Umbhali: Christy White
Umhla Wokudalwa: 6 Ucanzibe 2021
Hlaziya Umhla: 20 Eyenkanga 2024
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Umxholo

I-Estrone, ekwabizwa ngokuba yi-E1, yenye yeentlobo ezintathu zehomoni estrogen, ekwabandakanya i-estradiol, okanye i-E2, kunye ne-estriol, i-E3. Nangona i-estrone iluhlobo olukwisixa esincinci emzimbeni, yenye yezona zinto zinentshukumo enkulu emzimbeni kwaye, ke ngoko, uvavanyo lwayo lunokubaluleka ukuvavanya umngcipheko wezifo ezithile.

Umzekelo, kwabasetyhini emva kokuyeka ukuya exesheni, ukuba amanqanaba e-estrone aphezulu kune-estradiol okanye amanqanaba e-estriol, kunokubakho ukonyuka komngcipheko wentliziyo kunye nokuphuhlisa ezinye iintlobo zomhlaza.

Ke, olu vavanyo lunokuyalelwa ngugqirha xa kwenziwa ukutshintshwa kwehomoni ye-estrogen, ukuvavanya ibhalansi phakathi kwezinto ze-3, kuqinisekiswe ukuba akukho sifo sinikelweyo.

Yenzelwe ntoni

Olu vavanyo lunokunceda ugqirha ukuba achonge iingxaki esele zikhona okanye avavanye umngcipheko wokuba nesifo esihambelana namanqanaba e-estrone. Ngesi sizathu, olu vavanyo luyacelwa rhoqo, kubafazi, ukulungiselela:


  • Qinisekisa ukuxilongwa kokufikisa kwangethuba okanye ukulibaziseka;
  • Vavanya umngcipheko wokwaphuka kwabasetyhini emva kokuyeka ukuya exesheni;
  • Vavanya iidosi ngexesha lonyango lokutshintsha i-hormone;
  • Ukubeka iliso kunyango lwe-anti-estrogen kwimeko yomhlaza, umzekelo;
  • Vavanya ukusebenza kwee-ovari, kwimeko yokuncedisa ukuvelisa kwakhona.

Ukongeza, uvavanyo lwe-estrone lunokuyalelwa emadodeni ukuba avavanye iimpawu zobufazi njengokukhula kwebele, okwaziwa njenge-gynecomastia, okanye nokuqinisekisa isifo somhlaza ovelisa i-estrogen.

Luqhutywa njani uviwo

Uvavanyo lwe-estrone lwenziwa ngokuqokelelwa kwegazi ngokulula ngenaliti kunye nesirinji ngqo emthanjeni, ke kufuneka yenziwe esibhedlele okanye kwiiklinikhi zohlalutyo lweklinikhi.

Loluphi ulungiselelo oluyimfuneko

Akukho lungiselelo luthile lovavanyo lwe-estrone, nangona kunjalo, ukuba uthatha naluphi na uhlobo lonyango lokutshintsha i-hormone okanye izinto zokucwangcisa ngomlomo, ugqirha unokucela ukuba amayeza athathwe malunga neeyure ezi-2 ngaphambi kovavanyo, ukunciphisa umngcipheko obangela ubuxoki. utshintsho kumaxabiso.


Lithini ixabiso lesalathiso soviwo

Amaxabiso esalathiso kuvavanyo lwe-estrone ayahluka ngokobudala bomntu kunye nesini:

1. Kumakhwenkwe

Kwiminyaka ephakathiIxabiso lesalathiso
Iminyaka esi-70 ukuya kwi-16 pg / mL
Iminyaka eli-110 ukuya kwi-22 pg / mL
Iminyaka eli-1410 ukuya kwi-25 pg / mL
Iminyaka eli-1510 ukuya kwi-46 pg / mL
Iminyaka eli-18I-10 ukuya kwi-60 pg / mL

2. Kumantombazana

Kwiminyaka ephakathiIxabiso lesalathiso
Iminyaka esi-70 ukuya kwi-29 pg / mL
Iminyaka eli-10I-10 ukuya kwi-33 pg / mL
Iminyaka eli-12I-14 ukuya kwi-77 pg / mL
Iminyaka eli-14I-17 ukuya kwi-200 pg / mL

3. Abantu abadala

  • AmadodaI-10 ukuya kwi-60 pg / ml;
  • Abafazi ngaphambi kokuyeka ukuya exesheni: 17 ukuya ku-200 pg / mL
  • Abafazi emva kokuyeka ukuya exesheni: 7 ukuya kwi-40 pg / mL

Oko kuthethwa sisiphumo soviwo

Iziphumo zovavanyo lwe-estrone kufuneka zihlale zivavanywa ngugqirha owacelileyo, njengoko ukuxilongwa kwahluka kakhulu ngokobudala kunye nesini somntu ovavanyiweyo.


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