Isibindi kunye neCholesterol: Into omele uyazi

Umxholo

• Amanqanaba asempilweni echolesterol emzimbeni
• Iingxaki zomsebenzi wesibindi
• Isifo sesibindi esinamafutha esinganxili
• Isibindi
• Iziyobisi
• Iziphumo ze-cholesterol ephezulu
• Nini ukubona ugqirha
• Uxilongo
• Unyango
• Yenza njalo
  
• Kuphephe
  
• Imbonakalo
• Uthintelo

Intshayelelo kunye nesishwankathelo

Amanqanaba e-cholesterol alinganisiweyo kubalulekile ekugcineni impilo esempilweni. Isibindi yinxalenye engaziwayo yomgudu lowo.

Isibindi lelona dlala likhulu emzimbeni, elikwindawo ephezulu yesisu. Yinkosi yomzimba yokuchithwa kweziyobisi kunye nezinye izinto zangaphandle. Igcina i-glycogen, esetyenziswa ngumzimba ukufumana amandla. Kukwabalulekile ekwenzeni amafutha, icarbohydrate, kunye neeproteni. Isibindi esisempilweni senza konke oku kungaqapheleki.

Umsebenzi obalulekileyo wesibindi kukuvelisa kunye nokucaca emzimbeni. Uninzi lwengqwalaselo egxile kwi-cholesterol ichaza ukubakho kwayo kweziphumo ezinobungozi empilweni. Kodwa i-cholesterol iyimfuneko ekudalweni kwehomoni, ivithamin D, kunye nee-enzymes eziyimfuneko ekwetyisweni.

Iinyanda ezibizwa ngokuba lipoproteins zithwala i-cholesterol emzimbeni wonke. Iindidi ezimbini ezibalulekileyo zii-lipoproteins ezixineneyo (HDL) kunye neepoprotein ezixineneyo (LDL). "Ephakamileyo" kwaye "ephantsi" ibhekisa kwinxalenye yeprotein kumanqatha kwinqwaba. Umzimba ufuna zombini ezi ntlobo kumgangatho olawulwayo.

Amanqanaba asempilweni echolesterol emzimbeni

Kubalulekile ukwazi amanqanaba e-HDL ("elungileyo" ye-cholesterol), i-LDL ("embi" ye-cholesterol), kunye ne-cholesterol iyonke emzimbeni wakho. Uqikelelo olubi lwe-cholesterol iyonke yi-HDL, kunye ne-LDL, kunye nesinye kwisihlanu soluhlobo lwesithathu lwamafutha abizwa ngokuba yi-triglyceride.

Kucetyiswa la manqanaba alandelayo:

Amanqanaba e-HDL ubuncinci ama-milligram angama-40 kwidesilitha nganye (mg / dL) yegazi. Nantoni na engaphantsi koko inyusa umngcipheko wesifo sentliziyo. Inqanaba ubuncinci be-60 mg / dL inceda ukunciphisa umngcipheko wesifo sentliziyo.

Iingxaki zomsebenzi wesibindi

Iingxaki zomsebenzi wesibindi zinokuthintela amandla omzimba okuvelisa okanye ukucacisa i-cholesterol. Zombini iimeko zingenza i-spike kwi-cholesterol kwaye ichaphazele impilo yomntu. Ezi meko zilandelayo zinokuchaphazela isibindi ngendlela ebangela amanqanaba e-cholesterol ukuba angaqhelekanga.

Isifo sesibindi esinamafutha esinganxili

Eyona ndlela iqhelekileyo yesifo sokungasebenzi kakuhle kwesifo sesibindi esinamafutha (NAFLD). Ichaphazela malunga nekota enye yabemi. Ihlala ibonakala phakathi kwabantu abatyebe kakhulu okanye abanesifo seswekile.

I-NAFLD inxulunyaniswa ne-dyslipidemia, amanqanaba angaqhelekanga echolesterol kunye nezinto ezifanayo egazini. I-NAFLD nayo inokubangela, isitenxo kwindlela umzimba ohambisa ngayo amanqatha.

