I-Polycystic Ovary Syndrome (i-PCOS): Iimpawu, oonobangela, kunye nonyango

Umxholo

• Yintoni i-PCOS?
• Ibangelwa yintoni?
• Imfuza
• Ukuxhathisa kwe-insulin
• Ukudumba
• Iimpawu eziqhelekileyo zePCOS
• I-PCOS ichaphazela njani umzimba wakho
• Ukungachumi
• Isifo seMetabolic syndrome
• Ukulala ngokuphefumla
• Umhlaza we-Endometrial
• Uxinzelelo
• Ichongwa njani iPCOS
• Ukukhulelwa kunye nePCOS
• Ukutya kunye neengcebiso ngendlela yokuphila ukunyanga iPCOS
• Unyango oluqhelekileyo
• Ukulawula inzala
• IMetformin
• Clomiphene
• Amayeza okususa iinwele
• Ugqirha
• Nini ukubona ugqirha
• Umgca wezantsi

Intshayelelo

I-Polycystic ovary syndrome (i-PCOS) yimeko echaphazela amanqanaba ehomoni yabasetyhini.

Abasetyhini abane-PCOS bavelisa ixabiso elingaphezulu kwesiqhelo kunamahomoni angamadoda. Ukungalingani kwamahomoni kubangela ukuba bangakwazi ukuya exesheni kwaye kubenza nzima ukuba bakhulelwe.

I-PCOS ikwabangela ukukhula kweenwele ebusweni nasemzimbeni, kunye nenkqayi. Kwaye kunokuba negalelo kwiingxaki zempilo zexesha elide ezinje ngesifo seswekile kunye nesifo sentliziyo.

Iipilisi zolawulo lokuzalwa kunye neziyobisi zeswekile zinokunceda ukulungisa ukungalingani kwehomoni kunye nokuphucula iimpawu.

Funda ukuze ujonge oonobangela be-PCOS kunye neziphumo zayo emzimbeni womfazi.

Yintoni i-PCOS?

I-PCOS yingxaki ngamahomoni achaphazela abasetyhini ngexesha lokuzala kwabo (iminyaka eli-15 ukuya kwengama-44). Phakathi kwe-2.2 kunye ne-26.7 yeepesenti yabasetyhini kweli qela leminyaka bane-PCOS (1,).

Abasetyhini abaninzi bane-PCOS kodwa abayazi. Kwisifundo esinye, ukuya kuthi ga kwiipesenti ezingama-70 zabasetyhini abane-PCOS abangafumaniswanga ().

I-PCOS ichaphazela amaqanda esetyhini, amalungu okuzala avelisa i-estrogen kunye neprogesterone - iihormoni ezilawula umjikelo wokuya exesheni. Ii-ovari zivelisa inani elincinci lamahomoni angamadoda abizwa ngokuba yi-androgens.

Ama-ovari akhulula amaqanda ukuba achunyiswe sisidoda sendoda. Ukukhutshwa kweqanda inyanga nenyanga kubizwa ngokuba yi-ovulation.

I-follicle-evuselela i-hormone (FSH) kunye ne-luteinizing hormone (LH) yokulawula i-ovulation. I-FSH ivuselela i-ovary ukuba ivelise i-follicle- ingxowa equlathe iqanda- emva koko i-LH ibangela ukuba i-ovary ikhuphe iqanda eliqolileyo.

I-PCOS yi "syndrome," okanye iqela leempawu ezichaphazela ama-ovari kunye ne-ovulation. Iimpawu zayo ezintathu eziphambili zezi:

• ama-cysts kwii-ovari
• amanqanaba aphezulu ehomoni yamadoda
• amaxesha angaqhelekanga okanye atsiweyo

Kwi-PCOS, iisaka ezininzi ezincinci ezigcwele ulwelo zikhula ngaphakathi kwii-ovari. Igama elithi "polycystic" lithetha "ii-cysts ezininzi."

Ezi ngxowa zezona zilwanyana, nganye ineliqanda elingavuthwanga. Amaqanda awaze akhule ngokwaneleyo ukuze aqalise i-ovulation.

Ukusilela kwamanqanaba okutshintsha kwe-ovulation e-estrogen, progesterone, FSH, kunye ne-LH. Amanqanaba e-Estrogen kunye neprogesterone asezantsi kunesiqhelo, ngelixa amanqanaba e-androgen aphezulu kunesiqhelo.

Amahomoni angamadoda ongezelelweyo aphazamisa umjikelo wokuya exesheni, ngenxa yoko abasetyhini abane-PCOS bafumana amaxesha ambalwa kunesiqhelo.

