Iimpawu kunye neMpawu zeZinc Overdose

Umxholo

• 1. Isicaphucaphu nokuHlanza
• 2. Intlungu yesisu kunye nohudo
• 3. Iimpawu ezinjengomkhuhlane
• 4. Cholesterol yeHDL esezantsi "elungileyo"
• 5. Utshintsho kwiTaste yakho
• 6. Ukusilela kweCopper
• 7. Izifo ezenzeka rhoqo
• Ukhetho kunyango
• Umgca osezantsi

I-Zinc iyiminerali ebalulekileyo ebandakanyekayo ekuphenduleni kwamakhemikhali angaphezu kwe-100 emzimbeni wakho.

Kuyimfuneko ekukhuleni, ukuhlanganiswa kwe-DNA kunye nokuqonda okuqhelekileyo kokungcamla. Ikwaxhasa ukuphiliswa kwenxeba, ukusebenza komzimba kunye nempilo yokuzala (1).

Abasemagunyeni kwezempilo babeke inqanaba lokutya elinyamezelwayo (i-UL) le-zinc kwi-40 mg ngosuku kubantu abadala. I-UL lelona xabiso liphezulu lemihla ngemihla lesondlo. Uninzi lwabantu alunakufane lubangelwe ziziphumo ebezingalindelekanga (1, 2).

Imithombo yokutya ephezulu kwi-zinc ibandakanya inyama ebomvu, iinkukhu, ukutya kwaselwandle, ukutya okuziinkozo kunye neenkozo eziqinileyo. Iimbatyisi ziqulathe elona xabiso liphezulu, ukuya kuthi ga kwi-493% yexabiso lemihla ngemihla kwi-3-ounce (85-gram) ekhonza (1).

Nangona okunye ukutya kunokubonelela ngezixa ngaphezulu kwe-UL, akukho zityholo zixeliweyo zetyhefu yeZinc evela kwizinc ngokwendalo (2).

Nangona kunjalo, ityhefu yeZink inokwenzeka kwizongezo zokutya, kubandakanya iivithamini, okanye ngenxa yokungeniswa ngengozi kweemveliso zekhaya eziqukethe izinc.

Nazi iimpawu ezi-7 eziqhelekileyo kunye neempawu zokugqithisa kwe-zinc.

1. Isicaphucaphu nokuHlanza

Isicaphucaphu nokugabha zixhaphakile iziphumo ebezingalindelekanga zetyhefu yeZinc.

Ukuphononongwa kwezifundo ezili-17 ekusebenzeni kwezongezelelo ze-zinc zokunyanga ukubanda okuqhelekileyo kufumanise ukuba i-zinc inokunciphisa ixesha lokubanda, kodwa iziphumo ezibi ziqhelekile. Ngapha koko, i-46% yabathathi-nxaxheba baxela isicaphucaphu ().

Iidosi ezingaphezulu kwe-225 mg zineemetic, oko kuthetha ukuba ukugabha kunokwenzeka kwaye kunokwenzeka ngokukhawuleza. Kwimeko enye, isicaphucaphu esomeleleyo kunye nokugabha kwaqala nje kwimizuzu engama-30 emva kwethamo elinye le-zinc le-570 mg (4,).

Nangona kunjalo, ukugabha kunokwenzeka ngeedosi ezisezantsi ngokunjalo. Kwisifundo esinye seeveki ezintandathu kubantu abangama-47 abasempilweni abathatha i-150 mg ye-zinc ngemini, ngaphezulu kwesiqingatha sokufumana isicaphucaphu kunye nokugabha ().

Nangona ukugabha kunokunceda ekupheliseni umzimba ngamanani ayityhefu e-zinc, kunokuba kungonelanga ukuthintela ezinye iingxaki.

Ukuba usebenzise inani elinetyhefu le-zinc, funa uncedo lwezonyango kwangoko.

