Yazi ukuba kuthetha ukuthini i-hormone ye-ACTH ephezulu okanye ephantsi

Umxholo

• Utshintsho olunokwenzeka kwi-ACTH
• Phezulu ACTH
• ACTH esezantsi
• Iingcebiso zoviwo

Ihomoni ye-adrenocorticotropic, ekwabizwa ngokuba yi-corticotrophin kunye nesigama esithi ACTH, iveliswa yidlala yebhinqa kwaye isebenza ngokukodwa ukuvavanya iingxaki ezinxulumene namadlala endlala. Ke, umlinganiso we-ACTH uluncedo ekuchongeni iimeko ezinje nge-Cushing's syndrome, isifo sika-Addison, i-ectopic secretion syndrome, umhlaza wemiphunga kunye nomhlaza wedlala lengqula kunye nokusilela kwendlala ye-adrenal, umzekelo.

Uvavanyo lwe-ACTH luhlala lucelwa ngugqirha kunye nomlinganiso wecortisol ukuze ubudlelwane phakathi kwezi hormone zimbini kuvavanywe, kuba i-ACTH ivuselela imveliso ye-cortisol. Ixabiso eliqhelekileyo le-ACTH egazini ukuya kuthi ga kwi-46 pg / mL, enokwahluka ngokwelabhoratri olwenziwa kuyo uvavanyo kunye nexesha lokuqokelela, kuba amanqanaba ale hormone ahluka yonke imini, kwaye ingqokelela iyacetyiswa ngentsasa.

Ixabiso leemviwo ze-ACTH lihluka phakathi kwe-R $ 38 kunye ne-R $ 50.00 kuxhomekeke kwilabhoratri, nangona kunjalo, yenziwe ifumaneke yi-SUS.

Utshintsho olunokwenzeka kwi-ACTH

I-ACTH ifihliwe kancinci emini, ngamanqanaba aphezulu kwi-6 kunye ne-8 kusasa kunye namanqanaba asezantsi nge-9 pm kunye ne-10 pm. Ukuveliswa kwale hormone kunyuka ikakhulu kwiimeko zoxinzelelo, ezithi zikhuthaze ukukhutshwa kwecortisol, enoxanduva lokulawula uxinzelelo, uxinzelelo kunye nokudumba. Funda ngakumbi malunga necortisol kunye nokuba yenzelwe ntoni.

Utshintsho olunokwenzeka kwi-ACTH lunokuba:

Phezulu ACTH

• Isifo sikaCushing's, esinokukhokelela kwimveliso eyandayo ye-ACTH ngengqondo yebhinqa;
• Ukungabikho kakuhle kwe-adrenal;
• Isifo iAdrenogenital syndrome sinciphise imveliso yecortisol;
• Ukusetyenziswa kwee-amphetamines, i-insulin, i-levodopa, i-metoclopramide kunye ne-mifepristone.

Ukugxininiswa okuphezulu kakhulu kwe-ACTH egazini kunokunyusa ukwaphuka kweepids, kwandise uxinzelelo lweeasidi ezinamafutha kunye neglycerol egazini, kukhuthaze ukugcinwa kwe-insulin kunye nokwandisa imveliso yehomoni yokukhula, i-GH. Qonda ukuba yintoni i-GH kunye nokuba yenzelwe ntoni.

ACTH esezantsi

• Hypopituitarism;
• Ukungonelani kwendawo yengqondo ye-ACTH-yesibini adrenal;
• Ukusetyenziswa kwe-corticosteroids, i-estrogens, i-spironolactone, i-amphetamines, utywala, i-lithium, ukukhulelwa, isigaba sokujikeleza sexesheni, imisebenzi yomzimba.

Uvavanyo luyalelwa ngugqirha xa umntu eneempawu ezinxulumene nokwanda okanye ukwehla kwe-cortisol egazini. Iimpawu ezinokuthi zibonise i-cortisol ephezulu kukutyeba kakhulu, ulusu olucekeceke nolubuthathaka, amanqaku abomvu krwe esiswini, amabala, ukwanda kweenwele zomzimba kunye neempawu ezinokubonisa ukuba iphantsi kwecortisol bubuthathaka, ukudinwa, ukwehla kobunzima, ubumnyama besikhumba kunye nokuphelelwa ngumdla.

Iingcebiso zoviwo

Ukwenza uvavanyo, kuyacetyiswa ukuba umntu azile ukutya ubuncinci iiyure eziyi-8 okanye ngokweengcebiso zonyango kwaye ingqokelela yenziwe kusasa, ngokukhethekileyo iiyure ezi-2 emva kokuba umntu evukile.

Ukongeza, kubalulekile ukuba ungenzi mthambo womzimba ngosuku loviwo okanye usuku olungaphambili kunye nokunciphisa ukusetyenziswa kwee-carbohydrate ezifana nesonka, irayisi, iitapile kunye nepasta iiyure ezingama-48 phambi koviwo, njengoko le hormone isebenza ukulawulwa kweeproteni, iswekile kunye ne-lipid metabolism.