I-PCOS ayisiyonto intsha. Ugqirha wase-Italiya u-Antonio Vallisneri uqale wachaza iimpawu zakhe ngo-1721 ().

I-Polycystic ovary syndrome (i-PCOS) ichaphazela ukuya kuthi ga kwiipesenti ezingama-27 zabasetyhini ngexesha lokuzala kwabo (4). Ibandakanya ii-cysts kwii-ovari, amanqanaba aphezulu ehomoni yamadoda, kunye namaxesha angaqhelekanga.

Ibangelwa yintoni?

Oogqirha abazi ngqo ukuba yintoni ebangela iPCOS. Bakholelwa ukuba amanqanaba aphezulu ehomoni yamadoda athintela ama-ovari ekuveliseni iihomoni kunye nokwenza amaqanda ngesiqhelo.

Imfuza, ukumelana ne-insulin, kunye nokudumba konke kunxulunyaniswe nemveliso engaphezulu kwe-androgen.

Imfuza

Izifundo zibonisa ukuba i-PCOS isebenza kwiintsapho (5).

Kusenokwenzeka ukuba uninzi lwemfuza-hayi inye kuphela - enegalelo kwimeko (6).

Ukuxhathisa kwe-insulin

Ukufikelela kuma-70 ekhulwini kwabasetyhini abane-PCOS banokuxhathisa kwe-insulin, oku kuthetha ukuba iiseli zabo azikwazi ukusebenzisa i-insulin ngokufanelekileyo ().

I-insulini yincindi yedlala ekuthiwa yipancreas ukunceda umzimba usebenzise iswekile ekutyeni ukuze ufumane amandla.

Xa iiseli zingakwazi ukusebenzisa i-insulin ngokufanelekileyo, ibango lomzimba le-insulin liyanda. Ipancreas yenza i-insulin engaphezulu ukubuyekeza. I-insulin eyongezelelweyo ibangela ii-ovari ukuba zivelise iihomoni ezingamadoda.

Ukutyeba kakhulu ngoyena nobangela uphambili wokuxhathisa kwe-insulin. Zombini ukutyeba kunye nokunganyangeki kwe-insulin kunokunyusa umngcipheko kuhlobo 2 lweswekile (8).

Ukudumba

Abasetyhini abane-PCOS bahlala benamazinga okwanda kokudumba emzimbeni wabo. Ukutyeba kakhulu kunokuba negalelo kukudumba. Izifundo zidibanise ukuvuvukala okugqithileyo kumanqanaba aphezulu e-androgen ().

Oogqirha abazi ngqo ukuba yintoni ebangela iPCOS. Bakholelwa ukuba isuka kwizinto ezinje ngemfuza, ukumelana ne-insulin, kunye namanqanaba aphezulu okuvuvukala emzimbeni.

Iimpawu eziqhelekileyo zePCOS

Abanye abantu basetyhini baqala ukubona iimpawu ngexesha labo lokuqala. Abanye bafumanisa ukuba bane-PCOS emva kokuba befumene ubunzima obukhulu okanye babenengxaki yokukhulelwa.

Ezona mpawu zixhaphakileyo zePCOS zezi:

• Amaxesha angaqhelekanga. Ukunqongophala kwe-ovulation kuthintela ulusu lwesibeleko ekuchitheni inyanga nenyanga. Abanye abantu basetyhini abane-PCOS bafumana amaxesha angaphantsi kwesibhozo ngonyaka ().
• Ukopha kakhulu. Ukufakwa kwesibeleko kuyakha ixesha elide, ke amaxesha owafumanayo anokuba nzima kunesiqhelo.
• Ukukhula kweenwele. Ngaphezulu kweepesenti ezingama-70 yabasetyhini abanayo le meko bekhula iinwele ebusweni nasemzimbeni-kubandakanya nasemqolo, esiswini nasesifubeni (11). Ukukhula okungaphezulu kweenwele kuthiwa yi-hirsutism.
• Amabala. Amahomoni angamadoda angenza ulusu lube ne-oilier kunesiqhelo kwaye lubangele ukuqhekeka kwiindawo ezinje ngobuso, isifuba kunye nomqolo ongaphezulu.
• Ukutyeba kwakho. Ukufikelela kuma-80 ekhulwini kwabasetyhini abane-PCOS baninzi kakhulu okanye baninzi (11).
• Impandla yomntu. Izinwele esikhumbeni ziye zinciphe zize ziwe.
• Ubumnyama besikhumba. Amabala amnyama esikhumba anokwenza kwimizimba efana naleyo isentanyeni, kwi-groin naphantsi kwamabele.
• · Intloko ebuhlungu. Utshintsho lweHormone lunokubangela iintloko kubafazi abathile.

