I-Anti-Smooth Antibody ye-Anti-Smooth (ASMA)

Umxholo

• Luyintoni uvavanyo lwe-anti-smooth muscle antibody (ASMA)?
• Ngokuzimela hepatitis
• Lwenziwa njani uvavanyo lokuchasana nezihlunu oluthambileyo?
• Ziziphi iingozi?
• Zithetha ntoni iziphumo zovavanyo?
• Iziphumo eziqhelekileyo
• Iziphumo ezingaqhelekanga

Luyintoni uvavanyo lwe-anti-smooth muscle antibody (ASMA)?

Uvavanyo oluchasene nokuthamba kwezihlunu (ASMA) lufumanisa izilwa-buhlungu ezihlasela izihlunu ezigudileyo. Olu vavanyo lufuna isampulu yegazi.

Amajoni akho omzimba afumana izinto ezibizwa ngokuba ziiantigen ezinokuba yingozi emzimbeni wakho.Iintsholongwane kunye neebhaktiriya zigqunywe ngama-antigen. Xa amajoni akho omzimba eyamkela i-antigen, enza iprotein ekuthiwa yi-antibody yokuyihlasela.

Zonke i-antibody zahlukile, kwaye nganye iyazikhusela kuhlobo olunye kuphela lwe-antigen. Ngamanye amaxesha umzimba wakho ngempazamo wenza ii-autoantibodies, ezizintsholongwane ezihlasela iiseli zomzimba wakho ezisempilweni. Ukuba umzimba wakho uqala ukuhlasela ngokwawo, unokuhlakulela ukuphazamiseka komzimba.

Uvavanyo lwe-ASMA lukhangela uhlobo olunye lwe-autoantibody ehlasela izihlunu ezigudileyo. Amachiza omzimba athomalalisa ubundlobongela afunyanwa kwizifo zesibindi ezizimela ngokwakho ezinje nge-primary biliary cholangitis kunye ne-autoimmune hepatitis (AIH).

Ngokuzimela hepatitis

Ukuba unesifo sesibindi esinganyangekiyo, kunokwenzeka ukuba umboneleli wakho wezempilo uza kwenza uvavanyo lwe-ASMA. Uvavanyo lunokunceda ekuchongeni ukuba ingaba unayo i-AIH esebenzayo.

Iintsholongwane zezona zinto zibangela isifo se-hepatitis kwihlabathi liphela. I-AIH yinto eyodwa. Olu hlobo lwesifo sesibindi lwenzeka xa amajoni akho omzimba ehlasela iiseli zesibindi. I-AIH yimeko engapheliyo kwaye inokubangela ukuba i-cirrhosis, okanye ukubola, kwesibindi kwaye ekugqibeleni ukusilela kwesibindi.

Iimpawu kunye neempawu ze-AIH zibandakanya:

• isibindi esandisiweyo, esibizwa ngokuba yi-hepatomegaly
• isisu esiswini, okanye ukudumba
• Ukuthamba ngaphezulu kwesibindi
• umchamo omnyama
• ilindle elinombala okhanyayo

Iimpawu ezongezelelweyo zibandakanya:

• ubumthubi besikhumba namehlo, okanye i-jaundice
• ukurhawuzelela
• ukudinwa
• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• intlungu edibeneyo
• ukungaphatheki kakuhle kwesisu
• irhashalala

Lwenziwa njani uvavanyo lokuchasana nezihlunu oluthambileyo?

Awudingi ukwenza nantoni na ukulungiselela uvavanyo lwe-ASMA.

Unokwenza uvavanyo lwenziwe apha:

• esibhedlele
• ikliniki
• elebhu

Ukwenza uvavanyo lwe-ASMA, ingcali yokhathalelo lwempilo iya kufumana isampuli yegazi kuwe.

Ngokwesiqhelo, unika isampulu yegazi ngale ndlela ilandelayo:

1. Ingcali yezempilo isonga ibhanti e-elastic ejikeleze ingalo yakho ephezulu. Oku kumisa ukuhamba kwegazi, kwenza imithambo yakho ibonakale ngakumbi, kwaye yenze kube lula ukufaka inaliti.
2. Emva kokuba befumene umthambo wakho, umsebenzi wezempilo uhlamba isikhumba sakho nge-antiseptic kwaye ufake inaliti enetyhubhu eqhotyoshelwe ukuqokelela igazi. Njengoko inaliti ingena, unokuziva ucinezelekile okanye uhlaba kancinci. Unokuba nobunzima obuncinci xa uqeqesho lwezempilo lubeka inaliti emthanjeni wakho.
3. Emva kokuba ubungcali buqokelele ngokwaneleyo igazi lakho, baya kususa ibhanti e-elastic engalweni yakho. Basusa inaliti kwaye babeke i-gauze okanye isiqwenga somqhaphu kwindawo yenaliti kwaye basebenzise uxinzelelo. Baya kukhusela i-gauze okanye ikotoni nge-bandage.