Isicaphucaphu nokugabha kuqhelekile kwaye zihlala zisabela ngokukhawuleza ekungeniseni izixa ezinetyhefu ye-zinc.

2. Intlungu yesisu kunye nohudo

Ngokwesiqhelo, iintlungu zesisu kunye norhudo lwenzeka ngokudibeneyo nesicaphucaphu kunye nokugabha.

Kuphononongo olunye lwezifundo ezili-17 kwizongezo ze-zinc kunye nokubanda okuqhelekileyo, malunga ne-40% yabathathi-nxaxheba baxele iintlungu zesisu kunye norhudo ().

Nangona kunqabile kakhulu, ukukrala kwamathumbu kunye nokuphuma kwamathumbu esiswini kuye kwaxelwa.

Kwimeko enye, umntu ophuma emathunjini opha emva kokuthatha i-220 mg ye-zinc sulfate kabini ngemini kunyango lwe-acne ().

Ngapha koko, ukugxila kwe-zinc chloride enkulu kune-20% kuyaziwa ukuba kubangele umonakalo omkhulu kumazinyo esiswini (,).

I-zinc chloride ayisetyenziswanga kwizongezo zokutya, kodwa ityhefu inokwenzeka xa kungeniswe ngengozi iimveliso zekhaya. Izinto zokuncamathelisa, ukutywina, ukuhambisa amanzi, ukucoca iikhemikhali kunye neemveliso zokugqiba iinkuni zonke ziqukethe i-zinc chloride.

Intlungu yesisu kunye norhudo ziimpawu eziqhelekileyo zetyhefu yeZinc. Kwezinye iimeko, umonakalo omkhulu wesisu kunye nokuphuma kwegazi kunokwenzeka.

3. Iimpawu ezinjengomkhuhlane

Ukuthatha i-zinc ngaphezulu kune-UL esekwe kunokubangela iimpawu ezinje ngomkhuhlane, ezinje ngomkhuhlane, ukugodola, ukukhohlela, intloko ebuhlungu nokudinwa ().

Ezi mpawu zenzeka kwiimeko ezininzi, kubandakanya nezinye izinto ezinobuthi. Ke, ukuxilonga ityhefu yeZink kunokuba nzima.

Ugqirha wakho unokufuna imbali eneenkcukacha zonyango kunye nokutya, kunye nokuvavanywa kwegazi, kwisityholo esityholwayo samaminerali.

Ukuba uthatha izongezo, qiniseka ukuba uzityhila kumboneleli wakho wezempilo.

Iimpawu ezinje ngomkhuhlane zinokubakho ngenxa yeetyhefu zamaminerali aliqela, kubandakanya i-zinc. Ke, kubalulekile ukuba uxele zonke izongezo kumboneleli wakho wezempilo ukuqinisekisa unyango olululo.

4. Cholesterol yeHDL esezantsi "elungileyo"

“Okulungileyo” i-cholesterol ye-HDL yehlisa umngcipheko wesifo sentliziyo ngokususa i-cholesterol kwiiseli zakho, ngaloo ndlela kuthintelwe ukwakhiwa kwe-plaque evala umthambo.

Kubantu abadala, abasemagunyeni kwezempilo bacebisa i-HDL engaphezulu kwama-40 mg / dL. Amanqanaba asezantsi akubeka kumngcipheko ophezulu wesifo sentliziyo.

Uphengululo lwezifundo ezininzi kumanqanaba e-zinc kunye ne-cholesterol iphakamisa ukuba ukongeza ngaphezulu kwe-50 mg ye-zinc ngemini kunokuhlisa amanqanaba akho "amahle" e-HDL kwaye kungabinampembelelo kwi-cholesterol yakho "embi" ye-LDL (,,).

Uphengululo lukwatsho ukuba idosi ye-30 mg ye-zinc ngosuku-engaphantsi kwe-UL ye-zinc-ayinaziphumo kwi-HDL xa ithathwa ukuya kuthi ga kwiiveki ezili-14 ().