I-NAFLD igubungela iimeko ezahlukeneyo. Ngaphakathi kwe-NAFLD yeyona steatohepatitis (NASH) imbi kakhulu. Ukuchongwa kwe-NASH kuhlala kukhokelela kwisifo sokuqina kwesibindi, ukusilela kwesibindi, kunye ne-hepatocellular carcinoma.

Isibindi

I-Cirrhosis inokubangela ukonakala kunye nokuthintela isibindi ekuqhubeni imisebenzi esisiseko ye-metabolic. Imeko yempendulo kukulimala kwexesha elide kwilungu. Ukulimala kunokubandakanya ukuvuvukala kwesifo esinjenge-hepatitis C. Emva kwe-hepatitis C, ukusetyenziswa gwenxa kotywala ixesha elide yeyona nto ixhaphakileyo e-cirrhosis e-United States.

Iziyobisi

Omnye unobangela obalulekileyo weengxaki zesibindi ngumonakalo ovela kwiziyobisi. Umsebenzi wesibindi kukuxuba iikhemikhali emzimbeni. Oko kuyenza ukuba ibe semngciphekweni wokonzakala ukusuka kugqirha, ekhawuntareni, okanye kwiziyobisi zokuzonwabisa.

Ukulimala okuqhelekileyo kwesibindi kunye neziyobisi ezinxulumene nale miqathango zibandakanya:

Hepatitis Acute

Iziyobisi ezinxulumene noko:

• acetaminophen
• iqeac
• isoniazid
• nevirapine
• ritonavir
• troglitazone

I-hepatitis engapheliyo

Iziyobisi ezinxulumene noko:

• dantrolene
• diclofenac
• imethyldopa
• minocycline
• initrofurantoin

Ipateni exutyiweyo okanye i-hepatitis

Iziyobisi ezinxulumene noko:

• I-ACE inhibitors
• amoxicillin-clavulanic acid
• chlorpromazine
• erythromycin
• sulindac

Unyango lwe-steatohepatitis

Iziyobisi ezinxulumene noko:

• amiodarone
• tamoxifen

Imicrovesicular steatosis

Iziyobisi ezinxulumene noko:

• I-NRTIs
• i-valproic acid

Isifo seVeno-occlusive

Iziyobisi ezinxulumene noko:

• busulfan
• cyclophosphamide

Emva kokuyeka iyeza, ukonakala kwesibindi akuqhelekanga kwaye kuhlala kuncipha. Kwiimeko ezinqabileyo, umonakalo unokuba nzima okanye isigxina.

Iziphumo ze-cholesterol ephezulu

Amanqanaba aphezulu e-LDL cholesterol enyusa umngcipheko wedipozithi ezinqanaweni ezisa igazi entliziyweni. Amanqanaba asezantsi kakhulu e-HDL cholesterol abonisa ukuba umzimba awunako ukucoca iipleyiti kunye nezinye iidipozithi ezinamanqatha ezivela emzimbeni. Zombini ezi meko zenza umngcipheko wesifo sentliziyo kunye nokuhlaselwa sisifo sentliziyo.

Nini ukubona ugqirha

Umonakalo wesibindi unokuqhubela phambili iinyanga okanye iminyaka ngaphandle kweempawu. Ngexesha lokuvela kweempawu, ukonakala kwesibindi kuhlala kuyinto enkulu. Ezinye iimpawu zigunyazisa utyelelo kugqirha. Oku kubandakanya:

• i-jaundice (ulusu olutyheli namehlo)
• ukudinwa
• ubuthathaka
• Ukuphelelwa ngumdla wokutya
• ukufumba kolwelo esiswini
• utyekelo lokutyumka ngokulula

Uxilongo

Ugqirha unokukwazi ukufumanisa iingxaki zesibindi ngokujonga iimpawu zakho kunye nokugcwalisa imbali yonyango. Unokufumana iimvavanyo zesibindi sakho. Olu vavanyo lubandakanya

Uvavanyo lwe-enzyme yesibindi: Ii-enzymes eziqhelekileyo ezikule phaneli zi-alanine transaminase, i-aspartate transaminase, i-alkaline phosphatase, kunye ne-gamma-glutamyl transpeptidase. Amanqanaba aphakamileyo ayo nayiphi na kwezi enzymes anokubonisa ukonakala.

