Inaliti yeFludarabine

Umxholo

• Ngaphambi kokufumana inaliti ye-fludarabine,
• Inaliti ye-Fludarabine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti ye-Fludarabine kufuneka inikezwe phantsi kweliso likagqirha onamava ekunikeni amayeza e-chemotherapy kumhlaza.

Inaliti ye-Fludarabine inokubangela ukwehla kwenani leeseli zegazi ezenziwe ngumongo wethambo lakho. Oku kuncipha kunokubangela ukuba ube neempawu eziyingozi kwaye kunokunyusa umngcipheko wokuba nosulelo olubi okanye olusongela ubomi. Ugqirha wakho unokuyalela amanye amayeza ukunciphisa umngcipheko wokuba uya kuba nosulelo olomeleleyo ngexesha lonyango lwakho. Xelela ugqirha wakho ukuba ukhe wanalo inani eliphantsi lalo naluphi na uhlobo lweeseli zegazi egazini lakho okanye nayiphi na imeko echaphazela amajoni akho omzimba kwaye ukuba ukhe wakha usulelo ngenxa yokuba amanqanaba eseli egazi ephantsi kakhulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngokukhawuleza: ukuphefumla kancinci; ukubetha kwentliziyo ngokukhawuleza; intloko ebuhlungu; isiyezi; ulusu oluthuthu; ukudinwa kakhulu; ukopha okungaqhelekanga okanye ukugruzuka; emnyama, yokulinda, okanye isitulo segazi; ukugabha okunegazi okanye okujongeka njengendawo yekofu; kunye nomkhuhlane, ukugodola, ukukhohlela, umqala obuhlungu, ubunzima, ubuhlungu, okanye ukuchama rhoqo, okanye ezinye iimpawu zosulelo.

Inaliti ye-Fludarabine inokubangela nomonakalo kwinkqubo yemithambo-luvo. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: ukuxhuzula, ukuphazamiseka, ukudideka, kunye ne-coma (ukulahleka kwengqondo kangangexesha elithile).

Inaliti ye-Fludarabine inokubangela iimeko ezinobungozi okanye ezisongela ubomi apho umzimba uhlasela kwaye utshabalalise iiseli zegazi. Tshela ugqirha wakho ukuba ukhe waluphuhlisa olu hlobo lwesimo emva kokufumana i-fludarabine ngaphambili. Ukuba unazo naziphi na kwezi mpawu zilandelayo, biza ugqirha wakho kwangoko: umchamo omnyama, isikhumba esimthubi, amachaphaza amancinci abomvu okanye mfusa kulusu, ukuphuma kweempumlo, ukuphuma kwegazi okunzima, igazi kumchamo, ukukhwehlela igazi, okanye ubunzima bokuphefumla ngenxa yokopha emqaleni.

Kwisifundo seklinikhi, abantu abane-lymphocytic leukemia engapheliyo abasebenzisa inaliti ye-fludarabine kunye ne-pentostatin (Nipent) basemngciphekweni omkhulu wokuba nomonakalo omkhulu wemiphunga. Ngamanye amaxesha, lo monakalo wemiphunga wabangela ukufa. Ke ngoko, ugqirha wakho akazukuyalela ngenaliti ye-fludarabine ukuba inikezwe kunye nepentostatin (Nipent).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile ukujonga impendulo yomzimba wakho kwinaliti ye-fludarabine.

Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-fludarabine.

Inaliti ye-Fludarabine isetyenziselwa ukunyanga i-lymphocytic leukemia (CLL; uhlobo lomhlaza weeseli ezimhlophe zegazi) kubantu abadala abasele bephethwe ngamanye amayeza kwaye bengangcono. Inaliti ye-Fludarabine ikudidi lwamayeza abizwa ngokuba zii-analine ze-purine. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

Inaliti ye-Fludarabine iza njengomgubo oza kongezwa kulwelo kwaye itofwe ngaphezulu kwemizuzu engama-30 efakwa ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiofisi yezonyango okanye kwikliniki yezigulana ezingalaliswayo. Ihlala itofwe kanye ngemini kangangeentsuku ezintlanu zilandelelana. Eli xesha lonyango libizwa ngokuba ngumjikelo, kwaye umjikelo unokuphindwa rhoqo kwiintsuku ezingama-28 kwimijikelezo eliqela.

Ugqirha wakho unokufuna ukulibazisa unyango lwakho okanye uhlengahlengise idosi yakho ukuba uneziphumo ebezingalindelekanga ezithile. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-fludarabine.

