Umbhali: Marcus Baldwin
Umhla Wokudalwa: 21 Isilimela 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
OPIOID AGONIST-ANTAGONIST | pentazocine | Buprenorphine | partial agonist
Ividiyo: OPIOID AGONIST-ANTAGONIST | pentazocine | Buprenorphine | partial agonist

Umxholo

I-Pentazocine inokuba ngumkhwa wokwenza, ngakumbi ngokusetyenziswa kwexesha elide. Thatha ipentazocine ngokuchanekileyo njengoko kuyalelwe. Sukuyithatha ngaphezulu, yithathe rhoqo, okanye uthathe ngendlela eyahlukileyo kunokuba uyalelwe ngugqirha. Ngelixa uthatha i-pentazocine, xoxa kunye nomboneleli wakho wokhathalelo lwempilo iinjongo zakho zonyango lweentlungu, ubude bonyango, kunye nezinye iindlela zokulawula iintlungu zakho. Tshela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho usela utywala okanye wakha wasela izixa ezikhulu zotywala, wasebenzisa okanye wakha wasebenzisa iziyobisi ezitalatweni, okanye wasebenzisa kakhulu amayeza kagqirha, okanye wagqithisa, okanye wakha wanengxaki yoxinzelelo okanye esinye isifo sengqondo. Kukho umngcipheko omkhulu wokuba uyisebenzise kakhulu ipentazocine ukuba unayo okanye wakhe wanayo nalemiqathango. Thetha nomboneleli wakho wezempilo ngokukhawuleza kwaye ucele isikhokelo ukuba ucinga ukuba une-opioid okanye ungatsalela umnxeba i-U.S. Iziyobisi kunye noLawulo lweeNkonzo zeMpilo yeNgqondo (SAMHSA) kwiNombolo yoNcedo yeSizwe e-1-800-662-HELP.

I-Pentazocine inokubangela iingxaki zokuphefumla ezinzulu okanye ezisongela ubomi, ngakumbi kwiiyure zokuqala ezingama-24 ukuya kwezingama-72 zonyango lwakho nangaliphi na ixesha elonyukayo. Ugqirha wakho uya kukujonga ngononophelo ngexesha lonyango lwakho. Tshela ugqirha wakho ukuba ukhe wakha wanciphisa ukuphefumla okanye isifuba. Ugqirha wakho uya kukuxelela ukuba ungathathi ipentazocine. Xelela ugqirha wakho ukuba ukhe okanye unesifo semiphunga esifana nesifo esinganyangekiyo semiphunga (COPD; iqela lezifo ezichaphazela imiphunga kunye neendlela zomoya), ukwenzakala entloko, ithumba lobuchopho, okanye nayiphi na imeko eyonyusa inani uxinzelelo kwingqondo yakho. Umngcipheko wokuba ube neengxaki zokuphefumla unokuba ngaphezulu ukuba umdala okanye ubuthathaka okanye ungondleki ngenxa yesifo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango lonyango: ukuphefumla okucothayo, ikhefu elide phakathi kokuphefumla, okanye ukuphefumla kancinci.


Ukuthatha amayeza athile nge-pentazocine kunokunyusa umngcipheko wokuba ube neengxaki zokuphefumla ezinzulu okanye ezisongela ubomi, i-sedation, okanye i-coma. Xelela ugqirha wakho kunye nosokhemesti ukuba uthatha okanye uceba ukuthatha nawaphi na amayeza alandelayo: amayeza athile okubulala iintsholongwane kubandakanya itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), kunye nevoriconazole (Vfend); benzodiazepines ezifana ne-alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), kunye ne triaz carbamazepine (Carbatrol, Epitol, Tegretol, Teril); i-clarithromycin (i-Biaxin, kwi-PrevPac); i-erythromycin (i-Erytab, i-Erythrocin); amayeza athile kwintsholongwane ye-immunodeficiency virus (HIV) kubandakanya indinavir (Crixivan), nelfinavir (Viracept), kunye ne-ritonavir (Norvir, e-Kaletra); amayeza okugula ngengqondo, isicaphucaphu, okanye iintlungu; izihlunu ezonwabisayo; phenytoin (iDilantin, iPhenytek); irifampin (Rifadin, Rimactane, eRifamate); ukuthomalalisa; iipilisi zokulala; okanye izinto ezizolisayo. Ugqirha wakho unokufuna ukutshintsha amayeza akho kwaye uza kukujonga ngononophelo. Ukuba uthatha i-pentazocine ngalo naliphi na kula mayeza kwaye uvelisa ezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo: isiyezi esingaqhelekanga, intloko ebuthongweni, ukulala kakhulu, ukucothisa okanye ukuphefumla nzima, okanye ukungaphenduli. Qiniseka ukuba umnakekeli wakho okanye amalungu osapho ayazi ukuba zeziphi iimpawu ezinokubanzima ukuze babize ugqirha okanye ukhathalelo lonyango olungxamisekileyo ukuba awukwazi ukuzifunela unyango wedwa.


