Isiseko seParathyroidism

Umxholo

• Zithini iimpawu zentsholongwane egazini?
• Yintoni ebangela i-hyperparathyroidism ephambili?
• Adenoma
• Ukwandiswa kweengqungquthela zeParathyroid
• Umhlaza weParathyroid
• Ifunyaniswa njani i-hyperparathyroidism ephambili?
• Unyango olusisiseko anyangwa njani?
• Ukuthatha

Yintoni iphrayparathyroidism ephambili?

Iingqungquthela ze-parathyroid zincinci ezine ezincinci ezikufutshane okanye emva kwe-thyroid engaphantsi kwe-apula ka-Adam. (Ewe, abafazi banayo i-apile ka-Adam. Incinci nje kuneyendoda.) Ezi zidlala zivelisa i-hormone ye-parathyroid (PTH).

Amadlala e-parathyroid alawula amanqanaba e-calcium, i-phosphorus, kunye ne-vitamin D emzimbeni. Eyona nto ibangela ukukhutshwa okanye ukuveliswa kwe-PTH linqanaba lecalcium egazini. I-PTH inceda ukulawula inani le-calcium emzimbeni. Ukuba inqanaba lakho le-calcium liba sezantsi kakhulu, i-PTH inceda ukuzisa i-calcium egazini lakho. Ikwenza oku ngokwandisa ukubuyisela kwakhona i-calcium emathunjini nasemathanjeni. I-PTH ikwanciphisa inani lecalcium elahlekileyo kumchamo.

Izibilini zakho ze-parathyroid zihlala zincinci kakhulu. Ngokuqhelekileyo malunga nobungakanani bengqolowa enye yerayisi. Ngamanye amaxesha, idlala elinye okanye nangaphezulu liyanda. Ivelisa i-PTH eninzi kakhulu.Ngamanye amaxesha, ukukhula kwelinye lala malungu kunokubangela ukuba kuvelise inani elonyukayo le-PTH.

I-PTH eninzi ikhokelela kwi-calcium eninzi egazini lakho. Le meko ibizwa ngokuba yi-hypercalcemia. Ingabangela iimpawu ezahlukeneyo, kubandakanya:

• ukuchama rhoqo
• iingxaki zesisu
• ukudideka
• ukudinwa

Zithini iimpawu zentsholongwane egazini?

I-hyperparathyroidism yaseprayimari ihlala ingenazimpawu. Ukuba iimpawu zikhona, zihlala zilula kakhulu. I-hyperparathyroidism yaseprayimari ifunyanwa ikakhulu kwabasetyhini abasemva kwemini, ngokutsho kophando olupapashwe kwiJenali yeLizwe ye-Endocrinology. Uxinzelelo lwegazi oluphezulu luhlala luhamba ne-hyperparathyroidism. Xa uphatha i-hyperparathyroidism yakho, uxinzelelo lwegazi luya kuthi lwehle.

Iimpawu ezenzeka nge-hyperparathyroidism zihlala zingacacanga. Oku kuthetha ukuba ababikho bodwa kule meko. Umzekelo, unokufumana:

• ubuthathaka bemisipha
• ukungakhathali
• ukudinwa
• intlungu kwimisipha yakho
• ukudakumba

Ukuba imeko yakho imbi kakhulu, unokufumana:

• amatye ezintso, ngenxa
• ukuchama rhoqo
• isisu, okanye isisu, iintlungu
• isicaphucaphu nokugabha
• ukudideka
• imemori ephazamisekileyo
• utshintsho kubuntu
• ukuqhina
• ukunciphisa amathambo kunye nokuqhekeka
• isiqaqa (kwiimeko ezinqabileyo)

Yintoni ebangela i-hyperparathyroidism ephambili?

I-hyperparathyroidism yaseprayimari yenzeka xa amadlala akho e-parathyroid evelisa i-PTH kakhulu. Iimeko ezahlukeneyo zinokubangela i-hyperparathyroidism, enje ngezi zilandelayo.

Adenoma

I-adenoma sisifo esingenamhlaza kwelinye lala madlala. Ezi tumors zezona zizathu zixhaphakileyo ze-hyperparathyroidism.

