Ukunyanga uxinzelelo lwegazi ngeCalcium Channel blockers

Umxholo

• Ngubani omele athathe i-calcium channel blocker?
• Isebenza njani i-calcium channel blocker
• Iindidi zecalcium channel blocker drug
• Zithini iziphumo ebezingalindelekanga kunye nomngcipheko?
• I-block block yecalcium yendalo

Yintoni iicalcium channel blockers?

Iicalcium channel blockers (CCBs) ludidi lwamayeza asetyenziselwa ukunyanga uxinzelelo lwegazi. Bakwabizwa ngokuba ngabachasi becalcium. Ziyasebenza njenge-ACE inhibitors ekunciphiseni uxinzelelo lwegazi.

Ngubani omele athathe i-calcium channel blocker?

Ugqirha wakho unokuyalela iiCCB ukuba:

• igazi elonyukayo
• ukubetha kwentliziyo okungaqhelekanga okubizwa ngokuba yi-arrhythmias
• iintlungu zesifuba ezinxulumene ne-angina

Uxinzelelo lwegazi oluphezulu lunokunyangwa ngezinye iindlela zonyango. Ugqirha wakho unokumisela zombini iCCB kunye nezinye iziyobisi ezixinzelelekileyo ngexesha elinye.

Izikhokelo ezitsha ezivela kwi-American College of Cardiology zincoma ukuba i-ACE inhibitors, i-diuretics, i-angiotensin-receptor blockers (ARBs), kunye neeCCB zibe ziyeza zokuqala zokuqwalasela xa uphatha uxinzelelo lwegazi oluphezulu. Amaqela athile abantu anokuxhamla ngakumbi kwiiCCB ngokudibeneyo namanye amayeza, kubandakanya:

• Abantu base-Afrika baseMelika
• abantu abanesifo sezintso
• abantu abadala
• abantu abanesifo seswekile

Isebenza njani i-calcium channel blocker

Ii-CCBs zinciphisa uxinzelelo lwegazi ngokunciphisa umda we-calcium okanye inqanaba apho i-calcium ingena kwinyama yemisipha kunye nakwiindonga zeseli zemithambo. I-calcium ivuselela intliziyo ukuba ivumelane ngamandla. Xa ukuhamba kwe-calcium kunqunyelwe, ukubetha kwentliziyo yakho akunamandla ngokubetha ngakunye, kwaye imithambo yegazi iyakwazi ukukhululeka. Oku kukhokelela ekunciphiseni uxinzelelo lwegazi.

Ii-CCBs ziyafumaneka kwinani leefomathi zomlomo, ukusukela kumacwecwe amafutshane okusombulula iipilisi ukuya kwiifomsile zokukhupha ezandisiweyo. Umthamo uya kuxhomekeka kwimpilo yakho yonke kunye nembali yezonyango. Ugqirha wakho uya kuthatha iminyaka yakho ukuba ayithathele ingqalelo ngaphambi kokumisela amayeza ehlisa uxinzelelo lwegazi. IiCCB zihlala zinamathuba amancinci okubangela iziphumo ebezingalindelekanga kubantu abangaphezulu kweminyaka engama-65.

Iindidi zecalcium channel blocker drug

Iiklasi ezintathu eziphambili zamachiza eCCB asekwe kubume bemichiza kunye nomsebenzi:

• Dihydropyridines. Oku kusebenza ikakhulu kwimithambo.
• IiBenzothiazepines. Oku kusebenza kwizihlunu zentliziyo kunye nemithambo.
• Iiphenylalkylamines. Oku kusebenza ikakhulu kwizihlunu zentliziyo.

Ngenxa yesenzo sabo, i-dihydropyridines zihlala zisetyenziselwa ukunyanga uxinzelelo lwegazi kunezinye iiklasi. Oku kungenxa yokukwazi kwabo ukunciphisa uxinzelelo lwe-arterial kunye ne-vascular resistance. I-Dihydropyridine calcium antagonists zihlala ziphela kwisimamva "-pine" kwaye zibandakanya:

• iamlodipine (iNorvasc)
• felodipine (Plendil)
• yiso
• iNicardipine (iCardene)
• I-nifedipine (iAdalat CC)
• nimodipine (Nymalize)
• nitrendipine

Ezinye ii-CCB eziqhelekileyo ezimiselweyo ukunyanga i-angina kunye nokubetha kwentliziyo okungaqhelekanga yi-verapamil (Verelan) kunye ne-diltiazem (iCardizem CD).

Zithini iziphumo ebezingalindelekanga kunye nomngcipheko?

IiCCBs zinokunxibelelana nezinye iziyobisi okanye izongezo ozithathayo. Qinisekisa ukuba ugqirha wakho unoluhlu oluhlaziyiweyo lwawo onke amayeza akho, iivithamini, kunye nezongezo zemifuno.

IiCCB kunye neemveliso zeediliya, kubandakanya iziqhamo kunye nejusi, akufuneki zithathwe kunye. Iimveliso zeediliya ziyaphazamisa ukukhutshwa kwesiyobisi ngendlela eqhelekileyo. Kunokuba yingozi ukuba izixa ezikhulu zeziyobisi ziqokelelana emzimbeni wakho. Linda ubuncinci iiyure ezine emva kokuba uthathe amayeza akho ngaphambi kokuba usele ijusi yegrapefruit okanye utye iidiliya.

Iziphumo ebezingalindelekanga zeCCBs zibandakanya:

• isiyezi
• intloko ebuhlungu
• ukuqhina
• isilungulela
• isicaphucaphu
• irhashalala okanye ukugungxula, bubomvu bomzimba ebusweni
• ukuvuvukala kwimida esezantsi
• ukudinwa

Ezinye iiCCBs zinokwehlisa amanqanaba eswekile yegazi kwabanye abantu. Tshela ugqirha wakho malunga naziphi na iziphumo ebezingalindelekanga ohlangabezana nazo. Banokuhlengahlengisa idosi yakho okanye bacebise ukuba utshintshele kwelinye iyeza ukuba iziphumo ebezingalindelekanga zihlala ixesha elide, zingonwabisi, okanye zisongela impilo yakho.

I-block block yecalcium yendalo

I-Magnesium ngumzekelo wesondlo esisebenza njengeCCB yendalo. Uphando lubonakalisile ukuba amanqanaba aphezulu e-magnesium athintela ukuhamba kwe-calcium. Kwizifundo zezilwanyana, ukuxhaswa kwe-magnesium kubonakala kusebenza kakhulu kulutsha olunefuthe eliphakamileyo loxinzelelo lwegazi, ngaphambi kokuba bavelise uxinzelelo lwegazi. Kwakubonakala ngathi iyacotha ukuqhubela phambili koxinzelelo lwegazi. Ukutya okunotye kwe-Magnesium kubandakanya:

• irayisi emdaka
• iiamangile
• amandongomane
• cashews
• i-oat bran
• Ingqolowa egutyiweyo
• isoya
• iimbotyi ezimnyama
• iibhanana
• ispinatshi
• iponyoponyo

Buza ugqirha wakho ukuba ukutya ukutya okuphezulu kwi-magnesium kuya kuchaphazela amandla e-CCB owathathayo.