Umbhali: Gregory Harris
Umhla Wokudalwa: 14 Utshazimpuzi 2021
Hlaziya Umhla: 18 Eyenkanga 2024
Anonim
Mode of action of Saccharomyces boulardii CNCM I-745
Ividiyo: Mode of action of Saccharomyces boulardii CNCM I-745

Umxholo

ISaccharomyces boulardii ligwele. Yayifudula ichongwa njengendidi eyahlukileyo yegwele. Ngoku kukholelwa ukuba bubunzima beSaccharomyces cerevisiae. Kodwa i-Saccharomyces boulardii yahlukile kwezinye iintlobo ze-Saccharomyces cerevisiae eyaziwa ngokuba yi-brewer’s yeast kunye ne-baker’s yeast. I-Saccharomyces boulardii isetyenziswa njengeyeza.

I-Saccharomyces boulardii ixhaphake kakhulu ekunyangeni nasekuthinteleni isifo sohudo, kubandakanya iintlobo ezosulelayo ezinje ngesifo sorhudo i-rotaviral ebantwaneni. Inobungqina bokusetyenziswa kwezinye iintlobo zorhudo, amabala, kunye nosulelo lokugaya olunokukhokelela kwizilonda.

Isifo seCoronavirus 2019 (COVID-19): Akukho bungqina bokuba uxhase usebenzisa i-Saccharomyces boulardii ye-COVID-19. Landela ukhetho lokuphila olusempilweni kunye neendlela zothintelo eziqinisekisiweyo endaweni yoko.

Amayeza endalo aVimba weDatha Ukusebenza kwexabiso ngokusekwe kubungqina besayensi ngokwala manqanaba alandelayo: Ukusebenza, ukusebenza ngokukuko, okunokwenzeka ukuba kusebenze, okungenzeka kungasebenzi, kunokwenzeka ukungasebenzi, ukungasebenzi, kunye nobungqina obungonelanga bokulinganisa.

Ukulinganiswa kokusebenza kwe IIMPAHLA ZEBAKALA BOULARDII zezi zilandelayo:


Kusenokwenzeka ukuba iyasebenza ...

  • Urhudo. Uphando lubonisa ukuba ukunika iSaccharomyces boulardii kubantwana abanesifo sohudo kunokunciphisa ukuba ithatha ixesha elingakanani ukuya kuthi ga kusuku olunye. Kodwa iSaccharomyces boulardii ibonakala ingasebenzi kangako kunamayeza aqhelekileyo kurhudo, anje nge-loperamide (Imodium).
  • Urhudo olubangelwa yi-rotavirus. Ukunikezela nge-Saccharomyces boulardii kwiintsana kunye nabantwana abanesifo sorhudo esibangelwa yi-rotavirus kunokunciphisa ukuba isifo sohudo sihlala ixesha elingakanani ngosuku.

Inokwenzeka ukuba isebenze ...

  • Amabala. Uphando lubonisa ukuba ukuthatha iSaccharomyces boulardii ngomlomo kunceda ukuphucula ukubonakala kwamabala.
  • Urhudo kubantu abathatha amayeza okubulala iintsholongwane. Uninzi lophando lubonisa ukuba iSaccharomyces boulardii inokunceda ekuthinteleni isifo sohudo kubantu abadala nasebantwaneni abaphathwa ngamayeza okubulala iintsholongwane. Kwizigulana ezingama-9-13 ziphathwe ngeSaccharomyces boulardii ngexesha lokunyanga ngamayeza okubulala iintsholongwane, umntu omnye omncinci uya kuba nesifo sohudo esinxulumene namayeza.
  • Usulelo lwe-gastrointestinal tract yi-bacteria ebizwa ngokuba yiClostridium difficile. Ukuthatha iSaccharomyces boulardii kunye namayeza okubulala iintsholongwane kubonakala ngathi kunceda ukuthintela urhudo olunxulumene neClostridium difficile ekuphindweni kubantu abanembali yokuphindeka. Ukuthatha iSaccharomyces boulardii kunye namayeza okubulala iintsholongwane kubonakala ngathi kunceda ukuthintela iziqendu zokuqala zorhudo olunxulumene neClostridium difficile. Kodwa iingcali azikukhuthazi ukusebenzisa iSaccharomyces yokuthintela iziqendu zokuqala.
  • Usulelo lokugaya olunokukhokelela kwizilonda (Helicobacter pylori okanye H. pylori). Ukuthatha i-Saccharomyces boulardii ngomlomo kunye nonyango oluqhelekileyo H. pylori kuyanceda ukunyanga esi sifo. Malunga nabantu abali-12 kufuneka baphathwe nge-Saccharomyces boulardii eyongezelelweyo kwisigulana esinye ebesiya kuhlala sosulelekile ukuze sinyangeke. Ukuthatha i-Saccharomyces boulardii ikwanceda ukunqanda iziphumo ebezingalindelekanga ezinje ngesifo sorhudo kunye nesicaphucaphu esenzeka ngonyango oluqhelekileyo lwe-H. Pylori. Oku kunokunceda abantu bagqibe unyango lwabo oluqhelekileyo ku-H. Pylori.
  • Urhudo kubantu abane-HIV / AIDS. Ukuthatha i-Saccharomyces boulardii ngomlomo kubonakala ngathi kunciphisa urhudo olunxulumene ne-HIV.
  • Isifo esibi emathunjini kwiintsana ezingaphambi kwexesha (i-necrotizing enterocolitis okanye i-NEC). Uninzi lophando lubonisa ukuba ukunika iSaccharomyces boulardii ukukhawulezisa iintsana kuthintela i-NEC.
  • Urhudo lwabahambi. Ukuthatha i-Saccharomyces boulardii ngomlomo kubonakala kuthintela urhudo lwabahambi.