Ukusela utywala, ukuthatha amayeza kagqirha okanye ongabhalisiyo aqukethe utywala, okanye ukusebenzisa iziyobisi ezitalatweni ngexesha lonyango nge-pentazocine kwandisa umngcipheko wokuba uza kuba neziphumo ebezingalindelekanga. Musa ukusela utywala, thatha amayeza kagqirha okanye ongabhalisiyo aqukethe utywala, okanye usebenzise iziyobisi zasesitalatweni ngexesha lonyango lwakho.

Musa ukuvumela nabani na ongomnye ukuba athathe amayeza akho. IPentazocine inokulimaza okanye ibangele ukufa kwabanye abantu abathatha amayeza akho, ngakumbi abantwana.

Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba uthatha ipentazocine rhoqo ngexesha lokukhulelwa kwakho, umntwana wakho unokuba neempawu ezisongela ubomi emva kokuzalwa. Xelela ugqirha wosana lwakho ngoko nangoko ukuba umntwana wakho unazo naziphi na kwezi mpawu zilandelayo: ukucaphuka, ukuxhalaba, ukulala ngendlela engaqhelekanga, ukukhala okuphezulu, ukungcangcazela okungalawulekiyo kwenxalenye yomzimba, ukugabha, urhudo, okanye ukusilela ukutyeba.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango lwakho nge-pentazocine kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.


Thetha nogqirha wakho malunga neengozi zokuthatha ipentazocine.

I-Pentazocine isetyenziselwa ukunciphisa iintlungu ezibukhali. I-Pentazocine ikwiklasi yamayeza abizwa ngokuba yi-opiate (narcotic) analgesics. Isebenza ngokutshintsha indlela ingqondo kunye nenkqubo yovalo ephendula ngayo kwintlungu.

IPentazocine iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa qho kwiiyure ezi-3 ukuya kwezi-4 xa kufuneka njalo. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ipentazocine ngokuchanekileyo njengoko kuyalelwe.

Iipilisi zePentazocine kufuneka zithathwe ngomlomo. Ungazami ukunyibilika kunye nokujova iipilisi. Ukujova ipentazocine kunokubangela iingxaki zempilo okanye ukufa. I-Naloxone yongezwa kwiipilisi ukuze abantu abafake iipilisi ezichithakeleyo bangayi kuba nefuthe le-pentazocine.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ipentazocine,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-pentazocine, naloxone, nawaphi na amanye amayeza, okanye naziphi na izithako kwiipilisi zepentazocine. Buza ugqirha wakho okanye usokhemesti uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amayeza entloko njenge-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Alsuma, Imitrex, eTreximet), kunye ne-zolmitriptan (iZomig); amayeza ukukhwehlela, ukubanda, okanye i-aleji; I-5HT3 i-serotonin blockers efana ne-alosetron (Lotronex), i-dolasetron (i-Anzemet), i-granisetron (i-Kytril), i-ondansetron (i-Zofran, i-Zuplenz), okanye i-palonosetron (i-Aloxi); i-inhibitors ekhethiweyo ye-serotonin-reuptake inhibitors enjenge citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), kunye sertraline (Zoloft); i-serotonin kunye ne-norepinephrine reuptake inhibitors enje nge-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), milnacipran (Savella), kunye ne-venlafaxine (Effexor); i-tramadol; Itrazodone (Oleptro); kunye ne-tricyclic antidepressants (’mood elevators’) ezinje ngeamitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactiline), kunye neTrimipramine. Xelela ugqirha wakho okanye usokhemesti ukuba uthatha okanye ufumana naliphi na kula mayeza alandelayo okanye uyekile ukuwathatha kwezi veki zimbini zidlulileyo: i-monoamine oxidase (MAO) inhibitors efana ne-isocarboxazid (Marplan), linezolid (Zyvox), methylene luhlaza, phenelzine (Nardil), rasagiline (Azilect), selegiline (Emsam, Eldepryl, Zelapar), kunye ne-tranylcypromine (iParnate). Uninzi lwamanye amayeza anokusebenzisana nepentazocine, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
  • xelela ugqirha wakho ukuba ukhe wanengxaki ekuchameni; ukuphazamiseka kokuthimba; imiphunga, isibindi, izintso, idlala lengqula, inyongo, okanye isifo sentliziyo.
  • xelela ugqirha wakho ukuba uncelisa.
  • Kuya kufuneka uyazi ukuba eli yeza linciphisa ukuchuma emadodeni nakwabasetyhini. Thetha nogqirha wakho malunga nemingcipheko yokuthatha ipentazocine.
  • thetha nogqirha wakho malunga nokusetyenziswa okukhuselekileyo kwala mayeza ukuba uneminyaka engama-65 ubudala okanye ngaphezulu. Abantu abadala abadala akufuneki bathathe ipentazocine kuba ayikhuselekanga njengamanye amayeza anokusetyenziselwa ukunyanga imeko efanayo.
  • ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha ipentazocine.
  • Kuya kufuneka uyazi ukuba eli yeza linokukwenza wozele. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

