanye amayeza okunciphisa i-cholesterol okanye i-triglycerides. Ukuba uthatha i-insulin okanye iyeza leswekile yomlomo, idosi yakho inokufuna ukuba itshintshwe kuba i-niacin inokunyusa inani leswekile egazini nasemchameni.
• ukuba uthatha i-bile acid-binding resin efana necolestipol (Colestid) okanye cholestyramine (Questran), thatha okungenani iiyure ezi-4 ukuya kwezi-6 ngaphambi okanye kwiiyure ezi-4 ukuya kwezi-6 emva kwe-niacin.
• xelela ugqirha wakho ukuba usela utywala kakhulu kwaye ukhe unesifo seswekile; igawuthi; izilonda; ukwaliwa; i-jaundice (ukutyheli kolusu okanye amehlo); iingxaki zokopha; okanye inyongo, intliziyo, izintso, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-niacin, yeka ukuthatha i-niacin kwaye ubize ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-niacin.
• buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa uthatha i-niacin. Utywala bungenza iziphumo ebezingalindelekanga zibe mbi nangakumbi.
• Kuya kufuneka uyazi ukuba i-niacin ibangela ukugungxula (ubomvu, ukufudumala, ukurhawuzelela, ukubetha) kobuso, intamo, isifuba, okanye umqolo. Iziphumo ebezingalindelekanga zihlala zihamba emva kokuthatha iyeza iiveki ezimbalwa. Kulumkele ukusela utywala okanye iziselo ezishushu okanye ukutya ukutya okunezipayisi malunga nexesha olithathayo. Ukuthatha i-aspirin okanye elinye ichiza elichasayo elichasayo njenge-ibuprofen (Advil, Motrin) okanye naproxen (Aleve, Naprosyn) imizuzu engama-30 ngaphambi kokuba i-niacin inciphise ukugungxula. Ukuba uthatha i-niacin ekhutshiweyo eyandisiweyo ngexesha lokulala, ukugungxulwa kuya kwenzeka ngelixa ulele. Ukuba uvuka kwaye uzive uhlaziyekile, vuka kancinci, ngakumbi ukuba uziva unesiyezi okanye ufe isiqaqa.

Yitya ukutya okune-fat-fat, low-cholesterol. Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Ungandwendwela iNational Cholesterol Education Programme (NCEP) kwiwebhusayithi ukufumana ulwazi olongezelelekileyo malunga nokutya kule http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ukuba uyeka ukuthatha i-niacin ngalo naliphi na ubude bexesha, tsalela ugqirha ngaphambi kokuba uphinde uthathe kwakhona.

I-Niacin inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• ukwanda ukhohlokhohlo

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• isiyezi
• ukudinwa
• ukubetha kwentliziyo ngokukhawuleza
• isicaphucaphu
• ukugabha
• ukudinwa kakhulu
• umchamo omnyama ngombala
• izitulo ezikhanyayo
• ukopha okungaqhelekanga okanye ukugruzuka
• ukunqongophala kwamandla
• Ukuphelelwa ngumdla wokutya
• iintlungu kwinxalenye ephezulu yesisu
• mthubi ulusu okanye amehlo
• Iimpawu ezinjengomkhuhlane
• urhwebo
• irhashalala
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• Iintlungu zemisipha ezingachazwanga, ukuthamba, okanye ubuthathaka

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya ku-odola iimvavanyo ezithile zebhu ukujonga impendulo yakho kwi-niacin.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha i-niacin.

Sebenzisa kuphela uphawu kunye nohlobo lwe-niacin oluyalelwe ngugqirha wakho. Sukusebenzisa olunye uhlobo lwe-niacin okanye utshintshe phakathi kweemveliso ngaphandle kokuthetha nogqirha wakho. Ukuba utshintshela kuhlobo olwahlukileyo okanye uhlobo lwe-niacin, idosi yakho inokufuna ukuba itshintshwe.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Niacor^®
• Niaspan^®
• Nicolar^®¶
• ISlo-Niacin^®

• Simcor^® (iqulethe iNiacin, iSimvastatin)

• Nicotinic acid

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.