Inaliti ye-Etanercept

Umxholo

• Ngaphambi kokusebenzisa inaliti yokufumana inaliti,
• I-Etanercept inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga okanye ezo zikhankanyiweyo KWICANDELO LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane uncedo lonyango olungxamisekileyo:

Ukusebenzisa i-etanercept injection kunokunciphisa amandla akho okulwa nokusuleleka kunye nokwandisa umngcipheko wokufumana usulelo olunzulu, kubandakanywa neentsholongwane ezinobungozi, ibhaktheriya, okanye ukusuleleka kwintsholongwane esasazeka kuwo wonke umzimba. Ezi zifo zingafuna ukunyangwa esibhedlele kwaye zingabangela ukufa. Tshela ugqirha wakho ukuba uhlala ufumana naluphi na uhlobo losulelo okanye ukuba ucinga ukuba unalo naluphi na uhlobo losulelo ngoku. Oku kubandakanya usulelo oluncinci (njengokusikwa okuvulekileyo okanye izilonda), usulelo olufikayo (olufana nezilonda ezibandayo) kunye nosulelo olungapheliyo olungapheliyo. Xelela ugqirha wakho ukuba ukhe unesifo seswekile, intsholongwane kaGawulayo (i-HIV), ufumene isifo se-immunodeficiency syndrome (i-AIDS), okanye nayiphi na imeko echaphazela amajoni akho omzimba. Kuya kufuneka uxelele ugqirha wakho ukuba uhlala okanye wakha waphila kwiindawo ezifana ne-Ohio ne-Mississippi river valleys apho kukho izifo zokungunda ezixhaphakileyo. Buza ugqirha wakho ukuba awazi ukuba ngaba ezi zifo zixhaphakile kwindawo yakho. Xelela ugqirha wakho ukuba uthatha amayeza anciphisa ukusebenza kwamajoni omzimba afana nala alandelayo: abatacept (Orencia); anakinra (iKineret); i-azathioprine (Imuran); i-steroids kubandakanya i-dexamethasone, i-methylprednisolone (Medrol), i-prednisolone (i-Prelone) kunye ne-prednisone; okanye i-methotrexate (Rheumatrex).

Ugqirha wakho uya kukujonga esosulelweni ngexesha nasemva konyango lwakho. Ukuba unazo naziphi na kwezi mpawu zilandelayo ngaphambi kokuba uqale unyango lwakho okanye ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha okanye emva nje konyango lwakho, tsalela umnxeba kwangoko kugqirha: ubuthathaka; ukubila; ubunzima bokuphefumla; umqala obuhkungu; ukukhohlela; ukukhohlela umchamo wegazi; ifiva; ukuhla ukusinda; ukudinwa kakhulu; urhudo; isisu esibuhlungu; iimpawu ezifana nomkhuhlane; ulusu olufudumeleyo, olubomvu, okanye olubuhlungu; okanye ezinye iimpawu zosulelo.

Unokosulelwa sisifo sephepha (i-TB, uhlobo losulelo lwemiphunga) okanye i-hepatitis B (uhlobo lwesifo sesibindi) kodwa ungenazimpawu zesi sifo. Kule meko, i-etanercept injection inokunyusa umngcipheko wokuba usulelo lwakho luya kuba lubi kakhulu kwaye uya kuphuhlisa iimpawu. Ugqirha wakho uza kwenza uvavanyo lolusu ukuze abone ukuba unesifo se-TB esingasebenziyo kwaye angayalela ukuba kwenziwe uvavanyo lwegazi ukuze abone ukuba unesifo se-hepatitis B esingasebenziyo. Ukuba kukho imfuneko, ugqirha wakho uya kukunika amayeza ukunyanga olu sulelo ngaphambi kokuba uqale ngenaliti ye-etanercept. Xelela ugqirha wakho ukuba ukhe wakha okanye wakha wanayo na i-TB, ukuba ngaba wakhe wahlala kwilizwe apho ixhaphake kakhulu i-TB, okanye ukuba ukhe wakufutshane nomntu one-TB. Ukuba unazo naziphi na kwezi mpawu zilandelayo ze-TB, okanye ukuba uvela kwezi mpawu ngexesha lonyango lwakho, tsalela umnxeba kwangoko: ukukhohlela, ukwehla kobunzima, ukulahleka kwethoni yezihlunu, okanye umkhuhlane. Biza ugqirha wakho ngokukhawuleza ukuba unayo nayiphi na le mpawu yesifo sokudumba kwesibindi kohlobo B okanye ukuba ukhula kwezi mpawu ngexesha okanye emva konyango lwakho: ukudinwa kakhulu, ukuba tyheli kolusu okanye amehlo, ukungabi namdla, isicaphucaphu okanye ukugabha, iintlungu zemisipha, umchamo omnyama, intshukumo yombala wodongwe, umkhuhlane, ukugodola, iintlungu zesisu, okanye irhashalala.

