I-CLA (i-Conjugated Linoleic Acid): Uhlolo olunzulu

Umxholo

• Yintoni i-CLA?
• Ifunyenwe Kwinyama Yenkomo Nobisi-Ngokukodwa Kwizilwanyana Ezityiswa Ingca
• Ngaba inokunceda ukutshiswa kwamafutha kunye nokulahleka kobunzima?
• IziBonelelo zezeMpilo ezinokubakho
• Iidosi ezinkulu zinokubangela iziphumo ebezingalindelekanga ezimandundu
• Isisombululo kunye noKhuseleko
• Umgca osezantsi

Ayingawo onke amafutha adalwe alinganayo.

Ezinye zazo zisetyenziselwa amandla, ngelixa ezinye zinempembelelo enamandla kwezempilo.

Iconjugated linoleic acid (CLA) yi-asidi enamafutha efumaneka kwinyama kunye nobisi ekukholelwa ukuba inezibonelelo ezahlukeneyo zempilo ().

Ikwayindlela eyaziwayo yokunciphisa ilahleko (2).

Eli nqaku livavanya ifuthe leCLA kubunzima bakho nakwimpilo yonke.

Yintoni i-CLA?

I-Linoleic acid yeyona omega-6 i-asidi ye-fatty exhaphakileyo, efumaneka kwisixa esikhulu kwioyile yemifuno kodwa nakokunye ukutya okwahlukeneyo ngexabiso elincinci.

Isimaphambili "esidibeneyo" sinento yokwenza nolungelelwaniso lweebhondi eziphindwe kabini kwimolekyuli eneasidi enamafutha.

Kukho iindlela ezingama-28 ezahlukeneyo zeCLA ().

Umahluko phakathi kwezi fomu kukuba iibhondi zazo eziphindwe kabini zicwangciswe ngeendlela ezahlukeneyo. Kubalulekile ukugcina engqondweni ukuba into efana ne-minuscule njengale inokwenza umahluko kwihlabathi kwiiseli zethu.

I-CLA iluhlobo lwe-polyunsaturated, omega-6 fatty acid. Ngamanye amagama, bubuchwephesha obunqamlezileyo-kodwa luhlobo lwendalo lwamafutha atshintshayo olwenzeka kukutya okunempilo okuninzi (4).

Izifundo ezininzi zibonisa ukuba amafutha atshintshisanayo oshishino-ahlukile kumafutha endalo afana ne-CLA-ayingozi xa esetyenziswa kwixabiso eliphezulu (,,).

I-CLA luhlobo lwe-omega-6 fatty acid. Ngelixa kubuchwephesha bethutyana obutshintshileyo, yahluke kakhulu kumanqatha ezithuthi ezihamba zonakalisa impilo yakho.

Ifunyenwe Kwinyama Yenkomo Nobisi-Ngokukodwa Kwizilwanyana Ezityiswa Ingca

Eyona mithombo iphambili yokutya kweCLA yinyama kunye nobisi lwezilwanyana ezityisayo, ezinjengeenkomo, iibhokhwe kunye neegusha.

Inani elipheleleyo le-CLA koku kutya kwahluka kakhulu kuxhomekeke kwinto etyiweyo zizilwanyana ().

Umzekelo, umxholo we-CLA ngama-300-500% aphezulu enkomeni nakubisi olusuka kwiinkomo ezitya ingca kuneenkomo ezityiswa iinkozo ().

Uninzi lwabantu sele lungenile kwi-CLA ngokutya kwabo. Umndilili wokutya e-US umalunga ne-151 mg ngosuku kwabasetyhini kunye ne-212 mg yamadoda ().

Gcina ukhumbula ukuba i-CLA oyifumana kwizongezo ayivelwanga kukutya kwendalo kodwa yenziwa kukutshintsha kwemichiza kwe-linoleic acid efumaneka kwioyile yemifuno ().

Ibhalansi yeefom ezahlukeneyo iphosakele kakhulu kwizongezo. Zineendidi zeCLA ezingazange zifunyanwe zininzi kwindalo (12, 13).

Ngesi sizathu, izongezo ze-CLA aziboneleli ngeziphumo ezifanayo zempilo njenge-CLA ekutyeni.