Ukwandiswa kweengqungquthela zeParathyroid

Ngamanye amaxesha, ukonyusa ubuncinci bamadlala akho e-parathyroid kungakhokelela kwi-hyperparathyroidism. Oogqirha bahlala bengazi ukuba yintoni ebangela oku kwandiswa.

Umhlaza weParathyroid

Kwiimeko ezinqabileyo, umhlaza weparathyroid unokubangela ukwanda kwesinye okanye nangaphezulu kwamadlala okubamba. Ezi tumors zinokubangela i-hyperparathyroidism.

Ifunyaniswa njani i-hyperparathyroidism ephambili?

I-hyperparathyroidism yaseprayimari ifunyaniswa ngokubanzi kuvavanyo lwegazi. Iimpawu zale meko zibandakanya:

• PTH ephakamileyo
• i-calcium ephezulu yegazi
• i-alkaline phosphatase ephezulu, iprotein efumaneka kwithambo nakwisibindi
• amanqanaba asezantsi e-phosphorus

Xa ugqirha wakho ekrokrela i-hyperparathyroidism, baya kujonga ukuxinana kwethambo lakho. Ukuba ne-PTH eninzi kunyusa amanqanaba e-calcium egazini lakho. Umzimba wakho utsala le calcium emathanjeni akho. IX-reyi inokunceda ugqirha wakho achonge iingxaki zethambo, ezinje ngokuqhekeka kunye nokubhitya.

Unyango olusisiseko anyangwa njani?

Ubukrakra be-hyperparathyroidism ephambili bunokwahluka kakhulu. Akukho khosi enye yonyango efanelekileyo kuwo onke amatyala. Ugqirha wakho uya kusebenza nawe ukuze afumanise ukuba yintoni efanelekileyo kwimeko yakho.

Ukuba awunayo nayiphi na impawu, unokungafuneki unyango olukhawulezileyo. Endaweni yoko, ugqirha wakho unokujonga nje imeko yakho ukuze aqiniseke ukuba ayibi mbi. Banokubeka iliso:

• amanqanaba e-calcium
• umsebenzi wezintso
• uxinano lwethambo
• ingaba sele uqalile ukuphuhlisa amatye ezintso

Ukuba ufuna unyango, utyando lolona khetho luqhelekileyo lonyango kwaye lukhokelela kunyango phantse kuzo zonke iimeko. Kuphela ngamadlala achaphazelekayo asuswe. Ukuba onke amadlala ayandisiwe, isahlulo esinye sedlala siya kushiyeka emzimbeni ukuze ube usenazo izicwili zeparathyroid ezisebenzayo.

Ugqirha wakho unokucebisa utyando ukuba:

• inqanaba lakho lecalcium lingaphezulu kwe-1.0 milligram yedesilitha nganye (mg / dL) ngaphezulu kohlobo oluqhelekileyo lwe-8.5-10.2 mg / dL, nangaphandle kwempawu
• Ukuxinana kwethambo lakho kusezantsi kakhulu
• uneempawu ezinxulumene nenqanaba eliphezulu lecalcium
• ungaphantsi kweminyaka engama-50 ubudala

Ngamanye amaxesha amayeza ayacetyiswa ukunceda ukuthintela ezinye zeengxaki ezinxulumene ne-hyperparathyroidism ephambili. Njengokuba:

• I-Bisphosphonates, efana ne-alendronate (Fosamax), inceda ukunciphisa ukuhla kwethambo.
• ICinacalcet (iSensipar) inceda ukubuyisela amanqanaba e-calcium egazini.

Unyango lwe-Estrogen lunokumiselwa kubantu basetyhini abasemva kwemini.

Ukuthatha

I-Hyperparathyroidism yimeko xa amadlala akho e-parathyroid evelisa i-hormone eninzi kakhulu emzimbeni wakho. Oku kubangela ukuba amanqanaba akho e-calcium anyuke, anokukhokelela ekunciphiseni kwamathambo kunye nokwaphuka, iingxaki zesisu kunye noxinzelelo. Rhoqo akukho zimpawu zokuqala. Ukuba unyango luyimfuneko, unyango luyacetyiswa kwaye luhlala lunyanga.