Umbhali: Lewis Jackson
Umhla Wokudalwa: 6 Ucanzibe 2021
Hlaziya Umhla: 1 Eyenkanga 2024
Anonim
Iimpawu kunye neMpawu ze-Estrogen ePhakamileyo - Zempilo
Iimpawu kunye neMpawu ze-Estrogen ePhakamileyo - Zempilo

Umxholo

Yintoni i-estrogen?

Iihomoni zomzimba wakho zinjengomhlathana. Xa zilungelelene ngokugqibeleleyo, umzimba wakho usebenza njengoko kufanelekile. Kodwa xa zingalungelelananga, usenokuqalisa ukuba neengxaki.

I-Estrogen yaziwa ngokuba yihomoni "yabasetyhini". I-testosterone yaziwa njengehomoni "eyindoda". Nangona ihomoni nganye ichongwa ngesondo esithile, zombini ziyafumaneka kwabasetyhini nakumadoda. Ngokomndilili, abasetyhini banamanqanaba aphezulu e-estrogen kwaye amadoda ane testosterone ngakumbi.

Kwabasetyhini, i-estrogen iyanceda ukuqalisa ukukhula ngokwesondo. Kunye nenye ihomoni yesini yabasetyhini eyaziwa ngokuba yiprogesterone, ikwalawula kwakhona umjikelo wokuya exesheni kwabasetyhini kwaye ichaphazele yonke inkqubo yokuzala. Kubasetyhini be-premenopausal, amanqanaba e-estrogen kunye neprogesterone ayahluka ukusuka kwinqanaba lokuya esikhathini ukuya kwelinye.

Kumadoda, i-estrogen ikwadlala indima ebalulekileyo ekusebenzeni ngokwesondo.

Oonobangela be-estrogen ephezulu

Amanqanaba aphezulu e-estrogen anokukhula ngokwemvelo, kodwa i-estrogen eninzi inokubangelwa kukuthatha amayeza athile. Umzekelo, unyango lwe-estrogen, unyango oluthandwayo lweempawu zokuyeka ukuya exesheni, kunokubangela ukuba i-estrogen ifikelele kumanqanaba anengxaki.


Umzimba wakho unokukhulisa i-testosterone esezantsi okanye amanqanaba asezantsi eprogesterone, anokuphazamisa ibhalansi yehomoni. Ukuba unamazinga e-estrogen aphezulu ngokungaqhelekanga kumanqanaba akho eprogesterone, yaziwa ngokuba yi-estrogen dominance.

Iimpawu ze-estrogen ephezulu kubafazi

Xa amanqanaba e-estrogen kunye ne-testosterone yomzimba wakho engalingani, ungaqala ukuphuhlisa iimpawu ezithile. Kwabasetyhini, iimpawu ezinokubakho zibandakanya:

  • ukudumba
  • ukudumba nokuthamba emabeleni akho
  • amaqhuma e-fibrocystic emabeleni akho
  • ukwehla kwesondo
  • amaxesha okungaqhelekanga okuya esikhathini
  • ukwanda kweempawu zesifo sokuqala (PMS)
  • ukuhamba kweemvakalelo
  • intloko ebuhlungu
  • unxunguphalo kunye noloyiko
  • ukutyeba kwakho
  • ukulahleka kweenwele
  • izandla ezibandayo okanye iinyawo
  • ingxaki yokulala
  • ukozela okanye ukudinwa
  • iingxaki zememori

Iimpawu ze-estrogen ephezulu emadodeni

Nangona ibizwa ngokuba yihomoni yabasetyhini, umzimba wendoda nawo wenza i-estrogen. Ibhalansi esempilweni ye-estrogen kunye ne-testosterone ibalulekile ekukhuleni ngokwesondo kunye nakuphuhliso. Xa ezi hormone zingalingani, ukukhula kwakho ngokwesondo kunye nokusebenza kunokuchaphazeleka.


