Inositol: Izibonelelo, Iziphumo ebezingalindelekanga kunye nedosi

Umxholo

• Yintoni i-Inositol?
• Ngamana unokuba neziBonelelo zeMpilo yeNgqondo
• Ukuphazamiseka kuPanic
• Uxinzelelo
• Ukuxhuzula
• Ngamana angaphucula iimpawu zePolycystic Ovary Syndrome
• Ngamana unokunceda uLawulo lweeMeko zoMngcipheko weSifo seMetabolic
• Ngamana unokuthintela isifo seswekile ngexesha lokukhulelwa
• Ezinye izibonelelo ezinokubakho
• Iziphumo ebezingalindelekanga kunye nonxibelelwano
• Imilinganiselo ekhuthaziweyo
• Umgca osezantsi

I-Inositol, ngamanye amaxesha ebizwa ngokuba yi-vitamin B8, ngokwendalo ivela ekutyeni okufana neziqhamo, iimbotyi, iinkozo kunye namandongomane ().

Umzimba wakho unokuvelisa i-inositol kwii-carbohydrate ozityayo.

Nangona kunjalo, uphando lubonisa ukuba i-inositol eyongezelelweyo ngohlobo lwezincedisi zinokuba nezibonelelo ezininzi zempilo.

Eli nqaku lijonga ngokubanzi izibonelelo, iidosi ezicetyiswayo kunye neziphumo ezinokubakho zezongezo ze-inositol.

Yintoni i-Inositol?

Nangona ihlala ibizwa ngokuba yi-vitamin B8, i-inositol ayisiyo vithamini konke konke kodwa iluhlobo lweswekile olunemisebenzi emininzi ebalulekileyo.

I-Inositol idlala indima ekwakhiweni komzimba wakho njengeyona nto iphambili kwiimbumba zeseli ().

Ikwachaphazela isenzo se-insulin, ihomoni eyimfuneko kulawulo lweswekile yegazi. Ukongeza, ichaphazela abathunywa bemichiza kwingqondo yakho, njenge-serotonin kunye ne-dopamine (,).

Kuqikelelwa ukuba ukutya okuqhelekileyo e-US kubandakanya i-1 gram ye-inositol ngosuku. Imithombo etyebileyo ibandakanya iinkozo, iimbotyi, amandongomane kunye neziqhamo kunye nemifuno ().

Nangona kunjalo, amathamo ongezelelweyo e-inositol ahlala ephezulu. Abaphandi bafundile izibonelelo zeedosi ukuya kuthi ga kwi-18 yeegram ngosuku-ngeziphumo ezithembisayo kunye neziphumo ebezingalindelekanga ezimbalwa.

Inositol luhlobo lweswekile olunceda ukubonelela ngolwakhiwo kwiiseli zakho. Ikwachaphazela i-hormone insulin kunye nomsebenzi wezithunywa zamachiza kwingqondo yakho.

Ngamana unokuba neziBonelelo zeMpilo yeNgqondo

Inositol inokunceda ukulungelelanisa iikhemikhali ezibalulekileyo kwingqondo yakho, kubandakanya nezo kukholelwa ukuba zichaphazela imeko yakho, njenge-serotonin kunye ne-dopamine ().

Into enomdla kukuba, abaphandi bafumanise ukuba abanye abantu abanexinzelelo, unxunguphalo kunye nokuphazamiseka okunyanzelekileyo banamanqanaba asezantsi e-inositol kwingqondo yabo (,).

Nangona uphando oluthe kratya luyafuneka, uphononongo oluninzi lubonisa ukuba i-inositol inokuba lolunye unyango kunyango lweemeko zempilo yengqondo. Kukwabonakala ngathi kuneziphumo ebezingalindelekanga ezimbalwa kunamayeza emveli ().

Ukuphazamiseka kuPanic

Ngelixa uphando lusasikelwe umda, izongezo ze-inositol zinokuba luncedo kunyango lokuphazamiseka, uhlobo olubi loxinzelelo.

Abo banengxaki yokuphazamiseka banamava okuhlaselwa rhoqo kukunkwantya, okuba ziimvakalelo ngesiquphe zoloyiko olukhulu. Iimpawu zibandakanya ukubetha kwentliziyo okukhawulezileyo, ukuphefumla kancinci, isiyezi, ukubila kunye nokugungqa okanye ukuziva ndindisholo ezandleni (7).