Eyona mithombo iphambili yokutya kwe-CLA lubisi kunye nenyama evela kwiinkomo, iibhokhwe kunye neegusha, ngelixa i-CLA isongezelelo senziwa ngokutshintsha kwemichiza ioyile yemifuno.

Ngaba inokunceda ukutshiswa kwamafutha kunye nokulahleka kobunzima?

Umsebenzi webhayoloji we-CLA wafunyanwa kuqala ngabaphandi abathi banokunceda ekulweni umhlaza kwiimpuku ().

Emva kwexesha, abanye abaphandi bagqibe kwelokuba kunokunciphisa amanqanaba omzimba ().

Njengoko ukutyeba kwanda kwihlabathi liphela, inzala ikhule kwi-CLA njengonyango olunokubakho lokwehla komzimba.

Ngapha koko, i-CLA inokuba yenye yezona zinto ziphononongiweyo ezijongwa ngokugqibeleleyo emhlabeni.

Izifundo zezilwanyana zicebisa ukuba i-CLA inokunciphisa amafutha emzimbeni ngeendlela ezininzi ().

Kwizifundo zeempuku, kwafunyanwa ukunciphisa ukutya, ukunyusa ukutshiswa kwamafutha, ukukhuthaza ukuphazamiseka kwamafutha kunye nokuthintela ukuveliswa kwamafutha (,,,).

I-CLA ikwafundwe kakhulu kwizilingo ezilawulwa ngokungahleliwe, imigangatho yegolide yovavanyo lwezesayensi ebantwini-nangona ibineziphumo ezixubeneyo.

Olunye uphononongo lubonisa ukuba i-CLA inokubangela ukulahleka kwamafutha ebantwini. Inokuphucula ukwakheka komzimba ngokunciphisa amafutha emzimbeni kunye nokwandisa ubunzima bemisipha (,,,,).

Nangona kunjalo, uninzi lwezifundo alubonisi siphumo (,,).

Kuphononongo lwezilingo ezili-18 ezilawulwayo, i-CLA yafunyanwa ukuba ibangele ilahleko ethobekileyo ().

Iziphumo zichazwa kakhulu kwiinyanga ezintandathu zokuqala, emva koko kulahleko lwamafutha ukuya kuthi ga kwiminyaka emibini.

Le grafu ibonisa ukuba ukunciphisa umzimba kunciphisa ixesha elingakanani:

Ngokweli phepha, i-CLA inokubangela ilahleko ye-avareji ye-0.2 yeekhilogram (01. kg) ngeveki kangangeenyanga ezintandathu.

Olunye uphononongo luqokelele ukuba i-CLA ibangele malunga ne-3 yeepawundi (i-1.3 kg) yokulahleka kwesisindo kune-placebo ().

Ngelixa ezi ziphumo zokulahleka kwesisindo zinokubaluleka ngokwezibalo, zincinci- kwaye zinokubakho iziphumo ebezingalindelekanga.

Nangona izongezo ze-CLA zinxulunyaniswa nelahleko yamafutha, iziphumo zincinci, azithembeki kwaye akunakulindeleka ukuba zenze umahluko kubomi bemihla ngemihla.

IziBonelelo zezeMpilo ezinokubakho

Kwindalo, i-CLA ifumaneka ikakhulu kwinyama enamafutha kunye nobisi lwezilwanyana ezirhubuluzayo.

Uninzi lwezifundo zokujonga ixesha elide ziye zavavanya umngcipheko wesifo kubantu abasebenzisa izixa ezikhulu zeCLA.

Ngokukodwa, abantu abafumana i-CLA eninzi kukutya basemngciphekweni ophantsi wezifo ezahlukeneyo, kubandakanya uhlobo lweswekile 2 kunye nomhlaza (,,).

Ukongeza, uphononongo kumazwe apho iinkomo zitya khona ingca ikakhulu endaweni yengqolowa- bonisa ukuba abantu abane-CLA emizimbeni yabo banomngcipheko ophantsi wesifo sentliziyo ().

Nangona kunjalo, lomngcipheko usezantsi ungabangelwa zezinye izinto zokukhusela kwiimveliso zezilwanyana ezityiswa ingca, ezinje nge-vitamin K2.

Ewe, inyama yenkomo kunye neemveliso zobisi ezisempilweni zisempilweni ngenxa yezinye izizathu.

