Umbhali: Marcus Baldwin
Umhla Wokudalwa: 16 Isilimela 2021
Hlaziya Umhla: 19 Eyenkanga 2024
Anonim
No benefit for adjuvant ibandronate at 3 years in early breast cancer
Ividiyo: No benefit for adjuvant ibandronate at 3 years in early breast cancer

Umxholo

Ibandronate isetyenziselwa ukuthintela nokunyanga i-osteoporosis (imeko apho amathambo esiba buthathaka kwaye abuthathaka kwaye aphuke ngokulula) kwabasetyhini abathe bafumana ukuyeka ukuya exesheni ('' utshintsho lobomi, '' ukuphela kwexesha lokuya exesheni). Ibandronate ikudidi lwamayeza abizwa ngokuba yi-bisphosphonates. Isebenza ngokuthintela ukophuka kwethambo kunye nokwandisa uxinano lweethambo (ubukhulu).

Ibandronate iza njengecwecwe lokuthatha ngomlomo. Ithebhulethi ye-2.5-mg ihlala ithathwa kanye ngemini kusasa kwisisu esingenanto kwaye ithebhulethi ye-150-mg ihlala ithathwa kanye ngenyanga kusasa kwisisu esingenanto. Ithebhulethi ye-150-mg kufuneka ithathwe ngomhla ofanayo inyanga nenyanga. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha ibandronate ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ibandronate isenokungasebenzi kakuhle kwaye inokonakalisa i-esophagus (ityhubhu phakathi komlomo nesisu) okanye ibangele izilonda emlonyeni ukuba ayithathiwe ngokwale miyalelo ilandelayo. Xelela ugqirha wakho ukuba awuqondi, awucingi ukuba uyakukhumbula, okanye awungekhe ukwazi ukulandela le miyalelo:

  • Kuya kufuneka uthathe ibandronate emva kokuba uvukile ebhedini kusasa, ngaphambi kokuba utye okanye usele nantoni na. Ungaze uthathe ibandronate ngexesha lokulala okanye ngaphambi kokuba uvuke uphume ebhedini usuku.
  • Ginya amacwecwe ngeglasi epheleleyo (ezi-6 ukuya kwezi-8 zee-ounces (i-180 ukuya kwi-240 mL) yamanzi acocekileyo. Ungaze uthathe ibandronate ngeti, ikofu, ijusi, ubisi, amanzi amaminerali, amanzi ahlwahlwazayo, okanye nayiphi na into engamanzi ngaphandle kwamanzi acocekileyo.
  • Ginya iipilisi ngokupheleleyo; ungahluleli, ungahlaleli, okanye uzityumze. Musa ukufunxa iipilisi.
  • Emva kokuba uthathe ibandronate, ungatyi, ungaseli, okanye uthathe amanye amayeza (kubandakanya iivithamini okanye ii-antacids) ubuncinci imizuzu engama-60. Sukulala phantsi ubuncinci imizuzu engama-60 emva kokuba uthathe ibandronate. Hlala nkqo okanye ume nkqo kangangemizuzu engama-60.

Ibandronate control osteoporosis kodwa ayiyinyangi. Ibandronate inceda ukunyanga nokukhusela i-osteoporosis kuphela ukuba ithathwa rhoqo. Qhubeka nokuthatha ibandronate nokuba uziva uphilile. Sukuyeka ukuthatha ibandronate ungakhange uthethe nogqirha wakho, kodwa thetha nogqirha wakho amaxesha ngamaxesha malunga nokuba usafuna ukuthatha ibandronate.


Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-ibandronate kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe ibandronate,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-ibandronate, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-ibandronate. Buza usokhemesti wakho uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Ibu-Tab, Motrin, ezinye) kunye ne-naproxen (Aleve, Naprelan, Naprosyn, nezinye); umhlaza chemotherapy; kunye nee-steroids zomlomo ezinje nge-dexamethasone, methylprednisolone (Medrol), kunye ne-prednisone (iRayos). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • ukuba uthatha nawaphi na amayeza omlomo, kubandakanya izongezo, iivithamini, okanye ii-antacids, zithathe ubuncinci imizuzu engama-60 emva kokuba uthathe ibandronate.
  • xelela ugqirha wakho ukuba awukwazi ukuhlala nkqo okanye ume nkqo ubuncinci imizuzu engama-60 kwaye ukuba ukhe wanayo inqanaba eliphantsi le-calcium egazini lakho. Ugqirha wakho unokukuxelela ukuba ungathathi ibandronate.
  • xelela ugqirha wakho ukuba ngaba ufumana unyango lwe-radiation kwaye ukuba unayo okanye wakhe wanayo i-anemia (imeko apho iiseli ezibomvu zegazi zingazisi i-oksijini eyaneleyo kuwo onke amalungu omzimba); ubunzima bokugwinya; isilungulela; izilonda okanye ezinye iingxaki kwisisu sakho okanye kwi-esophagus (ityhubhu edibanisa umqala nesisu); umhlaza; naluphi na uhlobo losulelo, ngakumbi emlonyeni wakho; iingxaki ngomlomo, ngamazinyo, okanye ngeentsini; nayiphi na imeko emisa igazi lakho ekunqandeni ngesiqhelo; okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Xelela ugqirha wakho ukuba ucwangcisa ukukhulelwa nanini na kwixa elizayo, kuba ibandronate inokuhlala emzimbeni wakho iminyaka emva kokuyeka ukuyithatha. Biza ugqirha wakho ukuba ukhulelwe ngexesha okanye emva konyango lwakho.
  • Kuya kufuneka uyazi ukuba ibandronate inokubangela i-osteonecrosis yomhlathi (ONJ, imeko enzima yethambo lomhlathi), ngakumbi ukuba uqhaqho lwamazinyo okanye unyango ngelixa uthatha amayeza. Ugqirha wamazinyo kufuneka ahlolisise amazinyo akho kwaye enze naluphi na unyango olufunekayo, kubandakanya ukucoca okanye ukulungisa amazinyo afakelweyo ngendlela engeyiyo, ngaphambi kokuba uqale ukuthatha ibandronate. Qiniseka ukuba uhlamba amazinyo kwaye ucoce umlomo wakho ngokufanelekileyo ngelixa uthatha ibandronate. Thetha nogqirha wakho ngaphambi kokuba ufumane unyango lwamazinyo ngelixa uthatha eli yeza.
  • Kuya kufuneka uyazi ukuba ibandronate inokubangela amathambo aqatha, umsipha, okanye iintlungu ezidibeneyo. Ungaqala ukuziva le ntlungu ngaphakathi kweentsuku, iinyanga, okanye iminyaka emva kokuba uqale uthathe ibandronate. Nangona olu hlobo lweentlungu lungaqala emva kokuba uthathe i-ibandronate kangangexesha elithile, kubalulekile kuwe nogqirha wakho ukuba niqonde ukuba kunokubangelwa yi-ibandronate. Biza ugqirha wakho ngoko nangoko ukuba ufumana iintlungu ezinzima nangaliphi na ixesha ngexesha lonyango lwakho nge-ibandronate. Ugqirha wakho angakuxelela ukuba uyeke ukuthatha ibandronate kwaye iintlungu zakho zinokuhamba emva kokuba uyekile ukuthatha amayeza.
  • thetha nogqirha wakho ngezinye izinto onokuzenza ukuthintela i-osteoporosis ekuphuhliseni okanye ekubandezelekeni. Ugqirha wakho uya kuthi kukuthintele ukutshaya nokusela izixa ezikhulu zotywala kwaye ulandele inkqubo eqhelekileyo yokuthwala ubunzima.

Kuya kufuneka utye kwaye usele ukutya okuninzi kunye neziselo ezityebileyo kwi-calcium kunye nevithamin D ngelixa uthatha ibandronate. Ugqirha wakho uya kukuxelela ukuba kukuphi ukutya kunye neziphuzo eziyimithombo elungileyo yezi zondlo kunye nokuba zingaphi iinkonzo ozidingayo suku ngalunye. Ukuba ukufumanisa kunzima ukutya oku kutya ngokwaneleyo, xelela ugqirha wakho. Kwimeko apho, ugqirha wakho unokumisela okanye acebise isongezelelo.


