Unyango lwe-Ulcerative Colitis

Umxholo

• Ukudumba okwenziwa sisilonda sikabhobhosi
• Ukutya kunye nesondlo
• Ulawulo loxinzelelo
• Amayeza
• Aminosalicylates
• ICorticosteroids
• Amagciwane omzimba
• Ibhayoloji
• Ugqirha
• Yise kude

Ukudumba okwenziwa sisilonda sikabhobhosi

Ukujamelana ne-ulcerative colitis kunokuzisa umngeni.

Isifo esinganyangekiyo, esichaphazela abantu abamalunga nesigidi e-United States, sibangela ukudumba kunye nezilonda kuludwe lwekholoni kunye ne-rectum.

Njengoko ukudumba kuya kusiba kubi, iiseli ezihambelana nale mimandla ziyafa, zikhokelela ekuphumeni kwegazi, usulelo kunye nohudo.

Le meko inokubangela:

• ifiva
• ianemia
• ukudinwa
• intlungu edibeneyo
• ukungabi namdla wokutya
• ukuhla ukusinda
• izilonda zolusu
• ukunqongophala kwesondlo
• ukukhula okungaginyisi mathe ebantwaneni

Oyena nobangela wokudumba okwenziwa sisilonda sikabhobhosi akucaci. Iingcali ezininzi zikholelwa ukuba zibangelwa kukungaqheleki kwenkqubo yomzimba yokuzikhusela nokungakwazi ukuphatha iintsholongwane kwindawo yokugaya ukutya.

Ugqirha wakho unokucela uvavanyo lwegazi, iisampuli zestool, i-enema ye-barium, kunye ne-colonoscopy. Olu vavanyo lonyango luya kubavumela ukuba babone ukuba ngaba i-ulcerative colitis ibangela iimpawu zakho okanye iimpawu zakho zibangelwa yenye imeko efana nesifo sikaCrohn, isifo esingafaniyo, okanye umhlaza.

I-ulcerative colitis kufuneka iqinisekiswe yi-biopsy yethishu ngexesha le-colonoscopy.

Ukuba ufunyaniswe une-ulcerative colitis, kubalulekile ukusebenza nomboneleli wakho wezempilo ukwenza isicwangciso sonyango esilawula kwaye sithintele uhlaselo ukuze ikholoni yakho iphilise.

Ngenxa yokuba iimpawu kunye neziphumo zesifo ziyahluka, akukho lunyango lunye lusebenzela wonke umntu. Unyango luhlala lujolise:

• ukutya kunye nesondlo
• inqanaba loxinzelelo
• amayeza

Ukutya kunye nesondlo

Kungcono ukusebenzisa izixa ezincinane zokutya imini yonke. Gwema ukutya okuluhlaza kunye nokutya okuphezulu ukuba oku kukutya okuyingxaki kuwe. Imizekelo yokutya okunokuphetshwa nge-UC ibandakanya:

• amandongomane
• iimbewu
• iimbotyi
• amazimba

Ukutya okunamafutha kunye nokunamafutha nako kunegalelo kukudumba kunye nentlungu. Ngokubanzi, ukutya okukhuselekileyo kubandakanya:

• iinkozo ifayibha ephantsi
• inkuku ebhakaweyo, inyama yehagu, nentlanzi
• iziqhamo ezijiweyo / ezibhakiweyo okanye imifuno

Ukuhambisa amanzi imini yonke kunokunceda ekucoleni ukutya kwaye kuncede ukunciphisa ukudumba. Funda ngakumbi malunga nokutya okunokunceda abantu abane-UC.

Ulawulo loxinzelelo

Ixhala kunye novalo lunokuzenza mandundu iimpawu. Ukuzivocavoca kunye neendlela zokuphumla ezikunceda ukulawula kunye nokunciphisa amanqanaba oxinzelelo kunokuba luncedo. Oku kubandakanya:

• biofeedback
• ukuphulula
• ukucamngca
• unyango

Luluphi unxibelelwano phakathi koxinzelelo kunye ne-UC flareups?

Amayeza

Ugqirha wakho unokukunika amayeza ukunyusa okanye ukugcina uxolelo. Nangona iindidi zamayeza zikhona, iyeza ngalinye liwela kwiindidi ezine eziphambili.

Aminosalicylates

La machiza ane-5-aminosalicyclic acid (5-ASA), enceda ukulawula ukudumba emathunjini.

Ii-Aminosalicylates zinokulawulwa:

• ngomlomo
• ngokusebenzisa i-enema
• kwindawo yokugcina izinto

Ngokwesiqhelo bathatha iiveki ezi-4 ukuya kwezi-6 ukusebenza. Nangona kunjalo, zinokubangela iziphumo ebezingalindelekanga, kubandakanya:

• isicaphucaphu
• ukugabha
• isilungulela
• urhudo
• intloko ebuhlungu

ICorticosteroids

Eli qela lamachiza e-steroid-kubandakanya i-prednisone, budesonide, methylprednisolone, kunye ne-hydrocortisone-inceda ukunciphisa ukudumba.

