I-panhypopituitarism: yintoni, iimpawu kunye nendlela yokwenziwa kwonyango

Umxholo

• Iimpawu eziphambili
• Unyango lwenziwa njani
• Izizathu ezinokubangela

I-Panhypopituitarism sisifo esinqabileyo esihambelana nokuncipha okanye ukunqongophala kwemveliso yehomoni ezininzi ngenxa yotshintsho kwilungu lobudoda, eli lidlala elikwingqondo elinoxanduva lokulawula amanye amadlala emzimbeni kwaye, ngenxa yoko, ekhokelela ukuveliswa kwehomoni ebalulekileyo ekusebenzeni kakuhle komzimba.

Ukunqongophala kwamahomoni kungakhokelela ekubonakaleni kweempawu ezininzi, ezinje ngokuhla kobunzima, utshintsho kumjikelo wokuya exesheni, ukunciphisa ukuphakama, ukudinwa okugqithisileyo kunye neengxaki zokuzala, umzekelo. Ke, eyona ndlela iphambili yokunciphisa iimpawu ze-panhypopituitarism kukutshintsha kwehomoni, ekufuneka yenziwe ngokwesikhokelo se-endocrinologist.

Iimpawu eziphambili

Iimpawu zepanhipopituitarismo zixhomekeke ekubeni zeziphi iihomoni ezingakhiqiswanga okanye ziveliswe kuxinzelelo oluncinci, umzekelo:

• Ukwehla kwesisindo ngenxa yokuhla kwehomoni yedlala lengqula;
• Ukuphelelwa ngumdla wokutya;
• Ukudinwa kakhulu;
• Imood iyatshintsha;
• Ubunzima bokukhulelwa kunye nokudodobala komjikelo wokuya exesheni, ngenxa yokuncipha kwemveliso yehomoni yesini sabasetyhini;
• Ukwehla kwamandla emveliso yobisi kwabasetyhini;
• Ukuncipha kwenqanaba kunye nokulibaziseka ukufikisa ebantwaneni, njengoko ukuveliswa kwehomoni yokukhula (GH) kusengozini;
• Ukuphulukana neendevu kunye neengxaki ezinxulumene nokuzala emadodeni, ngenxa yokuncipha kwemveliso ye testosterone kwaye, ngenxa yoko, ukukhula kwesidoda.

Ukusuka kwiimpawu ezichazwe ngumntu kunye novavanyo lwelabhoratri olujolise ekulinganiseni iihomoni ezisegazini, ugqirha we-endocrinologist uyakwazi ukugqibezela ukuxilongwa kwaye abonise ukuba ngawaphi amayeza umntu afanele ukuwathatha.

Abantu abane-panhypopituitarism kunokwenzeka ukuba baphuhlise i-insipidus yeswekile, eyenzeka ngenxa yokuncipha kwemveliso ye-antidiuretic hormone (ADH), ekhokelela ekwandeni koxinaniso lweglucose yegazi ngenxa yokwehla koxinaniso lwamanzi, ukongeza ukuphelelwa ngamanzi emzimbeni kunye nokunxanwa kakhulu. Funda ngakumbi ngesifo seswekile i-insipidus.

Unyango lwenziwa njani

Unyango lwenziwa ngokwesikhokelo se-endocrinologist kwaye lwenziwa ngokutshintsha kwehomoni ngokusebenzisa amayeza. Njengoko i-pituitary gland ilawula ukuveliswa kwehomoni ezininzi, kunokuba yimfuneko ukuba umntu atshintshe:

• I-ACTH, ekwabizwa ngokuba yi-adrenocorticotrophic hormone okanye i-corticotrophin, eveliswa yidlala yebhinqa kwaye ivuselele imveliso ye-cortisol, eyihomoni inoxanduva lokulawula impendulo yoxinzelelo kunye nokuvumela ukwakheka komzimba komzimba kwiimeko ezintsha. Qonda ukuba yeyantoni icortisol;
• TSH, ekwabizwa ngokuba yihomoni ekhuthaza idlala lengqula, eveliswa yidlala yebhinqa kwaye linoxanduva lokukhuthaza idlala lengqula ukuvelisa iihomoni T3 kunye ne-T4, edlala indima ephambili kwimetabolism;
• LH, Eyaziwa njenge-luteinizing hormone, ekhuthaza ukuveliswa kwe testosterone emadodeni kunye neprogesterone kwabasetyhini, kwaye FSH, Eyaziwa njenge-follicle evuselela i-hormone, evumela ukulawulwa kwemveliso yesidoda kunye nokuvuthwa kweqanda. Ke, xa kukho ukuhla kwimveliso yala mahomoni ngenxa yeengxaki kwi-pituitary gland, umzekelo, kuncipha ekuchumeni kwamadoda nabasetyhini ukongeza kwilahleko yeenwele kunye nokucinywa komjikelo wokuya exesheni, umzekelo. Funda ngakumbi ngehomoni FSH;
• GH, eyaziwa ngokuba yi-hormone yokukhula okanye i-somatotropin, iveliswa yi-pituitary gland kwaye inoxanduva lokukhula kwabantwana nakwishumi elivisayo, ukongeza ekuncedeni kwimisebenzi yokutya komzimba.

Ukongeza, ngenxa yotshintsho kwiimvakalelo ngenxa yotshintsho lwehomoni, ugqirha unokucebisa ngokusetyenziswa kwe-anti-depressants kunye ne-anxiolytics ukunciphisa iimpawu ezinxulumene nokutshintsha kweemeko ngesiquphe.

Ugqirha unokucebisa ngokutshintshwa kwe-calcium kunye ne-potassium, ezibalulekile iiminerali kwiinkqubo ezahlukeneyo ze-metabolic emzimbeni, kuba utshintsho oluthile lwehomoni lukhokelela ekwehleni koxinano lwezi minerali egazini.

Izizathu ezinokubangela

Esona sizathu sixhaphakileyo se-panhypopituitarism sisifo se-pituitary gland, esiya kuthi, ngokuxhomekeke kwinqanaba le-tumor, sinokufuna ukususwa kwe-pituitary gland. Nangona kunjalo, akusoloko kukho ithumba kwi-pituitary gland elithetha ukuba umntu uya kuva ubunzima yi-panhypopituitarism, eyenzeka kuphela xa kufuneka le ndlala isuswe.

Ukongeza, i-panhypopituitarism inokwenzeka ngenxa yosulelo oluchaphazela ingqondo, njenge-meningitis, umzekelo, isifo se-Simmonds, esisifo sokuzalwa, okanye nokuba sisiphumo semitha.