I-Collagenosis: yintoni, izizathu eziphambili kunye nendlela yokunyanga

Umxholo

• 1. ILupus
• 2. Iscleroderma
• 3. Isifo sikaSjogren
• 4. Dermatomyositis
• Indlela yokuqinisekisa ukuxilongwa
• Ungayinyanga njani i-collagenosis
• Kutheni le nto isenzeka

I-Collagenosis, ekwabizwa ngokuba sisifo se-collagen, ibonakaliswa liqela lezifo ezizimela kunye nezifo ezenzakalisayo ezenzakalisa izicwili zomzimba, ezilulusu olwenziwe yimicu, njenge-collagen, kwaye inoxanduva lwemisebenzi njengokugcwalisa izithuba phakathi amalungu, anike inkxaso, ukongeza kunceda ekukhuseleni umzimba.

Utshintsho olwenziwe yi-collagenosis lunokuchaphazela amalungu ahlukeneyo kunye neenkqubo zomzimba, ezinjengesikhumba, imiphunga, imithambo yegazi kunye nezicubu ze-lymphatic, umzekelo, kwaye zivelise ikakhulu iimpawu zesikhumba kunye nerheumatological, ezibandakanya iintlungu, ukudumba kolusu, utshintsho kolusu , ukujikeleza kwegazi okanye umlomo owomileyo namehlo.

Ezinye ze-collagenoses eziphambili zizifo ezinjenge:

1. ILupus

Sisona sifo siphambili somzimba, esenza umonakalo kumalungu nakwiiseli ngenxa yesenzo se-autoantibodies, kwaye ixhaphake kakhulu kubafazi abancinci, nangona inokwenzeka nakubani na. Isizathu saso asikaziwa ngokupheleleyo, kwaye esi sifo sihlala sikhula kancinci kwaye ngokuqhubekekayo, sineempawu ezinokuthi zibe mncinci ukuya kwezomeleleyo, ezohluka ukusuka komnye umntu ukuya komnye.

Iimpawu kunye neempawu: I-lupus inokubangela iintlobo ezahlukeneyo zokubonakaliswa kweklinikhi, ukusuka ekuhlaleni ukuya kusasazwa kuwo wonke umzimba, kubandakanya iziphako zolusu, izilonda zomlomo, isifo samathambo, ukuphazamiseka kwezintso, ukuphazamiseka kwegazi, ukudumba kwemiphunga nentliziyo.

Funda ngakumbi malunga nokuba yintoni kunye nendlela yokuchonga i-lupus.

2. Iscleroderma

Sisifo esidala ukuqokeleleka kwemicu ye-collagen emzimbeni, yesizathu esingaziwayo, kwaye ichaphazela ikakhulu ulusu kunye namalungu, kwaye inokuchaphazela nokuhamba kwegazi kunye namanye amalungu angaphakathi, anje ngemiphunga, intliziyo, izintso kunye neendlela zesisu.

Iimpawu kunye neempawu: kuhlala kukho ukuqina kolusu, okuye kube nzima ngakumbi, kukhazimle kwaye kube nobunzima bokujikeleza, okuye kusiba kubi ngokuthe chu nangokuqhubekayo. Xa ifikelela kumalungu angaphakathi, ngohlobo olwahlukileyo, inokubangela ubunzima bokuphefumla, utshintsho olwetyisayo, ukongeza kwimisebenzi yentliziyo kunye nezintso, umzekelo.

Ukuqonda ngcono iimpawu zeentlobo eziphambili ze-scleroderma kunye nendlela yokuyinyanga.

3. Isifo sikaSjogren

Olunye uhlobo lwesifo se-autoimmune, esibonakaliswa kukungena kweeseli zokhuselo kwiincindi zomzimba, kuthintela ukuveliswa kwemfihlo ngamadlala amabi kunye namathe. Esi sifo sixhaphake kakhulu kwabasetyhini abaphakathi, kodwa sinokubakho nakubani na, kwaye sinokubonakala sodwa okanye sikhatshwa zizifo ezifana ne-rheumatoid arthritis, lupus, scleroderma, vasculitis okanye hepatitis, umzekelo.