Iimpawu ze-estrogen ephezulu kumadoda zibandakanya:

  • Ukungachumi. I-Estrogen inoxanduva lokudala isidoda esisempilweni. Xa amanqanaba e-estrogen ephezulu, amanqanaba esidoda angawa kwaye akhokelele kwimicimbi yokuzala.
  • Gynecomastia. I-Estrogen inokuvuselela ukukhula kwethishu yamabele. Amadoda ane-estrogen kakhulu anokukhulisa i-gynecomastia, imeko ekhokelela kumabele amakhulu.
  • Ukungasebenzi kakuhle kwe-Erectile (ED). Amadoda anamanqanaba aphezulu e-estrogen kunokuba nzima ukufumana okanye ukugcina ulwakhiwo.

Ukuchonga i-estrogen ephezulu

Ukuba ugqirha wakho ukrokrela ukuba unokuba ne-estrogen ephezulu, baya kuthi baodole uvavanyo lwegazi ukujonga amanqanaba akho ehomoni. Ingcali eqeqeshiweyo iya kuqokelela isampulu yegazi lakho ukuze ivavanywe elebhu. Iziphumo ziya kubonisa ukuba amanqanaba e-estrogen aphantsi kakhulu okanye aphezulu kakhulu. Amanqanaba egazi e-estrogen alinganiswa kwiipikogram ngeemililitha (pg / mL).

Zintathu iintlobo ze-estrogen: estradiol, estriol, kunye ne-estrone. I-Estradiol yeyona hormone yamabhinqa iphambili. I-Estriol kunye ne-estrone ziihomoni ezincinci zesini sabasetyhini. I-Estriol iphantse ingabonakali kubafazi abangakhulelwanga.


Amanqanaba aqhelekileyo e-estrogen kwabasetyhini

Ngokwe-Mayo Medical Laboratories, la manqanaba alandelayo e-estrone kunye ne-estradiol athathwa njengesiqhelo kwabafazi:

I-Estrone I-Estradiol
Umfazi oyintombazanaAyibonakali – 29 pg / mLAyibonakali- 20 pg / ml
Umfazi opapashiweyo10-200 pg / mLAyibonakali – 350 pg / ml
I-premenopausal yabantu abadala ababhinqileyo17-200 iphe / mlI-15-350 pg / ml
I-postmenopausal yabantu abadala ababhinqileyo7-40 ipg / mL<10 ipg / ml

Kumantombazana angaphambi kokuya esikhathini kunye nabasetyhini, amanqanaba e-estradiol ahluka kakhulu kumjikelo wokuya esikhathini.

Amanqanaba aqhelekileyo e-estrogen emadodeni

Ngokwe-Mayo Medical Laboratories, la manqanaba alandelayo e-estrone kunye ne-estradiol athathwa njengesiqhelo emadodeni:

I-Estrone I-Estradiol
Indoda eyindoda yokuqalaAyibonakali- 16 pg / mlAyibonakali-13 pg / ml
Indoda eyindodaAyibonakali- 60 pg / mlAyibonakali – 40 pg / ml
Indoda endalaI-10-60 pg / mlI-10-40 pg / ml

Unyango lwe-estrogen ephezulu

Ukulawula i-estrogen ephezulu okanye ukubusa kwe-estrogen, ugqirha wakho unokukunika amayeza, ukucebisa utyando, okanye ukukhuthaze ukuba uhlengahlengise indlela otya ngayo.

Amayeza

Ukuba uphuhlisa i-estrogen ephezulu ngelixa usiya kunyango lwehomoni, ugqirha wakho unokutshintsha isicwangciso sakho sonyango lwehomoni. Oku kunokunceda umzimba wakho ufezekise ibhalansi esempilweni.

Ukuba unohlobo lomhlaza onovakalelo kwi-estrogen, amanqanaba aphezulu e-estrogen angenza umhlaza ube mandundu. Ugqirha wakho unokukunika amayeza okuthintela iiseli zomhlaza ekubeni zibophe kwi-estrogen. Umzekelo, banokumisela i-tamoxifen.

