ICaplacizumab-yhdp Inaliti

Umxholo

• Ngaphambi kokufumana i-caplacizumab-yhdp,
• ICaplacizumab-yhdp inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti yeCaplacizumab-yhdp isetyenziselwa ukunyanga i-thrombotic thrombocytopenic purpura (aTTP; ukuphazamiseka apho umzimba uhlasela khona kwaye ubangele amahlwili, izixa zeeplatelets eziphantsi kunye neeseli ezibomvu zegazi, kwaye kunokubangela ezinye iingxaki) ngokudibene nonyango lotshintshiselwano ngeplasma kunye iyeza lokuzikhusela emzimbeni. ICaplacizumab-yhdp ikudidi lwamayeza abizwa ngokuba ziiarhente ze-antithrombotic. Isebenza ngokuthintela isenzo sento ethile emzimbeni ebangela iimpawu ze-TTP.

ICaplacizumab-yhdp iza njengepowder ukuba inyibilike kulwelo kwaye inikwe nge-intravenous (kwi-vein) okanye i-subcutaneous (phantsi kolusu) inaliti. Ihlala inikezelwa kusuku lokuqala lonyango njengesitofu sokufaka inaliti okungenani imizuzu eli-15 ngaphambi kokutshintshiselana ngeplasma, kwaye kwakhona kwakhona ngenaliti engaphantsi emva kokugqitywa kokutshintshwa kweplasma. Emva kosuku lokuqala lonyango kudla ngokunikezelwa ngenaliti yangaphambi kwemihla ngemihla yokulandela ukutshintshwa kweplasma ixesha elide ufumana unyango lotshintshiselwano ngeplasma, kwaye kube kanye yonke imihla ngeentsuku ezingama-30 ukuya kwezingama-58 emva kokuyeka unyango lotshintshiselwano ngeplasma. Sebenzisa i-caplacizumab-yhdp ngexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-caplacizumab-yhdp ngokuchanekileyo njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ugqirha wakho unokukuvumela okanye umnakekeli ukuba enze inaliti ekhaya. Buza ugqirha wakho okanye usokhemesti akubonise okanye umntu oza kwenza inaliti indlela yokulungisa kunye nokutofa i-caplacizumab-yhdp. Ngaphambi kokuba usebenzise i-caplacizumab-yhdp inaliti ngokwakho okokuqala, funda imiyalelo ebhaliweyo eza nayo. Buza usokhemesti okanye ugqirha wakho ngekopi yemiyalelo yomenzi yokusebenzisa ulwazi lwesigulana.

Kuya kufuneka utofe inaliti ye-caplacizumab-yhdp ngokungxama kwisisu (esiswini) indawo kodwa thintela inkaba yakho kunye nendawo eyi-intshi ezi-5 (iisentimitha ezi-5) ngeenxa zonke. Musa ukujova kwindawo enye iintsuku ezimbini zilandelelana.

Lahla iinaliti, iisirinji kunye neebhotile kwisitya esinganyangekiyo. Thetha nogqirha wakho okanye usokhemesti malunga nokusilahla isikhongozeli esinganyangekiyo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-caplacizumab-yhdp,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba u-aleji kwi-caplacizumab-yhdp, nawaphi na amanye amayeza, okanye nasiphi na isithako esenziwe kwi-caplacizumab-yhdp injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: apixaban (Eliquis), clopidogrel (Plavix), dabigatran (Pradaxa), dipyrimadole (Persantine, in Aggrenox), edoxaban (Savaysa), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin, prasugrel (Esebenzayo), i-rivaroxaban powder (i-Xarelto), i-ticagrelor (i-Brilinta), okanye i-warfarin (i-Coumadin, i-Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe okanye wakha wanesifo (i-genetic disorder apho umzimba ungakwazi ukuyeka ukopha ngokufanelekileyo) okanye ezinye iingxaki zokopha, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana i-caplacizumab-yhdp, tsalela ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-caplacizumab-yhdp. Ugqirha wakho okanye ugqirha wamazinyo unokukuxelela ukuba ungasebenzisi i-caplacizumab-yhdp kangangeentsuku ezisi-7 ngaphambi kotyando.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Sebenzisa idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba awusafumani lonyango lotshintshiselwano ngeplasma, kwaye ngaphezulu kweeyure ezili-12 sele idlulile idosi ephosiweyo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo. Sukusebenzisa idosi ephindwe kabini ukwenza eyilahlekileyo.

ICaplacizumab-yhdp inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukudinwa kakhulu
• umqolo obuhlungu
• iintlungu zemisipha
• ukurhawuzelela, ukurhawuzelela, okanye ukuziva urhabaxa kulusu
• ukurhawuzelela kufutshane nendawo apho iyeza lafakwa khona
• ukuqhawukelwa ngumphefumlo
• ifiva

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• urhwebo
• ukopha okunzima okungayi kuyeka ukopha kwi-rectum, ubufazi, impumlo, iintsini okanye indawo apho lalifakwe khona iyeza
• ukugabha igazi
• ebomvu, okanye emnyama, izitulo zokulinda
• igazi kumchamo
• intloko ebukhali ngesiquphe, isicaphucaphu, ukugabha
• ngequbuliso, iintlungu ezibukhali esiswini, isicaphucaphu, ukugabha
• Ukuchama rhoqo, okubuhlungu, okanye okungxamisekileyo

I-Caplacizumab-yhdp inaliti inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina kwifriji, kwaye kude nokukhanya. Musa ukubanda. Inaliti yeCaplacizumab-yhdp inokugcinwa kubushushu begumbi ukuya kuthi ga kwiinyanga ezi-2 kodwa kufuneka igcinwe kwikhathoni yoqobo ukukhusela ekukhanyeni. ICaplacizumab-yhdp akufuneki ibuyiselwe kwifriji emva kokuba igcinwe kubushushu begumbi.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukopha

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zelebhu ukujonga ukuba ngaba unyango nge-caplacizumab-yhdp kufuneka luqhubeke na.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya.Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICablivi^®