I-PCOS inokuphazamisa umjikelo wokuya esikhathini, ekhokelela kumaxesha ambalwa. Amabala, ukukhula kweenwele, ukutyeba, kunye namabala amnyama esikhumba zezinye zeempawu zemeko.

I-PCOS ichaphazela njani umzimba wakho

Ukuba namanqanaba e-androgen aphezulu kunesiqhelo anokuchaphazela ukuzala kwakho kunye neminye imiba yempilo yakho.

Ukungachumi

Ukukhulelwa, kuya kufuneka uphume. Abasetyhini abangayondli rhoqo rhoqo abayikhuphi amaqanda amaninzi ukuze achunyiswe. I-PCOS sesinye sezizathu eziphambili zokungachumi kwabasetyhini (12).

Isifo seMetabolic syndrome

Ukuya kuthi ga kwiipesenti ezingama-80 zabasetyhini abane-PCOS batyebe kakhulu okanye batyebe kakhulu (). Zombini ukutyeba kunye ne-PCOS zonyusa umngcipheko weswekile ephezulu yegazi, uxinzelelo lwegazi oluphezulu, i-HDL ("elungileyo") esezantsi ye-cholesterol, kunye ne-cholesterol ephezulu ye-LDL ("embi").

Ngokudibeneyo, ezi zinto zibizwa ngokuba yi-metabolic syndrome, kwaye zonyusa umngcipheko wesifo sentliziyo, isifo seswekile kunye nokubetha.

Ukulala ngokuphefumla

Le meko ibangela ukunqumama okuphindaphindiweyo ekuphefumleni ebusuku, okuphazamisa ukulala.

I-apnea yokulala ixhaphake kakhulu kubafazi abatyebe ngakumbi-ngakumbi ukuba bane-PCOS. Umngcipheko wokuphefumla ubuthongo ngamaxesha ama-5 ukuya kwali-10 aphezulu kwabasetyhini abatyebe kakhulu abane-PCOS kunalawo angenayo i-PCOS (14).

Umhlaza we-Endometrial

Ngexesha le-ovulation, i-uterine lining sheds. Ukuba awuyikhupha i-ovulation inyanga nenyanga, i-lining ingakha.

Umbane oxineneyo wesibeleko unokunyusa umngcipheko womhlaza we-endometrium (15).

Uxinzelelo

Zombini utshintsho lwehomoni kunye neempawu ezinje ngokukhula kweenwele okungafunekiyo zinokuchaphazela kakubi iimvakalelo zakho. Uninzi lwe-PCOS luphela luba noxinzelelo kunye noxinzelelo (16).

Ukungalingani kweHormone kunokuchaphazela impilo yomfazi ngeendlela ezininzi. I-PCOS inokunyusa umngcipheko wokungachumi, isifo se-metabolic syndrome, i-apnea yokulala, umhlaza we-endometrium kunye noxinzelelo.

Ichongwa njani iPCOS

Oogqirha bahlala bechonga i-PCOS kwabasetyhini ubuncinci kwezi zimpawu zintathu ():

• amanqanaba aphezulu e-androgen
• imijikelo yokuya exesheni ngokungaqhelekanga
• ama-cysts kwii-ovari

Ugqirha wakho kufuneka abuze nokuba ngaba uneempawu ezinjenge-acne, ukukhula komzimba kunye nokukhula kweenwele, kunye nokuzuza ubunzima.

A Uvavanyo lwe-pelvic unokujonga naziphi na iingxaki ngamaqanda akho okanye ezinye iinxalenye zendlela yakho yokuzala. Ngethuba lovavanyo, ugqirha wakho ufaka iminwe egluvu kwilungu lakho lobufazi kwaye ujonge nakuphi na ukukhula kwisibeleko sakho okanye kwisibeleko.

Uvavanyo lwegazi jonga amanqanaba aphezulu kunalawo aqhelekileyo eehomoni zesilisa. Unokuba novavanyo lwegazi ukujonga i-cholesterol yakho, i-insulin, kunye namazinga e-triglyceride ukuvavanya umngcipheko weemeko ezinxulumene nesifo senhliziyo nesifo sikashukela.

An Ultrasound isebenzisa amaza esandi ukukhangela iifollic ezingaqhelekanga kunye nezinye iingxaki ngamaqanda akho kunye nesibeleko.

Oogqirha bachonga i-PCOS ukuba abasetyhini banobuncinci beempawu ezintathu eziphambili- amanqanaba aphezulu e-androgen, amaxesha angaqhelekanga, kunye nee-cysts kwii-ovari. Uvavanyo lwe-pelvic, uvavanyo lwegazi, kunye ne-ultrasound kunokuqinisekisa ukuxilongwa.