Iimpawu kunye neempawu: umlomo owomileyo namehlo zezona mpawu ziphambili, ezinokuthi zibe mandundu ngokuthe ngcembe kwaye ziqhubeke ngokuthe ngcembe, kwaye zibangele ubomvu, ukutsha kunye nemvakalelo yesanti emehlweni okanye ubunzima bokuginya, ukuthetha, ukwanda kokubola kwamazinyo kunye nokutsha okutshisayo emlonyeni. Iimpawu kwamanye amalungu omzimba zinqabile, kodwa zinokubandakanya ukudinwa, umkhuhlane kunye nentlungu edibeneyo kunye nemisipha, umzekelo.

Ukuqonda ngcono indlela yokuchonga kunye nokuchonga isifo sikaSjogren.

4. Dermatomyositis

Ikwaluhlobo lwesifo esizenzekelayo esihlasela size sithintele izihlunu kunye nolusu. Xa ichaphazela kuphela izihlunu, inokwaziwa ngokuba yi-polymyositis. Unobangela wayo awaziwa, kwaye unokuvela kubantu bayo yonke iminyaka.

Iimpawu kunye neempawu: kuqhelekile ukuba buthathaka kwezihlunu, okuxhaphakileyo esiqwini, kuthintele ukuhamba kweengalo kunye nesinqe, njengokukama iinwele okanye ukuhlala / ukuma nkqo. Nangona kunjalo, nasiphi na isihlunu sinokufikelelwa, sibangele ubunzima ekuginyeni, ekushukumiseni intamo, ukuhamba okanye ukuphefumla, umzekelo. Izilonda zolusu zibandakanya amabala abomvu okanye ansundu kunye neflake enokuthi ibe mandundu nelanga.

Fumana iinkcukacha ezithe kratya malunga nendlela yokuchonga kunye nokunyanga i-dermatomyositis.

Indlela yokuqinisekisa ukuxilongwa

Ukuchonga i-collagenosis, ukongeza kuvavanyo lweklinikhi, ugqirha unokuyalela uvavanyo lwegazi oluchonga ukudumba kunye nezibulala-ntsholongwane ezikhoyo kwezi zifo, ezinje nge-FAN, Mi-2, SRP, Jo-1, Ro / SS-A okanye I-La / SS- B, umzekelo. Ii-Biopsies okanye uhlalutyo lwezicubu ezinokudumba nako kunokuba yimfuneko.

Ungayinyanga njani i-collagenosis

Unyango lwe-collagen, kunye nasiphi na isifo se-autoimmune, luxhomekeke kuhlobo lwaso kunye nobukhali, kwaye kufuneka sikhokelwe yi-rheumatologist okanye i-dermatologist. Ngokubanzi, kubandakanya ukusetyenziswa kwee-corticosteroids, ezinje ngePrednisone okanye iPrednisolone, ukongeza kwezinye i-immunosuppressants ezinamandla okanye i-immune system regulators, ezinje ngeAzathioprine, Methotrexate, Cyclosporine okanye iRituximab, umzekelo, njengendlela yokulawula ukungakhuseleki kunye nokunciphisa iziphumo zayo umzimba.

Ukongeza, amanye amanyathelo afana nokukhuselwa lilanga ukukhusela izilonda kulusu, kunye nokuhla kwamehlo okwenziweyo okanye amathe ukunciphisa ukoma kwamehlo nomlomo, zinokuba zezinye iindlela zokunciphisa iimpawu.

I-Collagenosis ayinalo unyango, nangona kunjalo inzululwazi ifune ukuphuhlisa iindlela zonyango zangoku, esekwe kulawulo lokuzikhusela kwi-immunotherapy, ukuze ezi zifo zilawulwe ngokukuko.

Kutheni le nto isenzeka

Okwangoku akukho sizathu sicacileyo sokuvela kweqela lezifo ezizimela ngokwazo ezibangela i-collagenosis. Nangona zidibene nokungalunganga kunye nokusebenzisa kakhulu amajoni omzimba, akwaziwa ukuba yintoni kanye kanye ebangela le meko.

Kusenokwenzeka ukuba kukho iindlela zemvelo kunye neendlela zokusingqongileyo, ezinje ngendlela yokuphila kunye nendlela otya ngayo, njengonobangela wezi zifo, nangona kunjalo, isayensi kusafuneka ukuba ibone ngcono oku kurhaneleka ngokuqhubeka nezifundo.