Inaliti ye-Interferon Alfa-2b

Umxholo

• Inaliti ye-Interferon alfa-2b iyasetyenziswa
• Ukuba unayo:
• Ngaphambi kokufumana inaliti ye-interferon alfa-2b,
• Inaliti ye-Interferon alfa-2b inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye naziphi na okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO okanye kumacandelo okhuseleko, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

Inaliti ye-Interferon alfa-2b inokubangela okanye yenze mandundu le miba ilandelayo enokuba nobuzaza okanye isongele ubomi: usulelo; ukugula ngengqondo, kubandakanya ukudakumba, iingxaki zemood kunye nokuziphatha, okanye iingcinga zokuzenzakalisa okanye ukuzibulala okanye ukubulala abanye; ukuphazamiseka kweschemic (iimeko apho ukungabikho kwegazi kwindawo efanelekileyo emzimbeni) njenge-angina (iintlungu zesifuba) okanye isifo sentliziyo; kunye nokuphazamiseka komzimba (iimeko apho amajoni omzimba ahlasela elinye okanye ngaphezulu amalungu omzimba anokuchaphazela igazi, amalungu, izintso, isibindi, imiphunga, izihlunu, ulusu, okanye idlala lengqula). Tshela ugqirha wakho ukuba unentsholongwane; okanye ukuba unesifo sokuzimela komzimba, ukhwekhwe (isifo esikhumbeni apho umbala obomvu, onamaxolo wenza iindawo ezithile zomzimba), inkquboic lupus erythematosus (SLE okanye lupus; isifo sokuzimela komzimba apho amajoni omzimba ahlasela esempilweni amalungu omzimba), i-sarcoidosis (imeko apho iiseli ezincinci zamajoni omzimba ezenza kumalungu ahlukeneyo anje ngemiphunga, amehlo, ulusu, nentliziyo kunye nokuphazamisa ukusebenza kwala malungu), okanye isifo samathambo (RA; imeko) apho umzimba uhlasela amalungu awo, ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi); umhlaza; isifo sokudumba (ukudumba amathumbu); isifo seswekile; ukuhlaselwa yintliziyo; igazi elonyukayo; amanqanaba aphezulu e-triglyceride (amafutha ahambelana ne-cholesterol); Intsholongwane kaGawulayo (intsholongwane yokungakhuseleki komzimba) okanye i-AIDS (i-immunodeficiency syndrome) ukubetha kwentliziyo ngokungaqhelekanga; ukugula ngengqondo kubandakanya ukudakumba, ixhala, okanye ukucinga okanye ukuzama ukuzibulala; okanye intliziyo, izintso, i-pancreas, okanye isifo se-thyroid.

Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko kugqirha: urhudo olunegazi okanye ukuhamba kwamathumbu; umkhuhlane, ukugodola, ukukhohlela nge-phlegm (mucus), umqala obuhlungu, okanye ezinye iimpawu zosulelo; ukuchama rhoqo okanye ngeentlungu, iintlungu zesifuba; ukubetha kwentliziyo ngokungaqhelekanga; utshintsho kwiimvakalelo zakho okanye kwindlela oziphatha ngayo; ukudakumba; ukuqala ukusebenzisa iziyobisi zasesitalatweni okanye utywala kwakhona ukuba ubukhe wazisebenzisa ngaphambili; ukucaphuka (ukucaphuka msinya); iingcinga zokuzibulala okanye ukuzenzakalisa; ubundlongondlongo okanye ubundlobongela; ubunzima bokuphefumla; iintlungu zesifuba; utshintsho ekuhambeni okanye kwintetho; ukunciphisa amandla okanye ubuthathaka kwelinye icala lomzimba wakho; ukungaboni kakuhle okanye ukulahleka kombono; isisu esibuhlungu; ukopha okungaqhelekanga okanye ukugruzuka; umchamo omnyama; ukukhanya kwemibala yokuhamba kwamathumbu; okanye ukwanda kwesifo somzimba.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-interferon alfa-2b.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-interferon alfa-2b kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Inaliti ye-Interferon alfa-2b isetyenziselwa ukunyanga iimeko ezininzi.