Kusenokwenzeka ukuba ayisebenzi ...

  • Usulelo lwegazi (sepsis). Uphando lubonisa ukuba ukunika iSaccharomyces boulardii ukukhawulezisa iintsana akuthinteli i-sepsis.

Akukho bungqina baneleyo bokulinganisa ukusebenza ...

  • Usulelo lwamathumbu olubangela urhudo (ikholera). I-Saccharomyces boulardii ibonakala ngathi ayiziphuculi iimpawu zekholera, nokuba inikwe unyango oluqhelekileyo.
  • Imemori kunye nezakhono zokucinga (umsebenzi wokuqonda). Uphando lwakwangoko lubonisa ukuba ukuthatha iSaccharomyces boulardii akuncedi abafundi benze ngcono kwiimviwo okanye kunciphise uxinzelelo.
  • Uhlobo lwesifo sokukrala kwamathumbu (isifo seCrohn). Ukuthatha iSaccharomyces boulardii kubonakala ngathi kunciphisa inani lokuhamba kwamathumbu kubantu abanesifo seCrohn. Uphando lwakwangoko lukwabonisa ukuba ukuthatha iSaccharomyces boulardii kunye ne-mesalamine kunokunceda abantu abanesifo seCrohn bahlale kuxolelo ixesha elide. Kodwa ukuthatha iSaccharomyces boulardii yodwa akubonakali kunceda abantu abanesifo seCrohn ukuba bahlale bexolelwe ixesha elide.
  • Icystic fibrosis. Uphando lwakwangoko lubonisa ukuba ukuthatha iSaccharomyces boulardii ngomlomo akulunciphisi usulelo lwegwele kwindawo yokugaya abantu abane-cystic fibrosis.
  • Ukumelwa yintliziyo. Uphando lwakwangoko lubonisa ukuba ukuthatha iSaccharomyces boulardii kunokuphucula ukusebenza kwentliziyo kubantu abanesifo sentliziyo.
  • Cholesterol ephezulu. Uphando lwakwangoko lubonisa ukuba iSaccharomyces boulardii kubonakala ngathi ayichaphazeli amanqanaba e-cholesterol.
  • Ingxaki yexesha elide yamathumbu amakhulu ebangela iintlungu zesisu (isifo esiswini esinokucaphuka okanye i-IBS). Uphando lubonisa ukuba ukuthatha iSaccharomyces boulardii kuphucula umgangatho wobomi kubantu abanesifo sorhudo-ubukhulu okanye uhlobo lwe-IBS. Kodwa i-Saccharomyces boulardii ayibonakali iphucula uninzi lweempawu ze-IBS ezinjengeentlungu zesisu, ukungxamiseka, okanye ukudumba.
  • Usulelo lwamathumbu ngama-parasites. Uphando lwakwangoko lubonisa ukuba ukuthatha iSaccharomyces boulardii ngomlomo kunye namayeza okubulala iintsholongwane kunciphisa urhudo kunye nentlungu esiswini kubantu abanesifo se-amoeba.
  • Ukuthungwa kwesikhumba kwiintsana (i-neundatal jaundice). Abanye abantwana bakhula i-jaundice emva kokuzalwa ngenxa yamanqanaba aphezulu e-bilirubin. Ukunika i-Saccharomyces boulardii kwiikota zeentsana kunokuthintela i-jaundice kunye nokunciphisa isidingo sonyango lwe-phototherapy kwinani elincinci lolu sana. Kodwa ayaziwa ukuba i-Saccharomyces boulardii inciphisa umngcipheko we-jaundice kwiintsana ezisemngciphekweni. Ukunika i-Saccharomyces boulardii kwiintsana kunye ne-phototherapy akwehlisi amanqanaba e-bilirubin ngcono kune-phototherapy yodwa.
  • Iintsana ezizalwe zinobunzima obungaphantsi kwama-2500 gram (iiponti ezi-5, ii-ounces eziyi-8). Ukunika isongezelelo seSaccharomyces boulardii emva kokuzalwa kubonakala kuphucula ukutyeba kunye nokondla kwiintsana ezizelwe ngaphambi kwexesha ezinobunzima bokuzalwa obuncinci.
  • Ukukhula okuthe kratya kwebhaktheriya kumathumbu amancinci. Uphando lwakwangoko lubonisa ukuba ukongeza i-Saccharomyces boulardii kunyango ngamayeza okubulala iintsholongwane kunciphisa ukukhula kweentsholongwane emathunjini ngcono kune-antibiotics yodwa.
  • Uhlobo lwesifo sokukrala kwamathumbu (ulcerative colitis). Uphando lwakwangoko lubonisa ukuba ukongeza i-Saccharomyces boulardii kunyango olusemgangathweni lwe-mesalamine kunokunciphisa iimpawu kubantu abane-ulcerative colitis ethambileyo.
  • Izilonda zenqanawa.
  • Fever blister.
  • Imihlathi.
  • Ukunganyamezelani kweLactose.
  • Isifo seLyme.
  • Ubuhlungu bemisipha obubangelwa kukuzilolonga.
  • Usulelo lwe-Urinary tract (UTIs).
  • Usulelo lwegwele.
  • Ezinye iimeko.
Ubungqina obungakumbi buyafuneka ukukala i-Saccharomyces boulardii kwezi zinto zisetyenziswayo.

