I-Sargramostim

Umxholo

• Ngaphambi kokusebenzisa inaliti yesargramostim,
• I-Sargramostim inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Sargramostin isetyenziselwa ukunciphisa amathuba okusuleleka kubantu abane-leukemia (myl) kunye nohlobo lomhlaza weeseli ezimhlophe zegazi) kwaye bafumana amayeza e-chemotherapy anokunciphisa inani le-neutrophils (uhlobo lweseli yegazi ekufuneka ilwelwe usulelo). I-Sargramostin ikwasetyenziswa nakubantu abafumana ukufakelwa iiseli ze-stem zegazi, kubantu abafakwa utyando lomongo wethambo, kunye nokulungiselela igazi leukapheresis (unyango apho iiseli ezithile zegazi zisuswe emzimbeni zaze zabuyela emzimbeni olandelayo ichemotherapy). I-Sargramostim iphinda isetyenziswe kubantu abangaphendulanga emva kokufumana ukufakelwa komongo wegazi. USargramostin ukwiklasi yamayeza abizwa ngokuba zizinto ezikhuthaza ikoloni. Isebenza ngokunceda umzimba wenze ii-neutrophils ezingakumbi kunye nezinye iiseli zegazi.

I-Sargramostim iza njengesisombululo (ulwelo) okanye umgubo oxutywe nolwelo ukufaka inaliti (phantsi kolusu) okanye ngaphakathi ngaphakathi (emthanjeni). Ukufakwa (ukufakwa kancinci) ngaphezulu kweeyure ezingama-2 ukuya kwezi-24 kanye yonke imihla. Inokujojowe ngendlela engaphantsi kube kanye yonke imihla. Ubude bonyango lwakho buxhomekeke kwimeko onayo kunye nendlela ophendula ngayo emzimbeni wakho kunyango.

Ukuba usebenzisa i-sargramostim ukunciphisa umngcipheko wosulelo ngexesha le-chemotherapy, uyakufumana amayeza ubuncinci kwiintsuku ezi-4 emva kokufumana idosi yokugqibela yomjikelo ngamnye wekhemotherapy. Uya kuqhubeka nokufumana amayeza yonke imihla de ukubala kweeseli zakho zegazi kubuyele esiqhelweni okanye ukuya kuthi ga kwiiveki ezi-6. Ukuba usebenzisa i-sargramostim ukulungiselela igazi lakho kwi-leukapheresis, uyakufumana iyeza kanye yonke imihla kude kube yi-leukapheresis yokugqibela. Ukuba usebenzisa i-sargramostim ngenxa yokuba utyando lwe-cell stem, uya kufumana amayeza ukuqala ngomhla wokufakelwa kweseli yegazi kwaye uqhubeke ubuncinci iintsuku ezi-3. Ukuba usebenzisa i-sargramostim ukunciphisa umngcipheko wosulelo ngexesha lofakelo lomongo wethambo, uyakufumana amayeza ubuncinci kwiiyure ezingama-24 emva kokuba ufumene ichemotherapy kwaye kwakhona iiyure ezi-2 ukuya kwezi-4 emva kokuba umongo wethambo ungenisiwe. Ukuba usebenzisa i-sargramostim kuba awuphenduli kufakelo lomongo wethambo, uyakufumana amayeza kanye ngemini kangangeentsuku ezili-14. Sukuyeka ukusebenzisa i-sargramostim ungakhange uthethe nogqirha wakho.