Zisoloko zisetyenziswa ukuba uhlala ne-ulcerative colitis esezingeni eliphakathi, kubandakanya ukuba awuphendulanga kakuhle kumachiza ama-5-ASA.

ICorticosteroids inokulawulwa ngomlomo, ngaphakathi, nge-enema, okanye kwindawo yokugcina izinto. Iziphumo ziquka:

• induna
• iinwele zobuso
• uxinzelelo lwegazi
• isifo seswekile
• ukutyeba kwakho
• ukuhamba kweemvakalelo
• ukulahleka kwamathambo
• ukwanda kwengozi yosulelo

I-Steroids isetyenziswe ngokufanelekileyo kwixesha elifutshane ukunciphisa imiphumo ye-ulcerative colitis flare-up, kunokuba njengonyango lwemihla ngemihla ukulawula iimpawu.

Xa ulcerative colitis inzima kakhulu, ugqirha wakho unokumisela idosi yemihla ngemihla ye-steroids ukukunceda ugcine indlela yokuphila eqhelekileyo.

Amagciwane omzimba

La machiza, kubandakanya i-azathioprine kunye ne-6-mercapto-purine (6-MP), anceda ukunciphisa ukudumba kwamajoni omzimba- nangona angathatha ixesha elingangeenyanga ezi-6 ukusebenza ngokukuko.

Ama-immunomodulators alawulwa ngomlomo kwaye asetyenziswa ngokuqhelekileyo ukuba awuphenduli ngokufanelekileyo kwindibaniselwano ye-5-ASAs kunye ne-corticosteroids. Iziphumo ezinokubakho zibandakanya:

• ukudumba komzimba
• hepatitis
• kunciphise inani leeseli ezimhlophe
• ukwanda kwengozi yosulelo

Ibhayoloji

Olu luhlobo olutsha lwamachiza asetyenziswa njengenye indlela yokunyanga ii-immunomodulators ukunyanga ulcerative colitis kubantu abangaphendulanga kakuhle kolunye unyango.

I-Biologics iyinkimbinkimbi kwaye ijolise kwiiprotheni ezithile. Banokunikwa ngokufakwa ngaphakathi okanye ngenaliti. Okwangoku, kukho amayeza e-biologic avunyiweyo e-FDA kunyango lwe-ulcerative colitis:

• Tofacitinib (Xeljanz)
• adalimumab (Humira)
• igolimumab (iSimponi)
• infliximab (I-Remicade)
• vedolizumab (Entyvio)

Fumana ngakumbi malunga nokusebenzisa i-biologics ukunyanga okuphakathi ukuya kwi-UC ebukhali.

Ugqirha

Ukuba ezinye iindlela zonyango azisebenzi, unokuba ngumgqatswa wotyando.

Abanye abantu abane-UC ekugqibeleni banquma ukuba iikholoni zabo zisuswe ngenxa yokuphuma kwegazi kunye nokugula-okanye ukwanda komngcipheko womhlaza.

Zine iindidi zotyando ezikhoyo:

• Ukubuyisela kwakhona i-proctocolectomy kunye ne-ileal poch-anal anastomosis
• I-colectomy yesisu iyonke kunye ne-ileorectal anastomosis
• I-colectomy yesisu iyonke kunye ne-ileostomy yokuphela
• Iproctocolectomy iyonke kunye ne-ileostomy yokuphela

Ukuba une-ulcerative colitis, thintela amachiza angenayo i-nonsteroidal anti-inflammatory (NSAIDs), anokwenza iimpawu zibe mandundu.

Thetha nogqirha wakho ukwenza isicwangciso sonyango esiza kujongana neemfuno zakho zokhathalelo lwempilo.

Kwakhona, ngenxa yomngcipheko owandileyo womhlaza onxulunyaniswa nesifo sezilonda esibuhlungu, cwangcisa uviwo rhoqo ngonyaka okanye yonke iminyaka emi-2, ngengcebiso kagqirha wakho.

Ngendlela elungileyo, kunokwenzeka ukuba ulawule i-ulcerative colitis kwaye uphile ngendlela eqhelekileyo.

Kwenzeka ntoni ukuba awufuni unyango kwi-UC?

Yise kude

I-ulcerative colitis ingaba ngumngeni ukunyanga. Nangona kunjalo, kukho iindlela ezahlukeneyo zonyango ezikhoyo.

Thetha nogqirha wakho malunga neempawu zakho. Ngokudibeneyo ningavelisa isicwangciso sonyango esisebenza ngcono kuwe.