Inaliti ye-Interferon alfa-2b iyasetyenziswa

• iyodwa okanye idityaniswe ne-ribavirin (iCopegus, iRebetol, iRibasphere) ukunyanga usulelo lwe-hepatitis C olungapheliyo (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu ababonisa iimpawu zomonakalo wesibindi,
• ukunyanga usulelo lwe-hepatitis B engapheliyo (ukudumba kwesibindi okubangelwa yintsholongwane) kubantu ababonisa iimpawu zomonakalo wesibindi,
• ukunyanga i-leukemia yeseli enoboya (umhlaza weseli emhlophe),
• ukunyanga iintsumpa zangasese,
• ukunyanga i-Kaposi's sarcoma (uhlobo lomhlaza olwenza ukuba izicwili ezingaqhelekanga zikhule kwiindawo ezahlukeneyo zomzimba) ezinxulumene ne-immunodeficiency syndrome (i-AIDS),
• ukunyanga imelanoma ebulalayo (umhlaza oqala kwiiseli ezithile zolusu) kubantu abathile abaye batyandwa ukuze basuse umhlaza,
• Kunye namanye amayeza okunyanga i-lymphoma engeyo-Hodgkin's lymphoma (NHL; umhlaza wegazi okhula kancinci).

I-Interferon alfa-2b ikwiklasi yamayeza abizwa ngokuba zii-immunomodulators. I-Interferon alfa-2b isebenza ukunyanga intsholongwane ye-hepatitis C (HCV) kunye ne-hepatitis B virus (HBV) ngokunciphisa inani lentsholongwane emzimbeni. I-Interferon alfa-2b ayinakho ukunyanga i-hepatitis B okanye i-hepatitis C okanye ikuthintele ekuphuhliseni iingxaki kwezi zifo ezifana ne-cirrhosis (scarring) yesibindi, ukusilela kwesibindi, okanye umhlaza wesibindi. Kananjalo ayinakuthintela ukusasazeka kwe-hepatitis B okanye i-C kwabanye abantu. Ayaziwa ngokuthe ngqo ukuba i-interferon alfa-2b isebenza njani ukunyanga umhlaza okanye iintsumpa zangasese.

I-Interferon alfa-2b iza njengomgubo kwisitya sokudibanisa nolwelo kunye nesisombululo sokujova nokuba kungaphantsi (nje phantsi kolusu), intramuscularly (in a muscle), intravenous (in the vein), or intralesionally (in a lesion ). Kungcono ukutofa iyeza ngexesha elifanayo losuku kwiintsuku zakho zenaliti, zihlala emva kwemini okanye ngokuhlwa.

Ukuba unayo:

• I-HCV, yiza inaliti amayeza ngokunqamleza okanye entramuscular kathathu ngeveki.
• I-HBV, itofe iyeza ngokunqamlezayo okanye intramuscularly kathathu ngeveki ihlala iiveki ezili-16.
• I-leukemia eneseli enoboya, jofa iyeza nokuba litofelwe kwimisipha okanye ngokungaphantsi kathathu ngeveki ukuya kuthi ga kwiinyanga ezi-6.
• I-melanoma enobungozi, itofa iyeza ngaphakathi kwiintsuku ezi-5 zilandelelana kangangeeveki ezi-4, emva koko kathathu ngeveki kangangeeveki ezingama-48.
• i-follicular melanoma, thetha iyeza kathathu ngeveki ukuya kwiinyanga ezili-18.
• iintsumpa zangasese, jofa iyeza ngenaliti kathathu ngeveki kwezinye iintsuku zeeveki ezi-3, emva koko unyango lungaqhubeka ukuya kuthi ga kwiiveki ezili-16.
• I-Kaposi's sarcoma, ngenisa iyeza nokuba kungaphantsi okanye intramuscularly kathathu ngeveki kangangeeveki ezili-16.

Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-interferon alfa-2b kanye njengoko kuyalelwe. Sukusebenzisa ngaphezulu okanye ngaphantsi kweli yeza okanye ulisebenzise rhoqo okanye ixesha elide kunokuba umiselwe ngugqirha.

Ugqirha wakho unokunciphisa idosi yakho ukuba unemiphumo emibi yeyeza. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho kwaye ubuze ugqirha wakho okanye usokhemesti ukuba unemibuzo malunga nenani lonyango ekufuneka ulisebenzisile.

