Yenza uvavanyo lwephosphokinase

Yenza i-phosphokinase (CPK) yi-enzyme emzimbeni. Ifunyanwa ikakhulu entliziyweni, kwingqondo nakwisipha samathambo. Eli nqaku lixoxa ngovavanyo lokulinganisa isixa se-CPK egazini.

Isampulu yegazi iyafuneka. Oku kungathathwa kumthambo. Inkqubo ibizwa ngokuba yi-venipuncture.

Olu vavanyo lunokuphindaphindwa ngaphezulu kweentsuku ezi-2 okanye ezi-3 ukuba isigulana usesibhedlele.

Akukho lungiselelo lukhethekileyo luyafuneka kumaxesha amaninzi.

Xelela umboneleli wakho wezempilo nangawo nawaphi na amayeza owasebenzisayo. Iziyobisi ezinokunyusa imilinganiselo ye-CPK zibandakanya i-amphotericin B, i-anesthetics ethile, i-statins, i-fibrate, i-dexamethasone, utywala kunye necocaine.

Unokuva iintlungu kancinci xa kufakwa inaliti ukutsala igazi. Abanye abantu baziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukuthotywa okuthile.

Xa inqanaba elipheleleyo le-CPK liphezulu kakhulu, ihlala ithetha ukuba kubekho ukulimala okanye uxinzelelo kwizicubu zomzimba, intliziyo, okanye ingqondo.

Ukulimala kwezihlunu zemisipha kunokwenzeka. Xa umsipha wonakele, i-CPK iyavuza kwigazi. Ukufumana ukuba loluphi uhlobo lwe-CPK oluphezulu kunceda ekuboneni ukuba zeziphi izicwili ezonakalisiweyo.

Olu vavanyo lunokusetyenziselwa:

• Ukuchonga isifo sentliziyo
• Vavanya unobangela wentlungu yesifuba
• Chonga ukuba ngaba isihlunu sonakaliswe kangakanani na
• Khangela i-dermatomyositis, i-polymyositis kunye nezinye izifo zezihlunu
• Xelela umahluko phakathi kwehyperthermia enobungozi kunye nosulelo lwasemva kokusebenza

Ipateni kunye nexesha lokunyuka okanye ukwehla kwamanqanaba e-CPK kunokuba kubalulekile ekwenzeni isifo. Oku kuyinyani ngakumbi ukuba kurhanelwa isifo sentliziyo.

Kwiimeko ezininzi ezinye iimvavanyo zisetyenziselwa endaweni okanye kolu vavanyo ukufumanisa isifo sentliziyo.

Ixabiso elipheleleyo le-CPK:

• I-10 ukuya kwi-120 micrograms kwilitha nganye (mcg / L)

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Amanqanaba aphezulu e-CPK anokubonwa kubantu abane:

• Ukulimala kwengqondo okanye ukubetha
• Ukuxhuzula
• I-Delirium inyikima
• Dermatomyositis okanye polymyositis
• Umothuko wombane
• Ukuhlaselwa yintliziyo
• Ukudumba kwentliziyo yemisipha (myocarditis)
• Ukufa kwamathambo emiphunga (i-pulmonary infarction)
• Izihlunu zemisipha
• Unyango
• Ukuhlaziywa kweRhabdomyolysis

Ezinye iimeko ezinokunika iziphumo zovavanyo ezilungileyo zibandakanya:

• IHypothyroidism
• Hyperthyroidism
• I-Pericarditis ilandela isifo sentliziyo

Iingozi ezinxulumene nokutsalwa kwegazi zincinci kodwa zinokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Olunye uvavanyo kufuneka lwenziwe ukufumana eyona ndawo yomonakalo wemisipha.

Izinto ezinokuthi zichaphazele iziphumo zovavanyo zibandakanya i-catheterization yentliziyo, inaliti ye-intramuscular, trauma to muscle, utyando lwamva nje, kunye nokuzilolonga okunzima.

Uvavanyo lweCPK

• Uvavanyo lwegazi

UAnderson JL. Icandelo lokuphakama kwinqanaba eliphakamileyo le-myocardial infarction kunye neengxaki ze-myocardial infarction. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 73.

ICarty RP, iPincus MR, uSarafraz-Yazdi E.I-enzymology yeklinikhi. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 20.

IMccullough PA. Unxibelelwano phakathi kwesifo sezintso kunye nesifo sentliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 98.

INagaraju K, Gladue HS, iLundberg IE. Izifo ezivuthayo zemisipha kunye nezinye i-myopathies. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, ii-eds. Incwadi kaKelley kunye neFirestein yeRheumatology. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; Ngo-2017: isahluko 85.