Ukukhulelwa kunye nePCOS

I-PCOS iphazamisa umjikelo oqhelekileyo wokuya exesheni kwaye yenza ukuba kube nzima ukukhulelwa. Phakathi kwama-70 ukuya kuma-80 epesenti yabasetyhini abane-PCOS baneengxaki zokuzala ().

Le meko inokunyusa umngcipheko wokukhulelwa.

Abasetyhini abane-PCOS banamathuba aphindwe kabini kunabafazi ngaphandle kwemeko yokuhambisa umntwana wabo ngaphambi kwexesha. Bakwasemngciphekweni omkhulu wokuphuma kwesisu, uxinzelelo lwegazi oluphezulu, kunye neswekile yokukhulelwa (19).

Nangona kunjalo, abasetyhini abane-PCOS banokukhulelwa besebenzisa unyango lokuchuma oluphucula i-ovulation. Ukuphulukana nobunzima kunye nokunciphisa amanqanaba eswekile yegazi kunokuphucula imeko yakho yokuba nokukhulelwa okunempilo.

I-PCOS inokwenza kube nzima ukukhulelwa, kwaye inokunyusa umngcipheko wokukhulelwa kunye nokuphuphuma kwesisu. Ukwehla kobunzima kunye nolunye unyango kunokuyiphucula indlela okhulelwe ngayo.

Ukutya kunye neengcebiso ngendlela yokuphila ukunyanga iPCOS

Unyango lwe-PCOS ihlala iqala ngotshintsho kwindlela ophila ngayo njengokulahleka kwesisindo, ukutya kunye nokuzilolonga.

Ukuphulukana ne-5 ukuya kwi-10 yeepesenti yobunzima bomzimba wakho kunokunceda ukulawula umjikelo wokuya esikhathini kunye nokuphucula iimpawu ze-PCOS (11,). Ukwehla kobunzima kunokuphucula amanqanaba e-cholesterol, ukunciphisa i-insulin, kunye nokunciphisa isifo sentliziyo kunye nomngcipheko wesifo seswekile.

Nakuphi na ukutya okukunceda ukunciphisa umzimba kunokunceda imeko yakho. Nangona kunjalo, ezinye izidlo zinokuba neenzuzo kunezinye.

Izifundo ngokuthelekisa ukutya kwi-PCOS zifumanise ukuba izidlo ezisezantsi ze-carbohydrate ziyasebenza kokubini ukunciphisa umzimba kunye nokunciphisa amanqanaba e-insulin. Isalathiso esisezantsi se-glycemic (low-GI) esifumana uninzi lweecarbohydrate kwiziqhamo, imifuno, kunye neenkozo ezipheleleyo kunceda ekulawuleni ixesha lokuya exesheni okungcono kunokutya okuqhelekileyo kokunciphisa umzimba (21).

Izifundo ezimbalwa zifumanise ukuba imizuzu engama-30 yokuzivocavoca umzimba ubuncinci ubuncinci iintsuku ezintathu ngeveki inokunceda abasetyhini abane-PCOS ukunciphisa umzimba. Ukunciphisa umzimba kunye nokuzilolonga kuphucula i-ovulation kunye namanqanaba e-insulin (22).

Ukuzilolonga kuluncedo ngakumbi xa kudityaniswe nokutya okusempilweni. Ukutya kunye nokuzilolonga kunceda ukuba unciphise ubunzima kunongenelelo kuphela, kwaye yehlisa umngcipheko wesifo seswekile kunye nesifo sentliziyo ().

Kukho ubungqina bokuba i-acupuncture inokunceda ekuphuculeni i-PCOS, kodwa uphando oluninzi luyafuneka ().

Unyango lwe-PCOS luqala ngotshintsho kwindlela yokuphila njengokutya nokuzilolonga. Ukuphulukana ne-5 ukuya kwi-10 yeepesenti yobunzima bomzimba wakho ukuba utyebe kakhulu kunokunceda ukuphucula iimpawu zakho.

Unyango oluqhelekileyo

Iipilisi zolawulo lokuzalwa kunye namanye amayeza anokunceda ekulawuleni umjikelo wokuya esikhathini kunye nokunyanga iimpawu zePCOS ezinje ngokukhula kweenwele kunye namabala.

Ukulawula inzala

Ukuthatha i-estrogen kunye neprogestin mihla le kunokubuyisela umlinganiso oqhelekileyo wehomoni, kulawule i-ovulation, kunciphise iimpawu ezinje ngokukhula kweenwele okweqile, kunye nokukhusela kumhlaza we-endometrium. Ezi hormone ziza kwipilisi, i-patch, okanye isangqa sangasese.