Uya kufumana idosi yakho yokuqala ye-interferon alfa-2b kwiofisi kagqirha wakho. Emva koko, unokufaka i-interferon alfa-2b ngokwakho okanye ukuba umhlobo okanye isalamane sikunike iinaliti. Ngaphambi kokuba usebenzise i-interferon alfa-2b okokuqala ngqa, wena okanye umntu oza kunika inaliti kufuneka afunde ulwazi lomenzi wesigulana esiza nayo. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kufaka inaliti iyeza ukuba ungalitofa njani. Ukuba omnye umntu uza kukutofa iyeza, qiniseka ukuba uyayazi indlela yokuphepha iinaliti ngengozi.

Ukuba ujoba eli yeza ngokunganyanzelekanga, ngenisa i-interferon alfa-2b naphina kwindawo yesisu sakho, iingalo ezingaphezulu, okanye amathanga akho, ngaphandle kwaxa usinqeni sakho okanye ujikeleze inkaba yakho (iqhosha lesisu). Musa ukujova iyeza lakho kulusu olucaphukisayo, olunamanxeba, lubomvu, lusulelekile, okanye lunamanxeba.

Ukuba ujova eli chiza intramuscularly, injare interferon alfa-2b ezingalweni zakho ezingaphezulu, emathangeni, okanye kwindawo engaphandle yeempundu. Sukusebenzisa indawo enye amaxesha amabini elandelelana.Musa ukujova iyeza lakho kulusu olucaphukisayo, olunamanxeba, lubomvu, lusulelekile, okanye lunamanxeba.

Ukuba ujova la mayeza ngaphakathi, jofa ngqo embindini wesiseko sentsumpa.

Ungaze uphinde usebenzise iisirinji, iinaliti, okanye iibhotile ze-interferon alfa-2b. Lahla iinaliti ezisetyenzisiweyo kunye neesirinji kwisitya esinganyangekiyo, kwaye ulahle iibhotile ezisetyenzisiweyo zamayeza enkunkumeni. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Ngaphambi kokuba usebenzise i-interferon alfa-2b, jonga isisombululo kwi-vial. Iyeza kufuneka licace kwaye lingenazinto zidadayo. Jonga ibhotile ukuze uqiniseke ukuba akukho kuvuza kwaye ujonge umhla wokuphelelwa. Sukusebenzisa isisombululo ukuba siphelelwe lixesha, kunamafu, siqulathe amasuntswana, okanye sentsimbi evuzayo.

Kuya kufuneka uxube ibhotile enye ye-interferon alfa-2b ngexesha. Kungcono ukuxuba amayeza kanye phambi kokuba ucwangcise ukuwatofa. Nangona kunjalo, unokudibanisa amayeza kwangaphambili, uyigcine kwifriji, kwaye uyisebenzise ngaphakathi kweeyure ezingama-24. Qiniseka ukuba uthathe amayeza ngaphandle kwefriji kwaye uvumele ukuba kufike kubushushu begumbi ngaphambi kokuba uyijoje.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-interferon alfa-2b kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo.