Izifundo ezininzi zibonisa ukuba abantu abatya eyona CLA baphucule impilo ye-metabolic kunye nomngcipheko ophantsi wezifo ezininzi.

Iidosi ezinkulu zinokubangela iziphumo ebezingalindelekanga ezimandundu

Ubungqina bucebisa ukuba ukufumana ixabiso elincinci le-CLA yendalo ekutyeni kuyanceda.

Nangona kunjalo, i-CLA efumaneka kwizongezo yenziwa ngokuguqula ikhemikhali i-linoleic acid kwioyile yemifuno. Zihlala zikwimo eyahlukileyo kune-CLA efumaneka ngokwendalo ekutyeni.

Amanani ongezelelweyo nawo aphakame kakhulu kunezixa abantu abazifumana kubisi okanye inyama.

Njengoko kuhlala kunjalo, ezinye iimolekyuli kunye nezakha mzimba ziluncedo xa zifunyenwe kwixabiso lendalo kukutya okwenyani- kodwa iba yingozi xa ithathwa ngeedosi ezinkulu.

Izifundo zibonisa ukuba le yimeko ye-CLA.

Iidosi ezinkulu zokuncedisa i-CLA zinokubangela ukwanda kwamafutha esibindini sakho, nelilitye elijolise kwisifo se-metabolic syndrome kunye neswekile (,, 37).

Izifundo ezininzi kwizilwanyana nakubantu zityhila ukuba i-CLA inokuqhuba ukuvuvukala, ibangele ukunganyangeki kwe-insulin kunye ne-cholesterol elungileyo ye-HDL ",",.

Gcina ukhumbula ukuba uninzi lwezifundo ezifanelekileyo zezilwanyana zisebenzisa iidosi eziphakame kakhulu kunalezo zifunyanwa ngabantu.

Nangona kunjalo, ezinye izifundo zabantu ezisebenzisa iidosi ezifanelekileyo zibonisa ukuba izongezo zeCLA zinokubangela iziphumo ebezingalindelekanga ezininzi, kubandakanya urhudo, ukumelana ne-insulin kunye noxinzelelo lwe-oxidative ().

I-CLA efumaneka kwizincedisi ezininzi yahlukile kwi-CLA efumaneka ngokwendalo ekutyeni. Izifundo ezininzi zezilwanyana ziqwalasele iziphumo ebezingalindelekanga ezivela kwi-CLA, njengokunyuka kwamafutha esibindi.

Isisombululo kunye noKhuseleko

Uninzi lwezifundo kwi-CLA zisebenzise iidosi ze-3.2-6.4 iigram ngosuku.

Olunye uphononongo luqukumbele ukuba ubuncinci iigrama ezi-3 yonke imihla ziyimfuneko ukunciphisa umzimba ().

Iidosi ezifikelela kwi-6 yeegram ngosuku zithathwa njengezikhuselekileyo, kungekho ngxelo yeziphumo ebezingalindelekanga ezibi ebantwini (,).

I-FDA ivumela i-CLA ukuba yongezwe kukutya kwaye iyinike i-GRAS (ngokubanzi ithathwa njengekhuselekileyo) inqanaba.

Nangona kunjalo, khumbula ukuba umngcipheko weziphumo ebezingalindelekanga uyanda njengoko idosi inyuka.

Izifundo kwi-CLA ziye zasebenzisa imithamo ye-3.2-6.4 yeegram ngosuku. Ubungqina bucebisa ukuba abubangeli naziphi na iziphumo ezibi kakhulu kwiidosi ukuya kuthi ga kwi-6 iigram ngosuku, kodwa iidosi eziphezulu zonyusa umngcipheko.

Umgca osezantsi

Izifundo zibonisa ukuba i-CLA ineziphumo ezilinganiselweyo kuphela ekulahlekeni kobunzima.

Nangona kungabangeli naziphi na iziphumo ebezingalindelekanga ezibi kwiidosi ukuya kuthi ga kwi-6 gram ngemini, iinkxalabo zikhona malunga neziphumo zexesha elide ezempilo zamayeza awongezelelekileyo.

Ukuphulukana neeponti ezimbalwa zamafutha akunakulunga kwimingcipheko yezempilo enokubakho-ngakumbi njengoko kukho iindlela ezingcono zokulahlekelwa ngamanqatha.