Inaliti ye-Fludarabine ngamanye amaxesha isetyenziselwa ukunyanga i-non-Hodgkin's lymphoma (NHL; umhlaza oqala kuhlobo lweeseli ezimhlophe zegazi ezihlala zilwa nosulelo) kunye ne-mycosis fungoides (uhlobo lwe-lymphoma echaphazela ulusu). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-fludarabine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-fludarabine, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ze-fludarabine. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qinisekisa ukukhankanya amayeza adweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO okanye icytarabine (Cytosar-U, DepoCyt). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• Xelela ugqirha wakho ukuba ukhe waba nesifo sezintso kwaye uxelele ugqirha wakho ngawo onke amayeza e-chemotherapy owafumeneyo kwaye ukuba ukhe wanyangwa ngonyango lwemitha (unyango lomhlaza olusebenzisa amaza amasuntswana amandla ukubulala iiseli zomhlaza. ). Ngaphambi kokuba ufumane i-chemotherapy okanye unyango lwe-radiation kwikamva, xelela ugqirha wakho ukuba uphathwe nge-fludarabine.
• Kuya kufuneka uyazi ukuba inaliti ye-fludarabine inokuphazamisa umjikelo oqhelekileyo wokuya exesheni (ixesha) kwabasetyhini kwaye inokuyeka ukuveliswa kwesidoda emadodeni. Nangona kunjalo, awufanelanga ukucinga ukuba wena okanye iqabane lakho aninakukhulelwa. Ukuba ukhulelwe okanye uncancisa, kuya kufuneka uxelele ugqirha wakho ngaphambi kokuba uqale ukufumana eli yeza. Akufanele ucwangcise ukuba nabantwana ngelixa ufumana inaliti ye-fludarabine okanye ubuncinci iinyanga ezi-6 emva konyango. Sebenzisa indlela ethembekileyo yolawulo lokuzalwa ukukhusela ukukhulelwa ngeli xesha. Thetha nogqirha wakho ukuze ufumane ezinye iinkcukacha. Inaliti ye-Fludarabine inokulimaza umbungu.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-fludarabine.
• Kuya kufuneka uyazi ukuba inaliti ye-fludarabine inokubangela ukudinwa, ubuthathaka, ukudideka, ukuphazamiseka, ukuxhuzula, kunye notshintsho kumbono. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• thetha nogqirha wakho ngaphambi kokuba ufumane naluphi na ugonyo ngexesha lonyango lwakho ngenaliti ye-fludarabine.
• Kuya kufuneka uyazi ukuba unokuhlakulela ukusabela okunobuzaza okanye okusongela ubomi ukuba ufuna ukufumana utofelo-gazi ngexesha lonyango lwakho ngenaliti ye-fludarabine okanye nangaliphi na ixesha emva konyango lwakho. Qiniseka ukuba uxelela ugqirha wakho ukuba ufumana okanye ufumene inaliti ye-fludarabine ngaphambi kokuba utofelwe igazi.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Inaliti ye-Fludarabine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• Ukuphelelwa ngumdla wokutya
• isicaphucaphu
• ukugabha
• ukuqhina
• urhudo
• izilonda zomlomo
• ukulahleka kweenwele
• ukuba ndindisholo, ukutshisa, iintlungu, okanye ukurhawuzelelwa zizandla, iingalo, iinyawo, okanye imilenze
• intlungu yesihlunu okanye edibeneyo
• intloko ebuhlungu
• ukudakumba
• iingxaki zokulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• Intlungu yesifuba okanye ukungonwabi
• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• ukulahlekelwa kwindlebe
• iintlungu ecaleni komzimba
• ukudumba kweengalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• irhashalala
• urhwebo
• ubunzima bokuphefumla okanye ukugwinya
• Ukuxobuka okanye ukudumba kolusu

Inaliti ye-Fludarabine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukugruzuka okanye ukopha okungaqhelekanga
• umkhuhlane, ukugodola, ukukhohlela, umqala obuhlungu, okanye ezinye iimpawu zosulelo
• ukulibaziseka kobumfama
• ikhoma

Buza ugqirha wakho okanye usokhemesti ukuba unayo nayiphi na imibuzo malunga nenaliti ye-fludarabine.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UFludara^®

• I-2-Fluoro-ara-A Monophosphate, 2-Fluoro-ara AMP, FAMP