Kwisifundo esinye, abantu abangama-20 abanengxaki yokuphazamiseka bathathe isongezelelo se-18-gram inositol okanye amayeza aqhelekileyo oxinzelelo mihla le kwinyanga enye. Abo bathatha i-inositol babenesifo esothusayo esincinci ngeveki, xa kuthelekiswa nabantu abathatha amayeza oxinzelelo ().

Kwangokunjalo, kwisifundo seveki ezi-4, abantu abathile bafumana uhlaselo lophantsi oluncinci nangaphantsi xa bethatha i-12 gram ye-inositol ngosuku ().

Uxinzelelo

I-Inositol inokuphucula iimpawu zoxinzelelo, kodwa uphando lube neziphumo ezixubeneyo.

Umzekelo, uphononongo lwakwangoko lubonakalise ukuba ukuthatha i-12-gram inositol yongeze yonke imihla iiveki ezi-4 ziphucule iimpawu kubantu abanexinzelelo ().

Ngokwahlukileyo, izifundo ezalandelayo azikwazanga ukubonisa naziphi na izibonelelo ezibalulekileyo ().

Ngokubanzi, abukho ubungqina obaneleyo bokuchaza ukuba i-inositol inefuthe lokwenyani kuxinzelelo.

Ukuxhuzula

Njengakwezinye iimeko zempilo yengqondo, uphando ngeziphumo ze-inositol kunye nokuphazamiseka kwengqondo okulinganiselweyo. Nangona kunjalo, iziphumo zophando lokuqala zibonakala zithembisa (,).

Umzekelo, uphononongo oluncinci ebantwaneni abanengxaki yokuphazamiseka kwengqondo okuguquguqukayo lubonakalise ukunciphisa kweempawu zedemana kunye noxinzelelo xa indibaniselwano ye-3 gram ye-omega-3 fatty acids ukuya kuthi ga kwi-2 gramu ye-inositol yathathwa yonke imihla iiveki ezili-12 ().

Ukongeza, uphononongo lubonisa ukuba i-3-6 gram ye-inositol ethathwe yonke imihla inokunceda ukunciphisa iimpawu ze-psoriasis ezibangelwa yi-lithium, iyeza eliqhelekileyo elisetyenziselwa ukunyanga ukuphazamiseka kwengqondo (,).

Nangona uphando oluthe kratya luyafuneka, i-inositol ibonisa ukubanakho njengenye indlela yokhetho kunyango lweemeko zempilo yengqondo, kubandakanya ukungoyiki, uxinzelelo kunye nokuphazamiseka kwengqondo.

Ngamana angaphucula iimpawu zePolycystic Ovary Syndrome

I-Polycystic ovary syndrome (i-PCOS) yimeko ebangela ukungalingani kwamahomoni kwabasetyhini, oko kunokukhokelela kumaxesha angaqhelekanga kunye nokungachumi. Ukufumana ubunzima, iswekile ephezulu yegazi kunye ne-cholesterol engafunekiyo kunye namanqanaba e-triglyceride nawo anengxaki nge-PCOS (16).

Izongezo ze-Inositol zinokuphucula iimpawu ze-PCOS, ngakumbi xa zidityaniswe ne-folic acid.

Umzekelo, uphononongo lweklinikhi lubonisa ukuba idosi yemihla ngemihla ye-inositol kunye ne-folic acid inokunceda ukunciphisa amanqanaba e-triglycerides egazini. Banokuphucula ukusebenza kwe-insulin kunye noxinzelelo lwegazi olusezantsi kancinane kwabo bane-PCOS (,,).

Ngaphezulu, uphando lokuqala lufumanise ukuba indibaniselwano ye-inositol kunye ne-folic acid inokukhuthaza ukukhutshwa kwe-ovulation kubafazi abanemicimbi yokuzala evela kwi-PCOS (, 21).

Kwisifundo esinye, i-4 gram ye-inositol kunye ne-400 mcg ye-folic acid ethathwe yonke imihla iinyanga ezi-3 inyanzelisa i-ovulation kwi-62% yabasetyhini abaphathwayo ().

I-Inositol inokunceda ukunciphisa amanqanaba egazi le-triglyceride, ukuphucula ukusebenza kwe-insulin, uxinzelelo lwegazi olusezantsi kunye nokukhuthaza ukukhutshwa kwe-ovulation kwabasetyhini abane-polycystic ovary syndrome (PCOS).

