Ngaba i-Ibuprofen ngokwenene yenza ukuba i-coronavirus ibe mandundu?

Umxholo

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Kucacile ngoku ukuba ipesenti enkulu yabemi iya kusulelwa yi-COVID-19. Kodwa oko akuthethi ukuba inani elifanayo labantu liya kuba neempawu ezisongela ubomi zenoveli coronavirus. Ke, njengoko ufunda ngakumbi malunga nendlela yokulungiselela usulelo olunokubakho lwe-coronavirus, unokuba ubambe umoya wesilumkiso saseFransi ngokuchasene nokusebenzisa uhlobo oluqhelekileyo lwe-painkiller kwiimpawu ze-coronavirus COVID-19-kwaye ngoku unemibuzo malunga nayo.

Ukuba uyiphosile, umphathiswa wezempilo e-France, u-Olivier Véran walumkisa malunga ne-NSAIDs ezinokubakho kwizifo ze-coronavirus kwi-tweet ngoMgqibelo. Ubhale wathi: "Ukuba unomkhuhlane, thatha i-paracetamol. Ukuba sele sele usebenzisa iziyobisi ezichasayo okanye ungathandabuzeki, cela ugqirha wakho ukuba akucebise."

Kwangoko ngala mini, iSebe lezeMpilo lase-France lakhupha ingxelo efanayo malunga namachiza e-anti-inflammatory kunye ne-COVID-19: amatyala e-COVID-19, "ifunda ingxelo. “Siyakukhumbuza ukuba unyango olucetyiswayo lwefiva enganyamezelekiyo kakuhle okanye iintlungu kumxholo we-COVID-19 okanye nayiphi na enye intsholongwane yokuphefumla yiparacetamol, ngaphandle kokugqithisa umthamo we-60 mg/kg/ngosuku kunye ne-3 g/ngosuku. kuvalwe umlomo." (Inxulumene: Yonke into ekufuneka uyazi malunga nokuHanjiswa kukaGqirha phakathi kweCoronavirus Pandemic)

Ukuhlaziya ngokukhawuleza: iziyobisi ezingekho-steroidal ezichasayo (i-NSAID) zinokunceda ukuthintela ukudumba, ukunciphisa iintlungu, kunye nefiva esezantsi. Imizekelo eqhelekileyo yee-NSAID ziquka i-aspirin (efumaneka kwi-Bayer kunye ne-Excedrin), i-naproxen sodium (efumaneka kwi-Aleve), kunye ne-ibuprofen (efumaneka kwi-Advil ne-Motrin). I-acetaminophen (ebizwa ngokuba yi-paracetamol eFransi) ikwakhulula iintlungu kunye nomkhuhlane, kodwa ngaphandle kokunciphisa ukuvutha. Mhlawumbi uyazi njengeTylenol. Zombini ii-NSAID kunye ne-acetaminophen inokuba yi-OTC okanye iyeza kuphela, kuxhomekeke kumandla abo.

Isizathu esisemva kwesi simo, esingabanjwanga nje ziingcali zempilo eFransi, kodwa nabanye abaphandi base-UK, kukuba ii-NSAID zinokuphazamisana nokusabela komzimba kwintsholongwane, ngokutsho. BMJ. Okwangoku, uninzi lwezazinzulu lubonakala ngathi luyakholelwa ukuba i-coronavirus ifumana ukungena kwiiseli nge-receptor ebizwa ngokuba yi-ACE2. Uphando ngezilwanyana lubonisa ukuba ii-NSAID zinokunyusa amanqanaba e-ACE2, kwaye ezinye izazinzulu zikholelwa ukuba ukunyuka kwamanqanaba e-ACE2 kuguqulela kwiimpawu ezinzima ze-COVID-19 xa sele wosulelekile.