La mayeza ahlala ethathwa njengoko kufuneka. Ukuba ugqirha wakho ukuxelele ukuba uthathe ipentazocine rhoqo, thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

IPentazocine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ndiziva ndidiniwe kakhulu
  • intloko elula
  • ukozela
  • utshintsho lweemvakalelo
  • intloko ebuhlungu
  • isisu esimoshakele
  • ukuqhina
  • isisu esibuhlungu
  • irhashalala
  • ubunzima bokuchama

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko:

  • ubunzima bokuphefumla
  • utshintsho kwintliziyo
  • Ukuphazamiseka, ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angekhoyo), umkhuhlane, ukubila, ukudideka, ukubetha kwentliziyo okukhawulezayo, ukungcangcazela, ukuqina kwemisipha okanye ukujijeka, ukulahleka kokulungelelaniswa, isicaphucaphu, ukugabha okanye urhudo
  • isicaphucaphu, ukugabha, ukungabi namdla wokutya, ukuba buthathaka okanye isiyezi
  • ukungakwazi ukufumana okanye ukugcina ulwakhiwo
  • ukuya exesheni ngokungaqhelekanga
  • ukunciphisa umnqweno wesondo
  • isiqaqa

IPentazocine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Ngelixa uthatha ipentazocine, kuya kufuneka uthethe nogqirha wakho malunga neyeza lokuhlangula elibizwa ngokuba yi-naloxone ngokulula (umzekelo, ikhaya, iofisi). I-Naloxone isetyenziselwa ukuguqula iziphumo ezisongela ubomi kwi-overdose. Isebenza ngokuthintela iziphumo ze-opiates ukunciphisa iimpawu ezinobungozi ezibangelwa ngamanqanaba aphezulu ee-opiates egazini. Ugqirha wakho unokukuyalela i-naloxone ukuba uhlala kwikhaya apho kukho abantwana abancinci okanye umntu osebenzise gwenxa isitalato okanye amayeza amiselweyo. Kuya kufuneka uqiniseke ukuba wena kunye namalungu osapho lwakho, abakhathaleli, okanye abantu abachitha ixesha kunye nawe bayayazi indlela yokwazi ukuba libanda, indlela yokusebenzisa naloxone, kunye nento onokuyenza de kufike uncedo lwezonyango olungxamisekileyo. Ugqirha wakho okanye usokhemesti uza kukubonisa kunye namalungu osapho lwakho ukuba ulisebenzisa njani eliyeza. Buza usokhemesti wakho ngemiyalelo okanye undwendwele iwebhusayithi yomenzi ukuze ufumane imiyalelo. Ukuba iimpawu zokudlula ngaphezulu zenzeka, umhlobo okanye ilungu losapho kufuneka linike idosi yokuqala ye-naloxone, fowunela i-911 kwangoko, kwaye uhlale nawe kwaye ujonge kufutshane kude kufike uncedo lwezonyango olungxamisekileyo. Iimpawu zakho zinokubuya emva kwemizuzu embalwa emva kokuba ufumane i-naloxone. Ukuba iimpawu zakho zibuya, umntu lowo kufuneka akunike enye idosi ye-naloxone. Amanqanaba ongezelelweyo anokunikwa yonke imizuzu emi-2 ukuya kwemi-3, ukuba iimpawu ziyabuya ngaphambi kokuba uncedo lonyango lufike.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

  • ukuphefumla kancinci okanye kancinci
  • ubunzima bokuphefumla
  • ukulala kakhulu
  • andikwazi kuphendula okanye ukuvuka

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-pentazocine.

Ngaphambi kokuba uvavanywe elebhu (ngakumbi ezo zibandakanya imethylene eluhlaza okwesibhakabhaka), xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba uthatha ipentazocine.

Musa ukuvumela nabani na ukuba athathe amayeza akho. IPentazocine yinto elawulwayo. Imigqaliselo inokugcwaliswa kuphela linani eliqingqiweyo lamaxesha; buza usokhemesti wakho ukuba unayo nayiphi na imibuzo.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • UTalwin® NX
  • UTalacen® (njengemveliso yokudibanisa equlathe iAcetaminophen, iPentazocine)

Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.

Ukuhlaziywa kokugqibela-02/15/2021

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