Ngamana unokunceda uLawulo lweeMeko zoMngcipheko weSifo seMetabolic

Izifundo zonyango zibonisa ukuba izongezo ze-inositol zinokuba luncedo kwabo bane-metabolic syndrome (,).

I-Metabolic syndrome liqela leemeko eziphakamisa umngcipheko wesifo esinganyangekiyo, kubandakanya isifo sentliziyo kunye nohlobo lweswekile yesi-2.

Ngokukodwa, iimeko ezintlanu zinxulunyaniswa nesifo se-metabolic syndrome ():

• Amafutha amaninzi endaweni yesisu
• Amanqanaba aphezulu e-triglycerides egazini
• Umgangatho ophantsi "olungileyo" we-HDL cholesterol
• Igazi elonyukayo
• Iswekile yegazi ephezulu

Kwisifundo sonyango sonyaka wonke kwabasetyhini abangama-80 abane-metabolic syndrome, i-2 gram ye-inositol ithathwa kabini ngemini kuncitshiswe amanqanaba e-triglyceride yegazi nge-avareji ye-34% kunye ne-cholesterol iyonke ngama-22%. Ukuphuculwa koxinzelelo lwegazi kunye neswekile yegazi kwabonwa ().

Ngelishwa, iipesenti ezingama-20 zabafazi abathatha izongezo ze-inositol abasakwazi ukufikelela kwiimpawu zesifo se-metabolic ekupheleni kophononongo ().

I-Inositol inokunceda ekulawuleni umngcipheko we-metabolism ngokunceda ukunciphisa amanqanaba egazi le-triglyceride, uxinzelelo lwegazi kunye neswekile yegazi. Inokuphucula amanqanaba e-cholesterol.

Ngamana unokuthintela isifo seswekile ngexesha lokukhulelwa

Abanye abantu basetyhini bafumana iswekile ephezulu yegazi ngexesha lokukhulelwa. Le meko ibizwa ngokuba sisifo seswekile sokukhulelwa (GDM) kwaye inzima ukuya kuthi ga kwi-10% yokukhulelwa e-US minyaka le (25,).

Kwizifundo zezilwanyana, i-inositol inxulumene ngqo nomsebenzi we-insulin, ihomoni elawula amanqanaba eswekile yegazi (,).

Zimbalwa kuphela izifundo ezifumanekayo kwisongezelelo kunye ne-GDM ebantwini. Nangona kunjalo, abanye bacebisa ukuba indibaniselwano ye-4 gram ye-myo-inositol kunye ne-400 mcg ye-folic acid kunokuba luncedo ekuthinteleni i-GDM xa ithathwa yonke imihla ngexesha lokukhulelwa (,,).

Nangona kunjalo, uphando oluninzi luyafuneka, njengoko ezinye izifundo zingakhange zibonise iziphumo ezifanayo ().

I-Inositol inokunceda ukuthintela amanqanaba aphezulu eswekile yegazi ngexesha lokukhulelwa xa ithathwa ngokudityaniswa ne-folic acid, kodwa kufuneka izifundo ezingaphezulu ukuqinisekisa oku.

Ezinye izibonelelo ezinokubakho

I-Inositol ifundwe njengonyango olunokubakho kwimeko ezininzi.

Ngaphandle kwezo sele zikhankanyiwe, uphando lubonisa ukuba i-inositol inokuba luncedo kwezi meko zilandelayo:

• Ukuphefumla kwesifo: Kwiintsana ngaphambi kwexesha, i-inositol ibonakala iluncedo ekunyangeni imiba yokuphefumla kwimiphunga engaphuhliswanga ().
• Uhlobo lwe-2 yeswekile: Isifundo sokuqala sibonisa ukuba i-inositol kunye ne-folic acid ethathwa yonke imihla kangangeenyanga ezi-6 inokunceda ukulawulwa kweswekile yegazi kubantu abane-2 yeswekile ().
• Ukuphazamiseka okungafunekiyo (OCD): Isifundo esincinci sicebisa ukuba i-18 gram ye-inositol ethathwe yonke imihla iiveki ezi-6 inokunciphisa iimpawu ze-OCD ().

I-Inositol lukhetho olunokubakho kunyango lweentsana ezinaphambi kokuba umntu abe nesifo sokuphefumla. Inokunceda nasekulawuleni iswekile egazini kubantu abanesifo seswekile sesi-2 kwaye inokunciphisa iimpawu zokuphazamiseka okungafunekiyo.