Ezinye iingcali azikholelwa ukuba kukho ubungqina obaneleyo bezenzululwazi ukugunyazisa umyalelo waseFransi, nangona kunjalo. "Andicingi ukuba abantu kufuneka bazisuse kwii-NSAID," utshilo u-Edo Paz, MD, ugqirha wentliziyo kunye nosekela mongameli, kwezonyango e-K Health. "Isizathu sesi silumkiso sitsha kukuba ukudumba yinxalenye yempendulo yomzimba, kwaye ke iziyobisi eziyekisa impendulo yokuvuvukala, njengee-NSAID kunye ne-corticosteroids, zinokunciphisa ukuphendula komzimba okufuneka ukulwa i-COVID-19. Nangona kunjalo, ii-NSAID ziye ifundwe ngokubanzi kwaye akukho qhagamshelo lucacileyo kwiingxaki ezosulelayo. (Eyeleleneyo: Ezona mpawu ziqhelekileyo zeCoronavirus ekufuneka uzijonge, ngokweengcali)

U-Angela Rasmussen, Ph.D., ugqirha wezilwanyana kwiYunivesithi yaseColumbia, wamnika umbono wakhe kwikhonkco phakathi kwee-NSAID kunye ne-COVID-19 kumsonto we-Twitter. Uye wacebisa ukuba isincomo saseFransi sisekwe kwingqikelelo "exhomekeke kwiingqikelelo ezininzi ezinokuthi zingabi yinyani." Ubuye wathi akukho phando lubonisa ukuba ukonyuka kwamanqanaba e-ACE2 kukhokelela kwiiseli ezosulelekileyo; ukuba iiseli ezosulelekileyo zithetha ukuba intsholongwane iyakuveliswa; okanye ukuba iiseli ezivelisa intsholongwane zithetha iimpawu ezinzima kakhulu. (Ukuba unomdla wokufunda ngakumbi, uRasmussen wophula ngalinye lala manqaku mathathu ngokweenkcukacha kumsonto wakhe we-Twitter.)

“Ngokoluvo lwam, akunaxanduva ukuseka iingcebiso zekliniki kumagosa ezempilo kurhulumente kwi-hypothesis engangqinwanga ehambele phambili kwileta engakhange ijongwe ngoontanga,” ubhale watsho. "Ke musa ukuyilahla i-Advil yakho okanye uyeke ukuthatha amayeza oxinzelelo lwegazi okwangoku." (Eyeleleneyo: Yonke into ekufuneka uyazi malunga nokusasazeka kweCoronavirus)

Oko kuthethiweyo, ukuba ungathanda ukungazithathi ii-NSAID ngoku ngesizathu esinye okanye esinye, i-acetaminophen inokuphelisa iintlungu kunye nomkhuhlane, kwaye iingcali zithi kukho ezinye izizathu zokuba inokuba lukhetho olungcono kuwe.

Ingahambelani ne-COVID-19, ii-NSAID zidityaniswe nokusilela kwezintso, ukopha emathunjini, kunye neziganeko zentliziyo, "ucacisa uGqirha Paz. "Ke ukuba umntu ufuna ukunqanda la machiza, indawo yendalo iya kuba yi-acetaminophen, isithako esisebenzayo kwiTylenol. Oku kunokunceda ngeentlungu, iintlungu, kunye nomkhuhlane ohambelana ne-COVID-19 kunye nolunye usulelo."

Kodwa gcinani engqondweni: I-Acetaminophen ayinasiphako, nokuba. Ukuthatha isixa esigqithisileyo kunokubangela ukonakala kwesibindi.

Okukwintsusa: Xa ungathandabuzeki, xoxa ngezinto onokukhetha kuzo nomboneleli wakho wezempilo. Kwaye njengomgaqo oqhelekileyo wee-painkillers ezinjenge-NSAID kunye ne-acetaminophen, soloko unamathela kumthamo ocetyiswayo, nokuba uthatha i-OTC okanye inguqu yamandla kagqirha.

Ulwazi kweli bali luchanekile ngexesha lokushicilelwa. Njengoko uhlaziyo malunga ne-coronavirus i-COVID-19 iqhubeka nokuvela, kunokwenzeka ukuba ulwazi kunye neengcebiso kweli bali zitshintshile okoko kwapapashwa okokuqala. Siyakukhuthaza ukuba ujonge rhoqo ngezixhobo ezinjenge-CDC, i-WHO, kunye nesebe lezempilo likarhulumente kwindawo yakho yokufumana olona lwazi lwanamhlanje kunye neengcebiso.

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