Abanye abantwana kunye nolutsha abafumene inaliti yokufumana i-etanercept kunye namayeza afanayo bakhulisa umhlaza onobungozi okanye osongela ubomi kubandakanya i-lymphoma (umhlaza oqala kwiiseli ezilwa nosulelo). Ukuba umntwana wakho uvela kwezi mpawu ngexesha lonyango, biza ugqirha ngokukhawuleza: ukuncipha kobunzima obungachazwanga; amadlala adumbayo entanyeni, phantsi kwempuphu, okanye kumphimbo; okanye ukugruzuka okulula okanye ukopha. Thetha nogqirha womntwana wakho malunga neengozi zokufaka inaliti ye-etanercept kumntwana wakho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-etanercept kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokusebenzisa i-etanercept injection.

I-Etanercept isetyenziselwa yodwa okanye namanye amayeza ukukhulula iimpawu ezithile zokuphazamiseka komzimba (iimeko apho amajoni omzimba ahlasela amalungu asempilweni kwaye abangela iintlungu, ukudumba kunye nomonakalo) kubandakanya:

• isifo samathambo (imeko apho umzimba uhlasela amalungu ayo, ubangela iintlungu, ukudumba, kunye nokuphulukana nomsebenzi) kubantu abadala,
• i-psoriatic arthritis (imeko ebangela iintlungu ezidibeneyo kunye nokudumba kunye nezikali kulusu) kubantu abadala,
• i-juvenile idiopathic arthritis (JIA; imeko echaphazela abantwana apho umzimba uhlasela amalungu ayo, ubangela iintlungu, ukudumba, ukuphulukana nomsebenzi, kunye nokulibaziseka kokukhula kunye nophuhliso) kubantwana abaneminyaka emi-2 ubudala nangaphezulu,
• i-ankylosing spondylitis (imeko apho umzimba uhlasela amalungu omqolo kunye nezinye iindawo ezibangela iintlungu kunye nomonakalo odibeneyo),
• I-plaque psoriasis engapheliyo (isifo solusu apho umbala obomvu, onamaxolo ubonakala kwezinye iindawo zomzimba) kubantu abadala nakubantwana abaneminyaka emi-4 ubudala nangaphezulu abane-psoriasis enzima kakhulu ukuba inyangwe ngamayeza ezinto kuphela.

I-Etanercept ikudidi lwamayeza abizwa ngokuba yi-tumor-necrosis factor (TNF) inhibitors. Isebenza ngokuthintela isenzo se-TNF, into esemzimbeni ebangela ukudumba

Inaliti ye-Etanercept iza njengesisombululo (ulwelo) kwisirinji ekhethiweyo kunye nesixhobo sokuzenzekelayo, kunye nanjengompu oxutywe nolwelo olunikiweyo. I-Etanercept itofelwe ngaphantsi (phantsi kwesikhumba). Ihlala itofwe kanye ngeveki. Xa i-etanercept injection isetyenziselwa ukunyanga i-plaque psoriasis engapheliyo, inokujova kabini ngeveki kwiinyanga zokuqala ze-3 zonyango kwaye kanye ngeveki emva kweenyanga ezintathu zokuqala. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-etanercept ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Uya kufumana idosi yakho yokuqala yenaliti ye-etanercept kwiofisi kagqirha. Emva koko, unokulifaka ngokwakho iyeza ekhaya okanye umhlobo okanye isihlobo senze inaliti. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kwenza inaliti indlela yokujova i-etanercept. Funda imiyalelo ebhaliweyo eza ne-etanercept injection ngaphambi kokuba utofe iyeza.