Emva kokuba inaliti isusiwe, unokuziva ubethwa sisiza. Abantu abaninzi abaziva nto kwaphela. Ukungahambi kakuhle kunqabile.

Ziziphi iingozi?

Uvavanyo lwe-ASMA lunomngcipheko omncinci. Kunokubakho isixa esincinci sokugruzuka kwindawo yenaliti. Ukufaka uxinzelelo kwindawo yokugqobhoza kangangemizuzu eliqela emva kokuba umsebenzi wezempilo esusa inaliti unokunciphisa ukugruzuka.

Abanye abantu banomngcipheko wokuba wophe ngokuqhubekayo emva kokuba ingcali isusile inaliti. Xelela umlawuli wovavanyo ukuba uthatha abacoci gazi okanye uneengxaki zokopha okanye ukujiya.

Kwiimeko ezinqabileyo emva kokuba unike isampuli yegazi, ukuvuvukala kwe-vein kungenzeka. Le meko yaziwa ngokuba yi-phlebitis. Ukuyinyanga, sebenzisa icompress eshushu amaxesha amaninzi ngemini.

Kwiimeko ezinqabileyo kakhulu, ukutsalwa kwegazi kunokubangela:

• ukopha kakhulu
• intloko elula okanye etyhafayo
• ihematoma, ekufumaneni kwegazi phantsi kolusu
• usulelo kwindawo yenaliti

Zithetha ntoni iziphumo zovavanyo?

Iziphumo eziqhelekileyo

Iziphumo eziqhelekileyo zithetha ukuba akukho ma-ASMA abalulekileyo afunyenwe kwigazi lakho. Iziphumo zinokuxelwa njengesihloko. I-titer engathandekiyo, okanye uluhlu oluqhelekileyo, ithathwa njenge-dilution engaphantsi kwe-1: 20.

Iziphumo ezingaqhelekanga

Amanqanaba afunyenweyo ee-ASMA axelwa njengesihloko.

Iziphumo ezintle ze-AMSA zingaphezulu okanye zilingana nohlaziyo lwe-1: 40.

Ngokuhambisana nesifo sesibindi sokuzimela, uvavanyo olubuya luhle kwi-ASMA lunakho ngenxa:

• usulelo lwe-hepatitis C engapheliyo
• mononucleosis esosulelayo
• eminye imihlaza

Uvavanyo lwe-F-actin antibody, ukongeza kuvavanyo lwe-ASMA, lunokuphucula ukubanakho ukubona i-hepatitis yokuzimela komzimba kwezinye iimeko.

Kuba iziphumo zovavanyo zifuna ukutolikwa, ngakumbi ngokunxulumene nolunye uvavanyo olunokuthi lwenziwe, kubalulekile ukuba uthethe nogqirha wakho malunga neziphumo zakho ezithile.

Ukuchongwa kwe-autoimmune hepatitis kuthetha ukuba amajoni akho omzimba ngempazamo enza izilwa-buhlungu ezihlasela iiseli ezisempilweni kwisibindi sakho.

Nabani na onokuthi abe ne-hepatitis yokuzimela, kodwa ixhaphake kakhulu kubafazi kunamadoda, ngokwe-National Institute of Diabetes kunye neDigestive and Kidney Diseases.

Ukuzimela ngokuzenzekelayo kwe-hepatitis kunokukhokelela ekugqibeleni:

• ukutshatyalaliswa kwesibindi
• ukuqina kwesibindi
• umhlaza wesibindi
• ukusilela kwesibindi
• isidingo sokufakelwa kwesibindi

Kuya kufuneka usoloko uxoxa ngayo nayiphi na imibuzo onayo malunga neziphumo zakho zovavanyo kunye nomboneleli wakho wezempilo. Ukuba kukho imfuneko, baya kuba nakho ukumisela olona nyango lwakho lubalaseleyo.