ISaccharomyces boulardii ibizwa ngokuba yi "probiotic," into enobuhlobo enceda ukulwa izinto ezibangela izifo emathunjini afana neentsholongwane kunye negwele.

Xa kuthathwa ngomlomo: Saccharomyces boulardii yi NGOKUKHUSELEKILEYO kubantu abadala abaninzi xa bethathwe ngomlomo ukuya kuthi ga kwiinyanga ezili-15. Ingabangela igesi kwabanye abantu. Rhoqo, kunokubangela usulelo lomngundo olunokusasazeka ngokuhamba kwegazi kuye kuwo wonke umzimba (fungemia).

Amanyathelo okhuseleko kunye nezilumkiso:

Ukukhulelwa kunye nokuncancisa: Akukho lwazi lwaneleyo lwanokuthenjwa lokwazi ukuba ngaba iSaccharomyces boulardii ikhuselekile ukusetyenziswa xa ukhulelwe okanye uncancisa. Hlala kwicala elikhuselekileyo kwaye uphephe ukusetyenziswa.

Abantwana: Saccharomyces boulardii yi UKHUSELEKO OLUNOKWENZEKA kubantwana xa bethathwe ngomlomo ngokufanelekileyo. Nangona kunjalo, urhudo ebantwaneni kufuneka kuvavanywe yingcali yezempilo ngaphambi kokusebenzisa iSaccharomyces boulardii.

Abantu abadala: Abantu abadala banokuba nomngcipheko owandayo wosulelo lokungunda xa uthatha iSaccharomyces boulardii. Hlala kwicala elikhuselekileyo kwaye uphephe ukusetyenziswa.

Amandla omzimba abuthathaka: Kukho inkxalabo yokuba ukuthatha iSaccharomyces boulardii kunokubangela i-fungemia, leyo bubukho begwele egazini. Elona nani lamatyala eSchcharomyces boulardii enxulumene nefungemia kunzima ukufumanisa. Nangona kunjalo, umngcipheko ubonakala ungowona mkhulu kubantu abagula kakhulu okanye abaye benza buthathaka amajoni omzimba. Ngokukodwa, abantu abane-catheters, abo bafumana ityhubhu yokondla, kunye nabo baphathwa ngamayeza amaninzi okanye ii-antibiotics ezisebenza kwiintlobo ezahlukeneyo zosulelo babonakala besemngciphekweni omkhulu. Kwiimeko ezininzi, i-fungemia ibangelwe kukungcoliseka kwe-catheter yomoya, umphezulu wendalo, okanye izandla ezingcoliswe yi-Saccharomyces boulardii.