Iibhola ze-etanercept injection inokuqulatha amayeza aneleyo ngaphezulu kwethamo elinye. Ukuba kukho iyeza elaneleyo elisele kwi-vial yedosi epheleleyo, beka ibhotile kwifriji ngokukhawuleza okukhulu, kodwa kungadlulanga iiyure ezi-4 emva kokuba uyixube. Ungayigcina ingqayi yenaliti ye-etanercept ukuya kuthi ga kwiintsuku ezili-14 emva kokuba uyixube ukuba kukho iyeza elaneleyo elisele idosi epheleleyo. Nangona kunjalo, akufuneki udibanise imixholo yeebhotile ezimbini okanye nangaphezulu zenaliti ye-etanercept ukwenza idosi epheleleyo. Kuya kufuneka ungadibanisi amanye amayeza ngenaliti ye-etanercept.

Ukuba amayeza akho angena kwisirinji ekhethiweyo okanye isixhobo sokuzenzekelayo, sebenzisa isirinji nganye okanye isixhobo kube kanye kwaye ufake isisombululo kwisirinji okanye isixhobo. Nokuba kusekho isisombululo esisele kwisirinji okanye isixhobo, musa ukusisebenzisa kwakhona. Lahla iinaliti ezisetyenzisiweyo, iisirinji kunye nezixhobo kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Ukuba usebenzisa isirinji ekhethiweyo, isixhobo sokufaka inaliti, okanye igutyana efrijiweyo, beka isirinji, isixhobo, okanye igutyana kwindawo ethe tyaba kwaye uyivumele ifudumele kubushushu begumbi kangangemizuzu eyi-15 ukuya kwengama-30 ngaphambi kokuba ulungele itofa iyeza. Sukuzama ukufudumeza amayeza ngokuwutshisa kwimicrowave, ngokuwabeka emanzini ashushu, okanye ngayo nayiphi na enye indlela.

Musa ukushukumisa isirinji, isixhobo sokuzenzekelayo, okanye igutyana eliqukethe i-etanercept. Lumka ungasilahli isixhobo kwindawo enzima kuba oko kunokonakalisa isixhobo, isirinji okanye inaliti.

Ngalo lonke ixesha jonga kwisisombululo se-etanercept ngaphambi kokuyifaka. Jonga ukuba umhla wokuphelelwa awukadluli, kwaye ulwelo lucacile kwaye alunambala. Umbane unokuqulatha amasuntswana amhlophe amhlophe, kodwa akufuneki abenamasuntswana amakhulu okanye anemibala. Sukusebenzisa isirinji okanye ipeni yedosi ukuba iqhekeziwe okanye yaphukile, ukuba iphelelwe lixesha, okanye ukuba ulwelo lunamafu okanye luqulathe amasuntswana amakhulu okanye anemibala.

Indawo efanelekileyo yokutofa inaliti ye-etanercept iphambili kumathanga akho aphakathi. Ungalifaka iyeza kwisisu sakho esisezantsi ngaphantsi kwenkaba yakho, ngaphandle kwendawo ezii-intshi ezi-5 (iisentimitha ezi-5) ejikeleze inkaba yakho. Ukuba kukho umntu okufaka inaliti, loo mntu unokufaka iyeza engalweni yakho ephezulu. Ukuba i-etanercept itofelwe kwiingalo ezingaphezulu okanye esiswini, ulusu kuloo ndawo kufuneka yolulwe ukuze yenze indawo eqinileyo yenaliti. Khetha indawo eyahlukileyo yenaliti nganye. Sukujova kwindawo apho ulusu luthambile, lonzakele, lubomvu, lukhuni, okanye apho kukho amanxeba okanye amanqaku olulekileyo. Ukuba une-psoriasis, musa ukujova kulusu olubomvu, elingqindilili, oluphakanyisiweyo, okanye olunamaxolo.