ISargramostim inganikwa ngumongikazi okanye ngomnye umboneleli wezempilo, okanye usenokuxelelwa ukuba utofe iyeza ekhaya. Ukuba uza kutofa i-sargramostim ,joza amayeza malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-sargramostim ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ukuba uya kutofa i-sargramostim ngokwakho, umboneleli wezempilo uya kukubonisa ukuba ungalitofa njani iyeza. Qiniseka ukuba uyayiqonda le ndlela. Buza umboneleli wakho wezempilo ukuba unayo nayiphi na imibuzo malunga nokuba uphi emzimbeni wakho kufuneka utofe i-sargramostim, indlela yokufaka inaliti, loluphi uhlobo lwesirinji oyisebenzisayo, okanye indlela yokulahla iinaliti kunye neesirinji ezisetyenzisiweyo emva kokuba utofile iyeza.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

I-Sargramostim ngamanye amaxesha isetyenziselwa ukunyanga iintlobo ezithile zesifo se-myelodysplastic (iqela leemeko apho umongo wethambo uvelisa iiseli zegazi ezingafakwanga kakuhle kwaye zingavelisi iiseli zegazi ezaneleyo) kunye ne-aplastic anemia (imeko apho umongo wethambo ungenawo ukuvelisa iiseli ezintsha zegazi). I-Sargramostim ngamanye amaxesha isetyenziselwa ukunciphisa amathuba okusuleleka kubantu abane-virus ye-immunodeficiency virus (HIV). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yesargramostim,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-sargramostim, igwele, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ze-sargramostim. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya i-betamethasone (iCelestone), i-dexamethasone (i-Decadron), i-lithium (i-Lithobid), i-methylprednisolone (i-Medrol) kunye ne-prednisone.Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba uyanyangwa okanye ukuba ukhe wanyangwa ngonyango lwe-radiation okanye ukuba wakhe wanomhlaza okanye i-edema (ukudumba kwesisu, iinyawo, amaqatha, okanye imilenze esezantsi), naluphi na uhlobo lwesifo sentliziyo, ukusilela kwentliziyo , ukubetha kwentliziyo okungaqhelekanga, imiphunga, izintso, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa i-sargramostim, tsalela umnxeba ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-sargramostim.
• Kuya kufuneka uyazi ukuba i-sargramostim inciphisa umngcipheko wosulelo, kodwa ayithinteli lonke usulelo olunokuthi lukhule ngexesha okanye emva kwechemotherapy. Biza ugqirha wakho kwangoko ukuba uvela kwiimpawu zosulelo ezifana nomkhuhlane, ukugodola, umqala obuhlungu, okanye ukukhohlela okuqhubekayo kunye nokudibana.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Sargramostim inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ububomvu, ukudumba, ukugruzuka, ukurhawuzelela okanye iqhuma kwindawo apho lalifakwe khona iyeza
• intlungu, ukudibanisa, okanye intlungu yomzimba
• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• urhudo
• isisu esibuhlungu
• izilonda zomlomo
• Ukuphelelwa ngumdla wokutya
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukuphefumla kancinci okanye ukuphefumla ngokukhawuleza
• ubunzima bokuphefumla
• ukuvutha
• isiyezi
• ukubila
• urhwebo
• irhashalala
• ukurhawuzelela
• ukudumba ujikeleze umlomo, ubuso, amehlo, isisu, iinyawo, amaqatha okanye imilenze esezantsi
• ukukhawuleza ukutyeba
• iintlungu zesifuba
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• isiqaqa
• ukugruzuka okungaqhelekanga okanye uphawu olubomfusa phantsi kolusu
• ukopha okungaqhelekanga
• impumlo
• ukudinwa okungaqhelekanga okanye ubuthathaka
• ukuncipha kokuchama

I-Sargramostim inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisitya esifikileyo, kude nelanga, livaliwe, kwaye lingenakufikelela ebantwaneni. Gcina i-sargramostim kwifriji. Musa ukumisa ngumkhenkce okanye ugungqise i-sargramostim. Iibhotile ezivulwe sargramostim zinokufakwa efrijini ukuya kuthi ga kwiintsuku ezingama-20. Ukulahla iibhotile ezivuliweyo emva kweentsuku ezingama-20.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukuqhawukelwa ngumphefumlo
• ukudinwa okungaqhelekanga okanye ubuthathaka
• ifiva
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• isicaphucaphu
• intloko ebuhlungu
• irhashalala

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga impendulo yomzimba wakho kwi-sargramostim.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ileukine^®

• IGranulocyte-Macrophage Colony-ekhuthazayo yeFactor
• GM-CSF