Uvavanyo lweprotheni yesibindiAmanqanaba asezantsi eeproteni globulin kunye nealbumin inokubonisa ukulahleka kwesibindi. Iprothrombin yiprotein yesibindi efunekayo ekunqandeni. Uvavanyo oluqhelekileyo luthatha ukuba kuthatha ixesha elingakanani ukuba igazi lakho lijiye. Ixesha elincinci lokujiya linokuthetha ukungabikho kweprothrombin kunye nomonakalo wesibindi.

Uvavanyo lweBilirubin: Igazi lithutha ibilirubin iye esibindini nakwinyongo. Emva koko ikhutshiwe esitulweni. Igazi kumchamo okanye i-bilirubin egqithisileyo egazini inokubonisa ukonakala kwesibindi.

Iphaneli yeepoprotein enye: Iphaneli ivavanya i-cholesterol yegazi kunye ne-tryglycerides kunye. Igazi litsalwa emva kokuzila ukutya.

Unyango

Unyango lwezifo zesibindi zihlala ziqala ngokujongana nemeko esisiseko. Iimeko ezahlukeneyo zesibindi zifuna utshintsho oluthile lokutya, kodwa iAmerican Liver Foundation ineengcebiso ngokubanzi.

Yenza njalo

• Yitya ukutya okuziinkozo, iziqhamo, imifuno, inyama kunye neembotyi, ubisi kunye neoyile ngokomlinganiselo. Ukutya okune-fiber enezinto eziphambili.
• Hlala hydrated.

Kuphephe

• ukutya okunamafutha amaninzi, iswekile, kunye netyuwa
• i-shellfish eluhlaza okanye engadliwayo
• utywala

Unyango lwe-cholesterol ephezulu kubandakanya izikhokelo zokutya ezifana nezo zesifo sesibindi. Unyango lwe-cholesterol ephezulu kaninzi kubandakanya iklasi yeziyobisi ezibizwa ngokuba zii-statins. Abaphandi bajonge ukuba ingaba ii-statins zikhuselekile kubantu abanesifo sesibindi ukuba bazisebenzise.

"Ngokubanzi, ii-statins zikhuselekile kwizigulana ezinesifo sesibindi," utshilo uDavid Bernstein, MD, FACG, inkosi ye-hepatology e-Northwell Health, kunye nonjingalwazi wezamayeza e-Hofstra Northwell School of Medicine eHempstead, NY. "Izigulana ezinesifo sokubola kwesifo kufuneka zibekwe esweni kakhulu, kodwa ngokubanzi, zikhuselekile."

“Ngaba kukho umngcipheko? Ewe, kodwa ngumngcipheko omncinci kakhulu kwaye izigulana zijongwa kwiinyanga ezintathu ukuya kwezintandathu zokuqala, utshilo uBernstein.

Imbonakalo

Ungenelelo lonyango luthembisa ngakumbi ulawulo olusebenzayo lwecholesterol, kwanaphakathi kwabantu abanesifo sesibindi. Kodwa utshintsho kwindlela yokuphila kunye nolawulo lokutya luhlala lubalulekile kwaye lusebenza ngendlela efanelekileyo yokulawula i-cholesterol ngokubandakanyeka kwesibindi.

Uthintelo

Icebisa ngendlela yokulawula amanqanaba aphezulu e-cholesterol yegazi ngokutya kunye notshintsho kwindlela yokuphila:

U-Bernstein ucebisa ukuba ezi zikhokelo zokuphila ziingcebiso ezilungileyo kuye nabani na ozama ukugcina i-cholesterol, kubandakanya nabo banomceli mngeni wesifo sesibindi.