Inaliti ye-Etanercept inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Qhubeka nokusebenzisa inaliti ye-etanercept nokuba uziva uphilile. Sukuyeka ukusebenzisa i-etanercept ngaphandle kokuthetha nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yokufumana inaliti,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-etanercept okanye nawaphi na amanye amayeza. Ukuba uza kusebenzisa isirinji ekhethiweyo okanye isixhobo sokufaka inaliti esizenzekelayo, xelela ugqirha wakho ukuba wena okanye umntu oza kukufaka inaliti iyeza lakho aleji kwirabha okanye kwilatex.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ngokukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO, amayeza eswekile, kunye ne-cyclophosphamide (ICytoxan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe waxhuzula okanye wakha waxhuzula; isifo esichaphazela inkqubo yakho yeemvakalelo, enjenge-multiple sclerosis (MS; ukuphulukana nolungelelwaniso, ubuthathaka, kunye nokuba ndindisholo ngenxa yomonakalo wemithambo-luvo); i-myelitis enqamlezileyo (ukudumba kwethambo lomqolo okunokubangela ukungaqhelekanga, ukulahleka kwemvakalelo, okanye ukuphulukana namandla okuhambisa umzimba ongezantsi); i-optic neuritis (ukudumba kwemithambo-luvo ethumela imiyalezo ukusuka kwiliso ukuya kwingqondo); iingxaki zokopha; isifo sesibindi, okanye ukusilela kwentliziyo.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa usebenzisa i-etanercept, biza ugqirha wakho. Ukuba usebenzisa i-etanercept injection ngexesha lokukhulelwa kwakho, qiniseka ukuba uthethe nogqirha womntwana wakho malunga noku emva kokuba umntwana wakho ezelwe. Umntwana wakho kusenokufuneka afumane ugonyo oluthile kamva kunesiqhelo.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-etanercept.
• awunalo ugonyo ngexesha lonyango lwakho nge-etanercept ngaphandle kokuthetha nogqirha wakho. Ukuba umntwana wakho uya kunyangwa ngenaliti ye-etanercept, thetha nogqirha wakhe malunga nokugonywa ekufuneka kunikwe ngaphambi kokuqala konyango. Ukuba kunokwenzeka, umntwana wakho kufuneka anikwe lonke ugonyo olufunekayo kubantwana abakwiminyaka yobudala bakhe ngaphambi kokuqala unyango.
• ukuba ufumene inkukhu xa usebenzisa i-etanercept, biza ugqirha wakho ngokukhawuleza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Faka isitofu esilahlekileyo ngokukhawuleza nje emva kokuba usikhumbule. Ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukujoba idosi ephindwe kabini ukulungiselela eyilahlekileyo.

I-Etanercept inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubomvu, ukurhawuzelela, iintlungu, okanye ukudumba kwindawo yenaliti
• intloko ebuhlungu
• isicaphucaphu
• ukugabha
• isilungulela
• isisu esibuhlungu
• ubuthathaka
• ukukhohlela

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na iziphumo ebezingalindelekanga okanye ezo zikhankanyiweyo KWICANDELO LESILUMKISO ESIBALULEKILEYO, tsalela ugqirha ngokukhawuleza okanye ufumane uncedo lonyango olungxamisekileyo:

• ukuxhuzula
• ukugruzuka
• ukopha
• ulusu oluthuthu
• isikhumba esidumbileyo
• irhashalala
• urhwebo
• ukurhawuzelela
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ubunzima bokuphefumla okanye ukugwinya
• irhashalala ebusweni neengalo eziba mandundu elangeni
• ukuba ndindisholo okanye ukurhawuzelela
• iingxaki zombono
• ubuthathaka kwiingalo okanye emilenzeni
• isiyezi
• bomvu, amabala anamaxolo okanye amaqhuma agcwele ulusu kulusu

Abantu abadala abafumana inaliti ye-etanercept mhlawumbi basemngciphekweni omkhulu wokukhula kwe-lymphoma, leukemia (umhlaza oqala kwiiseli ezimhlophe zegazi), umhlaza wolusu, kunye nezinye iintlobo zomhlaza kunabantu abadala abangafumani le nyango. Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-etanercept.

Inaliti ye-Etanercept inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina i-etanercept injection kwifriji kodwa ungagcini. Gcina iibhotile, iisirinji ezizalisiweyo, okanye izixhobo zokufaka inaliti kwiibhokisi zazo zokuqala ukuzikhusela ekukhanyeni. Ukuba uxube ibhotile ye-etanercept powder kunye nolwelo olunikiweyo, unokugcina isisombululo kwifriji kangangeentsuku ezili-14.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-etanercept.

Ngaphambi kokuba uvavanywe elebhu, xelela ugqirha wakho kunye nabasebenzi baselebhu ukuba usebenzisa i-etanercept.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ungenelelo^®