Ngaba kukhuselekile ukuxuba iiStatins kunye notywala?

Umxholo

• Iziphumo ebezingalindelekanga zeStatin
• Ukudumba kwesibindi
• Intlungu yezihlunu
• Ezinye iziphumo ebezingalindelekanga
• Ukusela utywala ngelixa ukwi-statins

Ushwankathelo

Kuwo onke amayeza athoba i-cholesterol, ii-statins zezona zisetyenziswa kakhulu. Kodwa la machiza akezi ngaphandle kwemiphumo emibi. Kwaye kwabo bantu bonwabela isiselo esinxilisayo ngamaxesha athile (okanye rhoqo), iziphumo ebezingalindelekanga kunye neengozi zinokwahluka.

Iitatins zodidi lweziyobisi ezisetyenziselwa ukunceda ukunciphisa i-cholesterol. Ngokwengxelo, iipesenti ezingama-93 zabantu abadala base-US bathatha amayeza e-cholesterol ngo-2012 babethatha istin. Ii-Statins ziphazamisa imveliso yomzimba we-cholesterol kwaye zinceda ukunciphisa i-lipoproteins ezixineneyo (LDLs), okanye i-cholesterol embi, xa ukutya kunye nokuzilolonga kungakhange kubonakale kusebenza.

Iziphumo ebezingalindelekanga zeStatin

Amayeza amiselweyo onke eza neziphumo ebezingalindelekanga, okanye umngcipheko weziphumo ebezingalindelekanga. Ngama-statins, uluhlu olude lweziphumo ezinokubangela abanye abantu ukuba babuze ukuba kufanelekile urhwebo.

Ukudumba kwesibindi

Ngamaxesha athile, ukusetyenziswa kwe-statin kunokuchaphazela impilo yesibindi. Nangona kunqabile, ii-statins zinokunyusa imveliso ye-enzyme yesibindi. Kwiminyaka eliqela eyadlulayo, i-FDA yacebisa ukuvavanywa kwe-enzyme rhoqo kwizigulana ze-statin. Kodwa ngenxa yokuba umngcipheko wokulimala kwesibindi unqabile, oku akusekho njalo. Indima yesibindi kwimetabolism yotywala kuthetha ukuba abo basela kakhulu banokuba semngciphekweni omkhulu, nangona kunjalo.

Intlungu yezihlunu

Iziphumo eziqhelekileyo zecala lokusetyenziswa kwe-statin intlungu yesisu kunye nokuvuvukala. Ngokubanzi, oku kuvakalelwa kukubandezeleka okanye ubuthathaka bemisipha. Kwiimeko ezimbi kakhulu, kunokukhokelela kwi-rhabdomyolysis, imeko esongela ubomi enokubangela ukonakala kwesibindi, ukusilela kwezintso, okanye ukufa.

Ukuya kuthi ga kwiipesenti ezingama-30 zabantu abafumana iintlungu zemisipha kusetyenziswa i-statin. Kodwa phantse bonke bafumanisa ukuba xa betshintshela kwi-statin eyahlukileyo, iimpawu zabo zisonjululwa.

Ezinye iziphumo ebezingalindelekanga

Iingxaki zokugaya ukutya, irhashalala, ukugungxula, ukungalawuleki kakuhle kweglucose, kunye nemicimbi yememori kunye nokudideka zizinye iziphumo ebezingalindelekanga ezixeliweyo.

Ukusela utywala ngelixa ukwi-statins

Ngokubanzi, akukho mngcipheko othile wezempilo onxulunyaniswa nokusela ngelixa usebenzisa ii-statins. Ngamanye amagama, utywala abuzukuphazamisa kwangoko okanye busabele kwi-statins emzimbeni wakho. Nangona kunjalo, abo basela kakhulu okanye abo sele benomonakalo wesibindi ngenxa yokusela kakhulu banokuba semngciphekweni omkhulu wokufumana iziphumo ebezingalindelekanga ezibi kakhulu.

Kuba ukusela kakhulu kunye (kwaye kunqabile) ukusetyenziswa kwe-statin kunokuphazamisa ukusebenza kwesibindi, bobabini ngokudibeneyo banokubeka abantu emngciphekweni omkhulu weengxaki zempilo ezinxulumene nesibindi.

Imvumelwano ngokubanzi kukuba ukusela ngaphezulu kweziselo ezimbini ngosuku ngamadoda kunye nesiselo esinye ngemini kubafazi kunokukubeka emngciphekweni omkhulu wesifo sesibindi esinotywala kunye neziphumo ebezingalindelekanga ezinokubakho.

Ukuba unembali yokusela kakhulu okanye ukonakala kwesibindi, ukusilela ukukhupha isihloko xa ugqirha wakho eqala ukucebisa ukuba ii-statins zinokuba yingozi. Ukwazisa ugqirha wakho ukuba ukhe wakho okanye kungoku nje usela kakhulu uya kubalumkisa ukuba bafune ezinye iindlela okanye babeke esweni ukusebenza kwesibindi ngeempawu zomonakalo.