I-Interferon alfa-2b ngamanye amaxesha isetyenziselwa ukunyanga intsholongwane ye-hepatitis D (i-HDV; ukudumba kwesibindi okubangelwa yintsholongwane), i-basal cell carcinoma (uhlobo lomhlaza wolusu), i-T-cell lymphomas (CTCL, uhlobo lomhlaza wolusu) ), kunye nomhlaza wezintso. Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-interferon alfa-2b,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa inaliti ye-interferon alfa-2b, amanye amayeza e-interferon alfa kubandakanya iPEG-interferon alfa-2b (i-PEG-Intron) kunye ne-PEG-interferon alfa-2a (Pegasys), nawaphi na amanye amayeza, i-albin, okanye nasiphi na esinye isithako kwiinaliti ye-interferon alfa-2b. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: telbivudine (Tyzeka), theophylline (Elixophyllin, Theo-24, Theochron), okanye i-zidovudine (Retrovir, e-Combivir, e-Trizivir). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unesifo esibi sesibindi okanye i-autoimmune hepatitis (imeko apho iiseli zamajoni omzimba zihlasela isibindi). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi inaliti ye-interferon alfa-2b.
• xelela ugqirha wakho okanye usokhemesti ukuba ukhe wafakelwa ilungu lomzimba (utyando ukubuyisela ilungu emzimbeni) kwaye uthatha amayeza okucinezela amajoni akho omzimba. Xelela ugqirha wakho ukuba ukhe wakha wanayo nayiphi na imiqathango ekhankanywe kwicandelo LESILUMKISO ESIBALULEKILEYO okanye enye yezi zinto zilandelayo: ianemia (iiseli ezibomvu zegazi) okanye iiseli ezimhlophe ezisezantsi, iingxaki zokopha okanye amahlwili egazi kubandakanya ne-pulmonary embolism ( I-PE; i-clot yegazi emiphungeni), isifo semiphunga esifana ne-pneumonia, i-pulmonary arterial hypertension (PAH; uxinzelelo lwegazi oluphezulu kwimithambo ephethe igazi ukuya emiphungeni, ibangela ukuphefumla okufutshane, isiyezi kunye nokudinwa), (COPD; iqela lezifo ezichaphazela imiphunga kunye neendlela zomoya), okanye iingxaki zamehlo.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana inaliti ye-interferon alfa-2b, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana i-interferon alfa-2b.
• Kuya kufuneka uyazi ukuba unokuba neempawu ezinje ngomkhuhlane njengentloko, ukubila, iintlungu zemisipha, kunye nokudinwa emva kokufumana inaliti. Ugqirha wakho unokukuxelela ukuba uthathe i-acetaminophen (iTylenol), iintlungu zekhawuntareni kunye nonyango lomkhuhlane ukunceda kwezi mpawu. Thetha nogqirha wakho ukuba ezi mpawu kunzima ukuzilawula okanye ziqine.

Lumka usele ulwelo olwaneleyo ngexesha lonyango lokuqala lwe-interferon alfa-2b.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa idosi ye-interferon alfa-2b inaliti, ngenisa idosi yakho ngokukhawuleza nje ukuba ukhumbule okanye ukwazi ukuyinika. Sukusebenzisa inaliti ye-interferon alfa-2b iintsuku ezimbini zilandelelana. Musa ukufaka idosi ephindwe kabini ukwenza idosi ephosiweyo. Biza ugqirha wakho ukuba uphose idosi kwaye unemibuzo malunga nokwenza.

Inaliti ye-Interferon alfa-2b inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukutyumza, ukopha, iintlungu, ukuba bomvu, ukudumba, okanye ukucaphuka kwindawo otofa kuyo i-interferon alfa-2b
• iintlungu zemisipha
• utshintsho kwisakhono sokungcamla
• ukulahleka kweenwele
• isiyezi
• umlomo owomileyo
• iingxaki zoxinaniso
• uziva ubanda okanye ushushu
• utshintsho lobunzima
• ulusu luyatshintsha

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye naziphi na okanye ezo zidweliswe KWISILUMKISO ESIBALULEKILEYO okanye kumacandelo okhuseleko, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ulusu luyaxobuka
• ukurhawuzelela
• ubunzima bokuphefumla okanye ukugwinya
• ukudumba kwamehlo, ubuso, umlomo, ulwimi, okanye umqala
• utshintsho kumbono
• isisu esibuhlungu, ukuthamba okanye ukudumba
• mthubi ulusu okanye amehlo
• ukudinwa kakhulu
• ukudideka
• urhudo
• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• umqolo obuhlungu
• ukulahleka kwengqondo
• ukuba ndindisholo, ukutshisa okanye ukubetha ezandleni okanye ezinyaweni

Inaliti ye-Interferon alfa-2b inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kwifriji, kodwa ungayiginyi. Emva kokuxutywa, sebenzisa ngokukhawuleza. Ingagcinwa kwifriji ukuya kuthi ga kwiiyure ezingama-24 emva kokuxubeka. Lahla naliphi na iyeza eliphelelwe lixesha okanye elingasafunekiyo. Thetha kumachiza wakho malunga nokulahla ngokufanelekileyo amayeza akho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Intsingiselo A^®