Ukuba ulibale ukuthatha ipilisi ye-2.5-mg yemihla ngemihla, ungayithathi kamva emini. Tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo kusasa. Musa ukuthatha iipilisi ezimbini ze-ibandronate ngosuku olunye.

Ukuba ulibale ukuthatha ipilisi ye150-mg kanye ngenyanga, kwaye usuku lwakho olulandelayo lokucwangciswa ukuthatha ibandronate ingaphezulu kweentsuku ezisi-7 kude, thabatha ithebhulethi enye kusasa emva kokuba ukhumbule. Emva koko buyela ekuthatheni ipilisi enye ngenyanga nganye ngomhla ocwangciswe rhoqo. Ukuba ulibale ukuthatha ipilisi ye150-mg kanye ngenyanga kunye nosuku lwakho olulandelayo lokucwangciswa ukuthatha ibandronate ziintsuku ezi-7 okanye ezimbalwa kude, tsiba idosi kwaye ulinde usuku lwakho olulandelayo. Akufuneki uthathe iipilisi ezimbini ze-150-mg ze-ibandronate kwiveki e-1.

Ukuba awuqinisekanga ukuba wenzeni ukuba uphoswa yidosi ye-ibandronate, tsalela ugqirha wakho.

Ibandronate inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • isicaphucaphu
  • isisu esibuhlungu
  • urhudo
  • ukuqhina
  • ubuthathaka
  • isiyezi
  • intloko ebuhlungu
  • umkhuhlane, umqala obuhlungu, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
  • Rhoqo okanye ngokungxamisekileyo isidingo sokuchama
  • ukuchama kabuhlungu

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko ngaphambi kokuba uthathe elinye ibandronate:

  • isitshisa esitsha okanye esibi
  • kunzima ukugwinya
  • intlungu ekuginyeni
  • iintlungu zesifuba
  • irhashalala
  • iintsini ezibuhlungu okanye ezidumbileyo
  • ukukhululeka kwamazinyo
  • ukuba ndindisholo okanye ukuziva unzima emhlathini
  • ukuphilisa kakubi umhlathi
  • buthuntu, iintlungu zibuhlungu esinqeni, emiphakathini, okanye emathangeni

Ibandronate inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.


Ukuthatha amayeza e-bisphosphonate anje nge-ibandronate ye-osteoporosis inokunyusa umngcipheko wokuba wophule amathambo akho. Ungaziva iintlungu esinqeni, emthanjeni, okanye emathangeni kangangeeveki okanye iinyanga ngaphambi kokuba amathambo aqhekeke, kwaye ungafumanisa ukuba elinye okanye omabini amathambo akho aphukile nangona ungakhange uwe okanye ufumane olunye umothuko. Akuqhelekanga ukuba ithambo lethanga liphule kubantu abasempilweni, kodwa abantu abane-osteoporosis banokulophula eli thambo nokuba abayithathi ibandronate. Thetha nogqirha wakho malunga nemingcipheko yokuthatha ibandronate.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokudlula ngaphezulu, nika ixhoba iglasi yobisi kwaye ubize iziko lakho lolawulo lwetyhefu kwindawo yoku-1-800-222-1222. Ukuba ixhoba liye lawa okanye aliphefumli, tsalela umnxeba iinkonzo zongxamiseko zasekuhlaleni ngo-911. Sukuvumela ixhoba ukuba lilale phantsi kwaye ungazami ukuligabha ixhoba.

Iimpawu libanda kungaquka oku kulandelayo:

  • isicaphucaphu
  • isisu esibuhlungu
  • isilungulela

Gcina lonke ixesha lokudibana nogqirha wakho. Ugqirha wakho unokuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwi-ibandronate.

Ngaphambi kokuba ufundwe ngethambo lokucinga, xelela ugqirha wakho kunye nabasebenzi bezempilo ukuba uthatha ibandronate.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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