Unyango oluPhucukileyo nolwexesha elizayo lweParkinson's

Umxholo

• Ukukhuthaza Ubunzulu beBongo
• Unyango lweGene
• Unyango lwe-Neuroprotective Therapies
• Iimpawu zebhayoloji
• Ukutshintshwa kweNeural

Nangona kungekho nonyango yesifo sika-Parkinson, uphando olutshanje luye lwakhokelela ekuphuculeni unyango.

Inzululwazi kunye noogqirha basebenza kunye ukufumana unyango okanye indlela yokuthintela. Uphando lukwafuna ukuqonda ukuba ngubani onokuthi aphuhlise esi sifo. Ukongeza, oososayensi bafunda ngemfuza kunye nemeko yokusingqongileyo eyonyusa ithuba lokuchongwa.

Nazi iindlela zonyango lwamva nje lokuphazamiseka kwemithambo-luvo.

Ukukhuthaza Ubunzulu beBongo

Ngo-2002, i-FDA yavuma ukuvuselela ingqondo (DBS) njengonyango lwesifo sika-Parkinson. Kodwa inkqubela phambili kwi-DBS yayilinganiselwe kuba inye kuphela inkampani evunyiweyo yokwenza isixhobo esisetyenziselwa unyango.

NgoJuni 2015, i-FDA ivume. Esi sixhobo sinokufakwa sincede ukunciphisa iimpawu ngokuvelisa iimpompo zombane ezincinci emzimbeni wonke.

Unyango lweGene

Abaphandi abakayifumani indlela eqinisekileyo yokunyanga iParkinson, ukucothisa ukuqhubela phambili, okanye ukubuyisela umva kumonakalo wobuchopho obubangelwayo. Unyango lwe-Gene lunamandla okwenza zontathu ezi zinto. Abaliqela bafumanise ukuba unyango lwemfuza lunokuba yonyango olukhuselekileyo nolusebenzayo kwisifo sika-Parkinson.

Unyango lwe-Neuroprotective Therapies

Ngaphandle konyango lwemfuza, abaphandi bakwaphucula unyango lwe-neuroprotective. Olu hlobo lonyango lunokunceda ukunqanda ukuqhubela phambili kwesi sifo kunye nokuthintela iimpawu ukuba zingabi mandundu.

Iimpawu zebhayoloji

Oogqirha banezixhobo ezimbalwa zokuvavanya ukuqhubela phambili kwesifo sikaParkinson. Ukulinganisa, ngelixa kuluncedo, kujonga kuphela ukuqhubela phambili kweempawu zeemoto ezinxulumene nesifo sikaParkinson. Ezinye izikali zokuhlela zikhona, kodwa azisetyenziswanga ngokubanzi ngokwaneleyo ukuba zinconywe njengesikhokelo ngokubanzi.

Nangona kunjalo, indawo ethembekileyo yophando inokwenza ukuvavanya isifo sikaParkinson kube lula kwaye kuchane ngakumbi. Abaphandi banethemba lokufumanisa i-biomarker (iseli okanye ufuzo) oluya kukhokelela kunyango olusebenzayo.

Ukutshintshwa kweNeural

Ukulungisa iiseli zengqondo ezilahlekileyo kwisifo sikaParkinson yindawo ethembisayo yonyango lwexesha elizayo. Le nkqubo ithatha indawo yeeseli zengqondo ezigulayo neziswelekileyo ngeeseli ezintsha ezinokukhula zande. Kodwa uphando lokuhanjiswa kwe-neural lube neziphumo ezixubeneyo. Abanye abaguli baphucule ngonyango, ngelixa abanye bengakhange babone kuphucuka kwaye bade baba neengxaki ezininzi.

Kude kube kufunyenwe unyango lwesifo sikaParkinson, amayeza, unyango, kunye notshintsho kwindlela yokuphila zinokunceda abo bakule meko baphile ubomi obungcono.