Igwele lokungezwani komzimba: Abantu abanegwele lokungezwani komzimba banokungabikho komzimba kwiimveliso eziqukethe iSaccharomyces boulardii, kwaye bayacetyiswa ukuba baziphephe ezi mveliso.

Incinci
Jonga olu dibaniso.
Amayeza osulelo lokungunda (iAntifungals)
ISaccharomyces boulardii yfungus. Amayeza osulelo lokungunda anceda ukunciphisa ukungunda emzimbeni nasemzimbeni. Ukuthatha i-Saccharomyces boulardii ngamayeza osulelo lokungunda kunokunciphisa ukusebenza kweSaccharomyces boulardii.
Amanye amayeza osulelo lokungunda aquka i-fluconazole (Diflucan), icaspofungin (Cancidas), itraconazole (Sporanox) amphotericin (Ambisome), kunye nezinye.
Akukho kunxibelelana kwaziwayo kunye namayeza kunye nezongezo.
Akukho kunxibelelana kwaziwayo nokutya.
La machiza alandelayo afundwe kuphando lwezesayensi:

ABADALA

NGOMLOMO:
  • Ukuhanjiswa kwesisu kubantu abathatha ii-antibiotics (isifo sohudo esinxulumene ne-antibiotic)I-250-500 mg ye-Saccharomyces boulardii ithathwa amaxesha ama-2-4 imihla ngemihla ukuya kuthi ga kwiiveki ezi-2 ixhaphake kakhulu. Kwiimeko ezininzi, idosi yemihla ngemihla ayidluli kwi-1000 mg yonke imihla.
  • Usulelo lwephecana lesisu ngamabhaktheriya abizwa ngokuba yiClostridium difficileUkuthintela ukuphindaphinda, i-500 mg ye-Saccharomyces boulardii kabini yonke imihla kwiiveki ezi-4 kunye nonyango lwe-antibiotics lusetyenzisiwe.
  • Ukusuleleka kwintsholongwane engakhokelela kwizilonda (Helicobacter pylori okanye H. pylori): 500-1000 mg yeSaccharomyces boulardii yonke imihla kangangeeveki ezi-1-4 isetyenziswa kakhulu.
  • Urhudo kubantu abane-HIV / AIDS: Iigrama ezi-3 zeSaccharomyces boulardii mihla le.
  • Urhudo lwabahambi: 250-1000 mg ye-Saccharomyces boulardii mihla le kwinyanga e-1.
ABANTWANA

NGOMLOMO:
  • Ukuhanjiswa kwesisu kubantu abathatha ii-antibiotics (isifo sohudo esinxulumene ne-antibiotic)I-250 mg ye-Saccharomyces boulardii kube kanye okanye kabini ngemini ixesha lokusetyenziswa kwee-antibiotics.
  • YorhudoUkunyanga isifo sohudo, i-250 mg ye-Saccharomyces boulardii kube kanye okanye kabini yonke imihla okanye i-10 yezigidigidi zokwenza iikholoni kanye yonke imihla kangangeentsuku ezintlanu. Ukunyanga urhudo oluqhubekekayo, i-1750 yezigidigidi ukuya kwi-175 yezigidi zezigidi zeekoloni zokwenza i-Saccharomyces boulardii kabini yonke imihla kwiintsuku ezintlanu kuye kwasetyenziswa. Ukuthintela urhudo kubantu abafumana ukutya okwe-tube, i-500 mg ye-Saccharomyces boulardii isetyenziswe amaxesha amane mihla le.
  • Isifo sohudo esibangelwa yi-rotavirusKusetyenziswe i-200-250 mg ye-Saccharomyces boulardii kabini imihla ngemihla kwiintsuku ezi-5.
  • Kwisifo esibi samathumbu kwiintsana ezingaphambi kwexesha (i-necrotizing enterocolitis okanye i-NEC): 100-200 mg / kg Saccharomyces boulardii yonke imihla, ukuqala kwiveki yokuqala emva kokuzalwa.
Iprobiotic, iProbiotique, iSaccharomyces, iSaccharomyces Boulardii CNCM I-745, iSaccharomyces Boulardii HANSEN CBS 5926, Saccharomyces Boulardii Lyo CNCM I-745, Saccharomyces Boulardius, Saccharomyces Cerevisiae Boulardii, Sacchomyomy Caseschomyosia) ICerevisiae HANSEN CBS 5926, Saccharomyces cerevisiae var boulardii, S. Boulardii, SCB.

Ukuze ufunde okungakumbi malunga nokubhalwa kweli nqaku, nceda ubone Amayeza endalo aVimba weDatha indlela yokusebenza.


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