IMetformin

I-Metformin (iGlucophage, Fortamet) sisiyobisi esisetyenziselwa ukunyanga isifo seswekile sesi-2. Ikwanyanga i-PCOS ngokuphucula amanqanaba e-insulin.

Olunye uphononongo lufumanise ukuba ukuthatha i-metformin ngelixa usenza utshintsho kwindlela yokutya kunye nokuzilolonga kuphucula ukwehla kobunzima, kunciphisa iswekile yegazi, kwaye kubuyisela umjikelo oqhelekileyo wokuya exesheni ngcono kunotshintsho kwindlela yokutya nokuzilolonga kuphela (25).

Clomiphene

I-Clomiphene (Clomid) sisiyobisi esiza kunceda abantu basetyhini ukuba babe ne-PCOS ukuba bakhulelwe. Nangona kunjalo, yonyusa umngcipheko wamawele kunye nokunye ukuzalwa okuninzi (26).

Amayeza okususa iinwele

Unyango oluncinci lunokunceda ukulahla iinwele ezingafunekiyo okanye ukuyeka ukukhula. I-Eflornithine (Vaniqa) khrimu sisiyobisi esenziwa ngugqirha esicothisa ukukhula kweenwele. Ukususwa kweenwele zeLaser kunye ne-electrolysis kunokususa iinwele ezingafunekiyo ebusweni nasemzimbeni.

Ugqirha

Ugqirha lunokuba lukhetho lokuphucula ukuchuma ukuba olunye unyango alusebenzi. Ukombiwa kwe-Ovarian yinkqubo eyenza imingxunya emincinci kwi-ovary ene-laser okanye inaliti eshushu eshushu yokubuyisela i-ovulation yesiqhelo.

Iipilisi zolawulo lokuzalwa kunye nesifo seswekile i-metformin inokunceda ukubuyisa umjikelo oqhelekileyo wokuya exesheni. I-Clomiphene kunye notyando kuphucula ukuzala kwabasetyhini abane-PCOS. Amayeza okususa iinwele angasusa abasetyhini kwiinwele ezingafunekiyo.

Nini ukubona ugqirha

Jonga ugqirha wakho ukuba:

• Uphose amaxesha kwaye awukhulelwanga.
• Unempawu zePCOS, ezinje ngokukhula kweenwele ebusweni nasemzimbeni.
• Kudala uzama ukukhulelwa ngaphezulu kweenyanga ezili-12 kodwa khange uphumelele.
• Unempawu zesifo seswekile, ezinjengokunxanwa okanye indlala, umbono ongacacanga, okanye ukuncipha komzimba okungachazwanga.

Ukuba unayo i-PCOS, cwangcisa ukutyelela rhoqo kunye nogqirha wakho wokunyamekela. Uya kudinga iimvavanyo rhoqo ukujonga isifo seswekile, uxinzelelo lwegazi oluphezulu, kunye nezinye iingxaki ezinokubakho.

Ukuba unenkxalabo malunga ne-PCOS yakho kwaye ungenayo i-endocrinologist, unokujonga oogqirha kwindawo yakho ngokusebenzisa isixhobo seHealthline FindCare.

Jonga ugqirha wakho ukuba utyeshele amaxesha okanye unezinye iimpawu zePCOS ezinje ngokukhula kweenwele ebusweni okanye emzimbeni. Kwakhona ubone ugqirha ukuba uzama ukukhulelwa iinyanga ezili-12 okanye ngaphezulu ngaphandle kwempumelelo.

Umgca wezantsi

I-PCOS inokuphazamisa ukuhamba komfazi kwaye yenza kube nzima ukukhulelwa. Amanqanaba aphezulu ehomoni yamadoda akhokelela kwiimpawu ezingafunekiyo njengokukhula kweenwele ebusweni nasemzimbeni.

Ungenelelo ngobomi bendlela yokuqala yokucebisa oogqirha ngePCOS, kwaye zihlala zisebenza kakuhle. Ukuphulukana nobunzima kunokunyanga iimpawu ze-PCOS kunye nokuphucula imeko yokukhulelwa. Ukutya kunye nokuzivocavoca umzimba ngeendlela ezimbini ezifanelekileyo zokunciphisa umzimba.

Amayeza anokukhetha ukuba utshintsho kwindlela yokuphila alusebenzi. Iipilisi zolawulo lokuzalwa kunye ne-metformin zombini zinokubuyisela imijikelezo yesiqhelo yokuya exesheni kwaye zinciphise iimpawu ze-PCOS.