I-Ursofalk yezifo zesibindi kunye ne-gallbladder

Umxholo

• Yenzelwe ntoni
• Indlela yokuthatha
• Iziphumo ebezingalindelekanga ezinokwenzeka

I-Ursofalk liyeza eliboniswe ngokuchithwa kwamatye kwi-gallbladder okanye ezinye izifo ze-gallbladder, unyango lwe-cirrhosis yokuqala ye-biliary, unyango lokugaya ukutya okungalunganga kunye notshintsho olusemgangathweni kwinyongo, phakathi kwabanye.

Esi sixhobo sinobumba be-ursodeoxycholic acid, eyinto ebonakalayo emzimbeni we-bile, nangona isixa esilinganiselweyo. Le asidi inqanda ukuhlanganiswa kwe-cholesterol kwisibindi kwaye ivuselele ukuhlanganiswa kwe-bile acids, ukubuyisela ibhalansi phakathi kwabo. Ukongeza, ikwa negalelo ekusombululeni i-cholesterol nge-bile, ukuthintela ukwenziwa kwamatye enyongo okanye ukuthanda ukunyibilika.

Yenzelwe ntoni

Ursodeoxycholic acid liyeza eliboniswe kwizifo zesibindi, i-gallbladder kunye ne-bile ducts, kwezi meko zilandelayo:

• Iigallstones ezenziwe yicholesterol kwizigulana ezithile;
• Iimpawu zesibindi sokuqala se-biliary;
• Ilitye eliyintsalela kumjelo we-gallbladder okanye amatye amatsha awenziwe emva kotyando lwemibhobho yenyongo;
• Iimpawu zokugaya okungalunganga, ezinje ngeentlungu zesisu, ukuqaqamba kwentliziyo kunye nokugcwala, ezibangelwa zizifo zenyongo;
• Utshintsho ekusebenzeni komjelo wecystic okanye i-gallbladder kunye nee-syndromes ezinxulumene noko;
• Amanqanaba aphezulu e-cholesterol okanye i-triglycerides;
• Ukuxhasa unyango ekuphelisweni kweenyongo ngamaza othusayo, akhiwa yi-cholesterol kwizigulana ezine-cholelithiasis;
• Iinguqu ezifanelekileyo kunye nobungakanani kwi-bile.

Yazi indlela yokuchonga iimpawu zenyongo.

Indlela yokuthatha

Umthamo we-Ursofalk kufuneka ugqitywe ngugqirha.

Ukusetyenziswa ixesha elide, ukuthintela ukwenziwa kwamatye, umyinge ophakathi yi-5 ukuya kwi-10 mg / kg / ngosuku, umyinge ophakathi, kwimeko ezininzi, uphakathi kwama-300 ukuya kuma-600 mg, ngosuku, ubuncinci iinyanga ezi-4 ukuya kwezi-6, kwaye inokufikelela kwiinyanga ezili-12 okanye nangaphezulu. Unyango akufuneki ludlule kwiminyaka emibini.

Kwi-syndromes yedyspeptic kunye nonyango lokugcina, iidosi ze-300 mg ngosuku zanele ngokubanzi, zahlulwe zangama-2 ukuya ku-3 olawulo, nangona kunjalo la madosi anokuguqulwa ngugqirha.

Kwizigulana ezenza unyango lokuchithwa kwenyongo, kubalulekile ukuba ujonge ukusebenza kwe-ursodeoxycholic acid, ngokusebenzisa iimviwo ze-cholecystographic, rhoqo kwiinyanga ezi-6.

Unyango olongezelelekileyo lokupheliswa kwamaza enyongo, unyango lwangaphambili nge-ursodeoxycholic acid inyusa iziphumo zonyango. Imithamo ye-ursodeoxycholic acid kufuneka ihlengahlengiswe ngugqirha, nge-avareji ye-600 mg ngosuku.

Kwi-cirrhosis yokuqala ye-biliary, amathamo ayahluka ukusuka kwi-10 ukuya kwi-16 mg / kg / ngosuku, ngokwamanqanaba esi sifo. Kuyacetyiswa ukubeka iliso kwizigulana ngokuvavanywa kokusebenza kwesibindi kunye nomlinganiso we-bilirubin.

Idosi yemihla ngemihla kufuneka ilawulwe amaxesha ama-2 okanye ama-3, kuxhomekeke kwintetho esetyenzisiweyo, emva kokutya.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo eziqhelekileyo ezichaphazelekayo ezinokuthi zenzeke ngexesha lonyango kunye ne-Ursofalk zitshintshile ukuhambelana kwesigxina, esinokuthi sibe yipasty, okanye isifo sohudo.

Ngubani ongafanele asebenzise

I-Ursofalk akufuneki isetyenziswe kwimeko ye-allergies kwi-ursodeoxycholic acid okanye nakweliphi na icandelo lolwakhiwo, abantu abanesifo sezilonda esisebenzayo, isifo sokudumba kunye nezinye iimeko zamathumbu amancinci, ikholoni kunye nesibindi, ezinokuthi ziphazamise ukujikeleza kwe-enterohepatic Iityuwa ze-bile, i-colic biliary rhoqo, ukudumba okukhulu kwe-gallbladder okanye i-biliary tract, i-biliary tract occlusion, isivumelwano se-gallbladder okanye i-radiopaque calcified gallstones.

Ukongeza, eli yeza akufuneki lisetyenziswe ngabafazi abakhulelweyo ngaphandle kwengcebiso zonyango.