Iziphumo ebezingalindelekanga kunye nonxibelelwano

Izongezo ze-Inositol zibonakala ngathi ziyanyamezeleka kubantu abaninzi.

Nangona kunjalo, iziphumo ebezingalindelekanga ezixeliweyo zixeliwe ngeedosi ze-12 yeegram ngosuku okanye ngaphezulu. Oku kubandakanya isicaphucaphu, irhasi, ubunzima bokulala, intloko ebuhlungu, isiyezi nokudinwa ().

Ukuya kuthi ga kwi-4 yeigram ye-inositol mihla le ithathwe ngabafazi abakhulelweyo kwizifundo ngaphandle kweziphumo ezibi, nangona uphando ngakumbi luyafuneka kuluntu (,).

Akukho zifundo zaneleyo zokuchonga ukhuseleko lwezongezo ngelixa uncancisa. Nangona kunjalo, ubisi lwebele lubonakala ngathi lutyebile ngokwendalo kwi-inositol ().

Ukongeza, akucaci nokuba izongezo ze-inositol zikhuselekile ekusebenziseni ixesha elide. Kwizifundo ezininzi, ii-inositol supplements zithathwa kuphela unyaka okanye ngaphantsi.

Njengalo naluphi na uncediso, thetha nogqirha wakho ngaphambi kokuba uthathe i-inositol.

Izongezo ze-Inositol zinxulunyaniswa nezimbalwa kwaye zineziphumo ezibi kuphela. Uphando oluthe kratya luyafuneka ukumisela ukhuseleko lwayo kwabasetyhini abakhulelweyo nabancancisayo kunye nokusetyenziswa kwexesha elide.

Imilinganiselo ekhuthaziweyo

Zimbini iindlela eziphambili ze-inositol ezisetyenziswa kwizongezo, ezizezi myo-inositol (MYO) kunye ne-D-chiro-inositol (DCI).

Nangona kungekho sivumelwano saseburhulumenteni kolona hlobo lusebenzayo kunye nomthamo, oku kulandelayo kubonakala kuyasebenza kwizifundo zophando:

• Kwimeko yezempilo yengqondo: I-12-18 gram ye-MYO kanye yonke imihla kwiiveki ezi-4-6 (,,,).
• Kwi-polycystic ovary syndrome: 1.2 iigram zeDCI kanye yonke imihla, okanye 2 iigram ze-MYO kunye ne-200 mcg ye-folic acid kabini imihla kangangeenyanga ezi-6 (,).
• Isifo se-metabolic syndrome: Iigram ezi-2 ze-MYO kabini yonke imihla unyaka omnye ().
• Ukulawulwa kweswekile yegazi kwisifo seswekile sokukhulelwa: 2 gram ye-MYO kunye ne-400 mcg ye-folic acid kabini imihla ngemihla ngexesha lokukhulelwa (,,).
• Ukulawulwa kweswekile egazini kuhlobo 2 lweswekile: I-1 gram yeDCI kunye ne-400 mcg folic acid kanye yonke imihla iinyanga ezi-6 ().

Ngelixa ezi dosi ze-inositol zibonakala ziluncedo lweemeko ezithile kwithuba elifutshane, kufuneka uphando oluninzi ukumisela ukuba zikhuselekile kwaye ziyasebenza na ixesha elide.

Akukho mvumelwano yaseburhulumenteni yethamo elicetyiswayo le-inositol. Isisombululo kunye nohlobo lwe-inositol supplement iyahluka ngokuxhomekeke kwimeko.

Umgca osezantsi

Uphando lubonisa ukuba i-inositol inokunceda abantu abanempilo yengqondo kunye neemeko ze-metabolic, ezinje ngokuphazamiseka kwengqondo, uxinzelelo, ukuphazamiseka kwengqondo, i-polycystic ovary syndrome, isifo se-metabolic syndrome kunye neswekile.

Kubonakala ngathi kukhuselekile kubantu abaninzi kwaye kubangela ubumnene kuphela ukuba ngaba kukho naziphi na iziphumo ebezingalindelekanga kwiidosi zemihla ngemihla ukuya kwi-18 yeegram.

Ngelixa ukutya kwakho kusenokwenzeka ukuba kunexabiso elincinci le-inositol, ukuthatha isongezelelo kunokuba luncedo kwabanye.

Soloko uxoxa ngokusetyenziswa kwezincedisi kunye nomboneleli wakho wezempilo kuqala.