Ngenye indlela, banokumisela i-aromatase inhibitor. Olu hlobo lonyango luyeka i-enzyme aromatase ekuguquleni i-androgens kwi-estrogen. Olu didi lweziyobisi lubandakanya:

  • anastrozole (Arimidex)
  • exemestane (Aromasin)
  • ilerozole (Femara)

Ngamanye amaxesha, banokuyalela iyeza eliyekisa ii-ovari zakho ekuveliseni i-estrogen. Umzekelo, banokumisela:

  • igoserelin (iZoladex)
  • leuprolide (iLupron)

Ugqirha

Ukuba unohlobo lomhlaza onovakalelo kwi-estrogen, ugqirha wakho usenokucebisa nge-oophorectomy. Olu luhlobo lotyando olusetyenziselwa ukususa ii-ovari. Kuba ii-ovari zivelisa uninzi lwe-estrogen kwimizimba yabasetyhini, ukuzisusa kwehlisa amanqanaba e-estrogen. Oku kubangela into eyaziwa ngokuba kukuyeka ukuya exesheni.

Ugqirha wakho unokuphinda acebise i-oophorectomy ukuba usemngciphekweni omkhulu wokuhlaselwa ngumhlaza webele okanye we-ovari. Unokuba semngciphekweni omkhulu ukuba enye okanye ezingaphezulu kwezi zilandelayo ziyinyani:

  • Unembali eyomeleleyo yosapho yomhlaza webele okanye umhlaza we-ovari.
  • Uvavanya uvavanyo oluqinisekileyo lotshintsho oluthile kwi I-BRCA1 okanye I-BRCA2 Uhlobo.
  • Uvavanya ukujonga utshintsho oluthile kwezinye iintlobo zofuzo ezinxulumene nomngcipheko womhlaza.

Ngokuka, ukususa zombini amaqanda kubonakala ukunciphisa umngcipheko womhlaza webele kwizigulana ezinobungozi kakhulu malunga neepesenti ezingama-50.

Ugqirha wakho unokusebenzisa unyango lwe-radiation ukwenza ii-ovari zakho zingasebenzi.

Ukutya

Ukunceda ukunciphisa amanqanaba e-estrogen, ugqirha unokucebisa utshintsho kwindlela otya ngayo. Umzekelo, banokukukhuthaza ukuba utye ukutya okunamafutha asezantsi kunye nefayibha ephezulu. Banokukukhuthaza ukuba unciphise umzimba.

Iimeko ezinxulumene ne-estrogen ephezulu

Amanqanaba aphezulu e-estrogen anokukubeka emngciphekweni omkhulu wezinye iimeko. Umzekelo, amanqanaba e-estrogen aphakamileyo angumngcipheko womhlaza webele kunye nomhlaza we-ovari. Ngokwe-American Cancer Society (ACS), ukubusa kwe-estrogen nako kunokunyusa umngcipheko womhlaza we-endometrium.

Amanqanaba aphezulu e-estrogen anokukubeka emngciphekweni omkhulu wokugungqa kwegazi kunye nokufa icala.

Ulawulo lwe-Estrogen lunokunyusa namathuba akho okuba ungasebenzi kakuhle. Oku kunokubangela iimpawu ezinje ngokudinwa kunye notshintsho kubunzima.

Thetha nogqirha wakho

Ukuba ufumana iimpawu ezingaqhelekanga, yenza idinga lokubonana nogqirha wakho. Banokukunceda ufunde ukuba ezi mpawu zibangelwa yi-estrogen ephezulu. Kubalulekile ukunyanga i-estrogen ephezulu kunye naso nasiphi na isizathu esingunobangela. Unyango lunokunceda ukunciphisa iimpawu zakho kunye nomngcipheko weengxaki.

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