Gcwalisa uvavanyo lwegazi

Umxholo

• Luyintoni uvavanyo lokuncedisa ngegazi?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwegazi lokuncedisa?
• Kwenzeka ntoni ngexesha lokuvavanywa kwegazi?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo lwegazi lokuncedisa?
• Zithetha ntoni iziphumo?
• Izalathiso

Luyintoni uvavanyo lokuncedisa ngegazi?

Uvavanyo lwegazi lokuncedisa ukulinganisa isixa okanye umsebenzi wokuncedisa iiproteni egazini. Ukuxhasa iiproteni ziyinxalenye yenkqubo yokuncedisa. Le nkqubo yenziwe liqela leeproteni ezisebenza kunye namajoni omzimba ukuchonga kunye nokulwa nezinto ezibangela izifo ezinjengeentsholongwane kunye neebhaktiriya.

Zilithoba iiprotheyini zokuncedisa. Babhalwe i-C1 nge-C9. Ukuzalisa iiprotheni kunokulinganiswa ngokukodwa okanye kunye. Iiproteni ze-C3 kunye ne-C4 zezona zivavanywa ngokuxhaphakileyo njengeeprotein. Uvavanyo lwe-CH50 (ngamanye amaxesha lubizwa ngokuba yi-CH100) lilinganisa inani kunye nomsebenzi wazo zonke iiprotein ezinkulu zokuncedisa.

Ukuba uvavanyo lubonisa ukuba amanqanaba akho eeproteyini aqhelekanga okanye iiprotheyini azisebenzi kunye nenkqubo yomzimba yokuzikhusela komzimba njengoko kufanelekile, inokuba luphawu lwesifo sokuzimela komzimba okanye enye ingxaki yezempilo.

Amanye amagama: gcwalisa i-antigen, imisebenzi yokuncoma C3, C4, CH50, CH100, C1 C1q, C2

Isetyenziselwa ntoni?

Uvavanyo lwegazi lokuncedisa luhlala lusetyenziselwa ukuxilonga okanye ukubeka esweni ukuphazamiseka komzimba okufana:

• I-Lupus, isifo esinganyangekiyo esichaphazela amalungu amaninzi omzimba, kubandakanya amalungu, imithambo yegazi, izintso kunye nengqondo
• I-rheumatoid arthritis, imeko ebangela iintlungu kunye nokudumba kwamalungu, ikakhulu ezandleni nasezinyaweni

Ingasetyenziselwa ukunceda ukuxilonga izifo ezithile zebhakteria, i-virus, okanye i-fungal.

Kutheni ndifuna uvavanyo lwegazi lokuncedisa?

Unokufuna uvavanyo lwegazi xa unempawu zokuphazamiseka komzimba, ngakumbi i-lupus. Iimpawu zelupus zibandakanya:

• Irhashalala elifana nebhabhathane empumlweni nasezidleleni zakho
• Ukudinwa
• Izilonda zomlomo
• Ukulahleka kweenwele
• Ubuntununtunu elangeni
• I-lymph nodes ezidumbileyo
• Intlungu yesifuba xa uphefumla ngokunzulu
• Intlungu edibeneyo
• Ifiva

Unokulufuna olu vavanyo ukuba unyangwa i-lupus okanye esinye isifo sokuzimela. Uvavanyo lunokubonisa ukuba unyango lusebenza kakuhle kangakanani.

Kwenzeka ntoni ngexesha lokuvavanywa kwegazi?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwegazi lokuncedisa.

Ngaba bukhona ubungozi kuvavanyo lwegazi lokuncedisa?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zakho zibonisa ezantsi kunexabiso eliqhelekileyo okanye umsebenzi owehlileyo weeproteni ezizalisayo, oko kunokuthetha ukuba unale miqathango ilandelayo:

• ILupus
• Irheumatoid Arthritis
• Isibindi
• Ezinye iintlobo zesifo sezintso
• I-angioedema yelifa, isifo esinqabileyo kodwa esibi kakhulu kumajoni omzimba. Ingabangela ukudumba kobuso kunye neendlela zomoya.
• Ukungondleki
• Usulelo oluphindaphindiweyo (ngesiqhelo ibacteria)

Ukuba iziphumo zakho zibonisa ngaphezulu kwexabiso eliqhelekileyo okanye ukwanda komsebenzi weeproteni ezizalisayo, kunokuthetha ukuba unale miqathango ilandelayo:

• Iindidi ezithile zomhlaza, ezinje ngeleukemia okanye i-non-Hodgkin lymphoma
• I-ulcerative colitis, imeko apho ulwelwesi lwamathumbu amakhulu kunye ne-rectum iya kudumba

Ukuba unyangwa i-lupus okanye esinye isifo se-autoimmune, ukwanda kwemali okanye umsebenzi wokuxhasa iiproteni kunokuthetha ukuba unyango lwakho luyasebenza.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Izalathiso

1. I-HSS: Isibhedlele soNyango olukhethekileyo [kwi-Intanethi]. ENew York: Isibhedlele soNyango olukhethekileyo; c2020. Ukuqonda iimvavanyo zaselebhu kunye neziphumo zeLupus (SLE); [ihlaziywe ngo-2019 ngoJulayi 18; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-4]. Ifumaneka kwi: https://www.hss.edu/conditions_understanding-laboratory-tests-and-results-for-systemic-lupus-erythematosus.asp
2. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. Ukudumba; [ihlaziywe ngo-2019 Oktobha 28; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/conditions/cirrhosis
3. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. Ukugqibezela; [ihlaziywe ngo-2019 Dec 21; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/tests/complement
4. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. ULupus; [ihlaziyiwe ngo-2020 Jan 10; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/conditions/lupus
5. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. Irheumatoid Arthritis; [ihlaziywe ngo-2019 Oktobha 30; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://labtestsonline.org/conditions/rheumatoid-arthritis
6. Isiseko seLupus saseMelika [kwi-Intanethi]. IWashington DC: iLupus Foundation yaseMelika; c2020. Iglosari yovavanyo lwegazi lwe-lupus; [icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.lupus.org/resource/glossary-of-lupus-blood-tests
7. Umanyano loPhando lweLupus [i-Intanethi]. ENew York: Umanyano loPhando lweLupus; c2020. Malunga neLupus; [icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/about-lupus
8. Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Uvavanyo lwegazi; [icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. Ukugcwalisa: Ubume; [ihlaziyiwe ngo-2020 Feb 28; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/complement
10. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. I-angioedema yelifa: Ubume; [ihlaziyiwe ngo-2020 Feb 28; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/hereditary-angioedema
11. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. Inkqubo ye lupus erythematosus: Ubume; [ihlaziyiwe ngo-2020 Feb 28; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/systemic-lupus-erythematosus
12. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. Isilonda sikabhobhosi: Isishwankathelo; [ihlaziyiwe ngo-2020 Feb 28; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/ulcerative-colitis
13. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2020. Health Encyclopedia: Clement C3 (Igazi); [icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=complement_c3_blood
14. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2020. Health Encyclopedia: Clement C4 (Igazi); [icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=complement_c4_blood
15. Ezempilo ze-UW [kwi-Intanethi]. Madison (WI): Izibhedlele zeYunivesithi yaseWisconsin kunye neGunya leKlinikhi; c2020. Ulwazi lwezeMpilo: Uvavanyo lokuGqibezela iLupus: Amagqabantshintshi ngesihloko; [ihlaziywe ngo-2019 kuMatshi 1; icatshulwe ngo-2020 Feb 28]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.uwhealth.org/health/topic/special/complement-test-for-lupus/hw119796.html

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.