Uvavanyo lwe-PTH (parathormone): yintoni kunye nokuba iziphumo zithetha ntoni

Umxholo

• Luqhutywa njani uviwo
• Singathetha ntoni isiphumo

Uvavanyo lwe-PTH luyacelwa ukuze kuvavanywe ukusebenza kwamadlala e-parathyroid, ezincinanana ezincinci ezikwi-thyroid ezinomsebenzi wokuvelisa i-hormone ye-parathyroid (PTH). I-PTH iveliswa ukuthintela i-hypocalcemia, oko kukuthi, i-calcium esezantsi egazini, enokukhokelela ekubanjweni kunye nokusilela kwentliziyo kwiimeko ezinobuzaza kwaye xa kungekho lunyango. Funda ngakumbi malunga nokuba yintoni i-hypocalcemia kwaye yintoni enokubangela.

Olu vavanyo aludingi kuzila kwaye lwenziwa ngesampulu yegazi encinci. Idosi ye-PTH iyacelwa ikakhulu ukuba ichaze i-hypo okanye i-hyperparathyroidism, kodwa iyafuneka ekulandeleni abaguli abanesifo esinganyangekiyo sezintso, kwaye ihlala icelwa kunye nomthamo wecalcium egazini. Kubantu ngaphandle kotshintsho kwimveliso yehomoni yeparathyroid, amaxabiso aqhelekileyo egazini kufuneka phakathi kwe-12 kunye ne-65 pg / mL, zinokwahluka ngokwelabhoratri.

Nangona ulungiselelo lungeyomfuneko phambi koviwo, kubalulekile ukwazisa ugqirha malunga nokusetyenziswa kwawo nawaphi na amayeza, ngakumbi amayeza athomalalisayo, njengePropofol, umzekelo, njengoko zinokunciphisa uxinzelelo lwe-PTH, oko ke kuphazamise ukutolika kwesiphumo ngugqirha. Ukongeza, kuyacetyiswa ukuba ingqokelela yenziwe kwilabhoratri ethembekileyo okanye esibhedlele kunye neengcali eziqeqeshiweyo, kuba i-hemolysis, edla ngokubangelwa ziimpazamo kwingqokelela, inokuphazamisa iziphumo zovavanyo.

Luqhutywa njani uviwo

Uviwo aludingi kulungiswa, nangona kunjalo kuyacetyiswa ukuba ingqokelela yenziwe kusasa, njengoko uxinzelelo lwayo lunokwahluka yonke imihla. Igazi eliqokelelweyo lithunyelwa elebhu, apho liqhubekeka lize lifakwe kwisixhobo apho uhlalutyo lwenziwe khona. Iziphumo zihlala zikhutshwa malunga neeyure ezingama-24 emva kokuqokelelwa.

IHarathyroid hormone iveliswa ngokuphendula kugcino lwecalcium esezantsi. Isebenza emathanjeni, kwizintso nasemathunjini ukwenzela ukwandisa ukufumaneka kwecalcium egazini kunye nokuthintela i-hypocalcemia. Ukongeza, i-PTH inoxanduva lokunyusa ukufakwa kwe-vitamin D emathunjini.

Umsebenzi we-PTH ulawulwa yenye ihomoni, i-calcitonin, eqala ukuveliswa xa amanqanaba e-calcium ephezulu kakhulu, oko ke kunciphisa ukuveliswa kwe-PTH kunye nokukhuthaza ukuphuma kwe-calcium kumchamo, umzekelo. Qonda ukuba yenziwa njani kwaye yintoni uvavanyo lwecalcitonin.

Singathetha ntoni isiphumo

Iziphumo zovavanyo zitolikwa ngugqirha kunye nomthamo wecalcium, kuba ukuveliswa kweparathormone kuxhomekeke kuxinzelelo lwecalcium egazini.

• Ihomoni ephezulu yeparathyroid: Ihlala ibonisa inkqubela ye-hyperparathyroidism, ngakumbi ukuba inqanaba legazi le-calcium liphezulu. Ukongeza kwi-hyperparathyroidism, i-PTH inokuphakanyiswa kwimeko yokusilela okungapheliyo kwezintso, ukusilela kwe-vitamin D kunye ne-hypercalciuria. Qonda ukuba yintoni i-hyperparathyroidism kunye nendlela yokuyinyanga.
• Ihomoni ephantsi parathyroid: Ibonisa i-hypoparathyroidism, ngakumbi ukuba amanqanaba egazi e-calcium asezantsi. I-PTH ephantsi okanye engabonakaliyo inokubonisa isifo se-autoimmune, ukukhula okungalunganga kwamadlala okanye emva kweenkqubo zotyando. Jonga ukuba yintoni i-hypoparathyroidism kwaye uyichonga njani.

Uvavanyo lwe-PTH luyacelwa ngugqirha xa ikrokrela i-hypo okanye i-hyperparathyroidism, ngaphambi nasemva kokwenza iinkqubo zotyando ezibandakanya i-thyroid okanye xa kukho iimpawu zehypo okanye i-hypercalcemia, njengokudinwa kunye nentlungu esiswini, umzekelo. Fumanisa ukuba zeziphi izizathu eziphambili ze-calcium egazini kunye nendlela yokuyinyanga.