Yintoni i-galactorrhea, izizathu eziphambili kunye nonyango

Umxholo

• Izizathu eziphambili
• Iimpawu eziqhelekileyo
• Indlela yokuchonga
• Unyango lwenziwa njani

IGalactorrhea yimfihlo engalunganga yolwelo oluqukethe ubisi olusuka ebeleni, olubonakala emadodeni okanye kwabasetyhini abangakhulelwanga okanye abangancancisi. Ngokwesiqhelo luphawu olubangelwa kukonyuka kweprolactin, ihomoni eveliswa kwingqondo enomsebenzi wayo kukwenza ubisi ngamabele, imeko ebizwa ngokuba yi-hyperprolactinemia.

Ezona zinto zibangela ukwanda kweprolactin kukukhulelwa kunye nokuncancisa, kwaye kukho izizathu ezininzi zokonyuka okungalunganga, kubandakanya ithumba lobuchopho, ukusetyenziswa kwamayeza, anje nge-neuroleptics kunye ne-anti-depressants, ukukhuthaza amabele okanye ezinye izifo ze-endocrine, ezinje ngehypothyroidism kunye isifo se-ovary polycystic.

Ke, ukunyanga i-hyperprolactinemia kunye ne-galactorrhea, kuyafuneka ukusombulula unobangela wayo, nokuba kukususa iyeza okanye ukunyanga isifo esibangela ukuveliswa kobisi ngamabele.

Izizathu eziphambili

Oonobangela abaphambili bokuveliswa kobisi ngamabele kukukhulelwa kunye nokuncancisa, nangona kunjalo, igalactorrhea yenzeka, ikakhulu ngenxa yeemeko ezinje:

• Indawo yokuhlala adenoma: sisisu esilumkileyo se-pituitary gland, esinoxanduva lokuvelisa iihomoni ezininzi, kubandakanya iprolactin. Uhlobo oluphambili yi-prolactinoma, edla ngokubangela ukwanda kwenqanaba leprolactin yegazi enkulu kune-200mcg / L;
• Olunye utshintsho kwi-pituitary gland: umhlaza, i-cyst, ukudumba, i-irradiation okanye ukubetha kwengqondo, umzekelo;
• Ukukhuthaza amabele okanye udonga lwesifuba: owona mzekelo uphambili wokukhuthaza kukuncanciswa kwamabele lusana, oluvula amabele ekhulisa kwaye luqinise ukuveliswa kwepractactin yobuchopho kwaye, ngenxa yoko, ukuveliswa kobisi;
• Izifo ezibangela ukuphazamiseka kwehomoni: ezinye zezona ziphambili yi-hypothyroidism, i-cirrhosis yesibindi, ukusilela okungapheliyo kwezintso, isifo se-Addison kunye ne-polycystic ovary syndrome;
• Umhlaza webele: inokubangela i-galactorrhea kwingono enye, ihlala inegazi;
• Ukusetyenziswa kwamayeza: 
  • I-Antipsychotic, enje ngeRisperidone, Chlorpromazine, Haloperidol okanye iMetoclopramide;
  • Opiates, ezinjengeMorphine, iTramadol okanye iCodeine;
  • Isinciphisi se-asidi esiswini, njengeRanitidine okanye iCimetidine;
  • Izidambisi-zintlungu, ezinje ngeAmitriptyline, Amoxapine okanye Fluoxetine;
  • Ezinye iziyobisi ezichasayo, ezifana neVerapamil, Reserpina kunye neMetildopa;
  • Ukusetyenziswa kwehomoni, njenge-estrogens, anti-androgens okanye HRT.

Ukulala noxinzelelo zezinye iimeko ezibangela ukwanda kwemveliso yeprolactin, nangona kunjalo, kunqabile ukuba zibangele utshintsho olwaneleyo ukubangela i-galactorrhea.

Iimpawu eziqhelekileyo

IGalactorrhea luphawu oluphambili lwe-hyperprolactinemia, okanye ukugqitha kweprolactin emzimbeni, kwaye inokubonakala ekuhleni, ibisi okanye ligazi ngombala, kwaye ivele kwelinye okanye omabini amabele.

Nangona kunjalo, ezinye iimpawu kunye neempawu zinokuvela, kuba ukwanda kwehomoni kunokubangela utshintsho kwiihomoni zesini, ezinje ngokuncitshiswa kwe-estrogen kunye ne testosterone, okanye, kananjalo, ukuba kukho izihlunu kwincindi yebhinqa. Iimpawu eziphambili zezi:

• Amenorrhea, nto leyo ukuphazamiseka ovulation kunye sexesheni kwabasetyhini;
• Ukungabi namandla ngokwesini kunye nokungasebenzi kakuhle kwamadoda;
• Ukungachumi kunye nokunciphisa umnqweno wesini;
• IOsteoporosis;
• Intloko ebuhlungu;
• Utshintsho olubonakalayo, njengokudinwa kunye nombono weendawo eziqaqambileyo.

Utshintsho lwehormonal lunokuba noxanduva lokungachumi kwinxalenye yamadoda okanye yabasetyhini.

Indlela yokuchonga

IGalactorrhea ibonwa kuvavanyo lweklinikhi yezonyango, enokuthi izenzekele okanye ivele emva kokubonisa ingono. IGalactorrhea iqinisekiswa nanini na xa kufakwa ubisi emadodeni, okanye xa kubonakala kwabasetyhini abangakhulelwanga okanye abancancisayo kwiinyanga ezi-6 ezidlulileyo.

Ukuchonga unobangela wegalactorrhea, ugqirha uya kuvavanya imbali yamayeza kunye nezinye iimpawu umntu anokuhlangabezana nazo. Ukongeza, ezinye iimvavanyo zinokwenziwa ukuphanda unobangela wegalactorrhea, njengokulinganisa kweprolactin egazini, ukulinganiswa kwexabiso le-TSH kunye ne-T4, ukuphanda ngomsebenzi we-thyroid, kwaye, ukuba kukho imfuneko, ingqondo ye-MRI ukuphanda ubukho bamathumba. okanye olunye utshintsho kwi-pituitary gland.

Unyango lwenziwa njani

Unyango lwe-galactorrhea lukhokelwa yi-endocrinologist, kwaye luyahluka ngokuhambelana nezizathu zesifo. Xa sisiphumo esisecaleni sonyango, kuya kufuneka uthethe nogqirha ukuvavanya ukubakho kokunqunyanyiswa okanye ukutshintshwa kweli yeza kwelinye.

Xa kubangelwa sisifo, kubalulekile ukuba inyangwe ngokufanelekileyo, ukuze kuzinziswe ukuphazamiseka kwehomoni, umzekelo, ukubuyisela iihomoni ze-thyroid kwi-hypothyroidism, okanye ukusetyenziswa kwe-corticosteroids ye-pituitary granulomas. Okanye, xa i-galactorrhea ibangelwa yithumba, ugqirha unokucebisa unyango ngokususwa kotyando okanye iinkqubo ezinje ngeradiotherapy.

Ukongeza, kukho iziyobisi ezinokunciphisa ukuveliswa kweprolactin kunye nokulawula i-galactorrhea, ngelixa unyango olwenziweyo lusenziwa, njengeCabergoline kunye neBromocriptine, ezingamachiza eklasini yabachasi be-dopaminergic.