Ngelixa izinto ezininzi zichaphazela amanqanaba e-cholesterol, ezi ziphumo ziyinto ekufuneka uyiqwalasele ukuba uthatha izongezo ze-zinc rhoqo.

Ukungenisa rhoqo i-zinc ngaphezulu kwamanqanaba acetyiswayo kunokubangela ukwehla kwamanqanaba e-cholesterol e-HDL "anokukubeka emngciphekweni omkhulu wesifo sentliziyo.

5. Utshintsho kwiTaste yakho

I-Zinc ibalulekile kulwazi lwakho lokungcamla. Ngapha koko, ukunqongophala kwe-zinc kunokubangela imeko ebizwa ngokuba yi-hypogeusia, ukungasebenzi kakuhle kwikhono lakho lokungcamla (1).

Into enomdla kukuba, i-zinc engaphezulu kwamanqanaba acetyiswayo inokubangela notshintsho lwencasa, kubandakanya incasa embi okanye yentsimbi emlonyeni wakho.

Ngokwesiqhelo, olu phawu luxelwa kwizifundo eziphanda i-zinc lozenges (amathontsi okhohlela) okanye izongezo zolwelo ekunyangeni umkhuhlane oqhelekileyo.

Ngelixa ezinye izifundo zichaza iziphumo eziluncedo, iidosi ezisetyenzisiweyo zihlala ngaphezulu kwe-UL ye-40 mg ngosuku, kwaye iziphumo ezibi ziqhelekile ().

Umzekelo, i-14% yabathathi-nxaxheba kwisifundo seveki enye bakhalaza ngokungalunganga kokungcamla emva kokunyibilika kwe-25-mg zinc zinc emilonyeni yabo rhoqo emva kweeyure ezimbini ngelixa bevukile ().

Kwesinye isifundo kusetyenziswa isongezelelo kulwelo, ama-53% abathathi-nxaxheba baxele incasa yentsimbi. Nangona kunjalo, akucaci ukuba ezi mpawu zihlala ixesha elingakanani ().

Ukuba usebenzisa i-lozenji ye-zinc okanye izongezo zolwelo, yazi ukuba ezi mpawu zinokwenzeka nokuba imveliso ithathwa njengoko kuyalelwe (16).

IZinc idlala indima ekuboneni incasa. Ukugqithisa i-zinc kunokubangela incasa yesinyithi emlonyeni wakho, ngakumbi ukuba ithathwa njenge-lozenge okanye isongezo samanzi.

6. Ukusilela kweCopper

I-Zinc kunye nobhedu bancintisana nokufunxwa emathunjini akho amancinci.

Iidosi ze-zinc ngaphezulu kwe-UL esekwe zinokuphazamisa amandla omzimba wakho wokufumana ubhedu. Ixesha elingaphezulu, oku kunokubangela ukunqongophala kobhedu (2).

Njenge-zinc, ubhedu sisimbiwa esifanelekileyo. Inceda ekufunxeni isinyithi kunye imetabolism, isenza ukuba kube yimfuneko ukuyilwa kweeseli ezibomvu zegazi. Ikwadlala indima ekwakhiweni kweeseli ezimhlophe zegazi ().

Iiseli ezibomvu zegazi zihambisa ioksijini ngomzimba wakho, ngelixa iiseli ezimhlophe zegazi zibadlala indima ephambili kumzimba wakho wokuzikhusela.

Ukunqongophala kobhedu okubangelwa yi-Zinc kunxulunyaniswa nokuphazamiseka kwegazi (,,):

• I-anemia yentswelo: Ukunqongophala kweeseli ezibomvu ezisempilweni ngenxa yokunganeli kwesixa emzimbeni wakho.
• I-anideroblastic anemia: Ukunqongophala kweeseli ezibomvu ezisempilweni ngenxa yokungakwazi ukwenza isinyithi ngokufanelekileyo.
• Neutropenia: Ukunqongophala kweeseli ezimhlophe ezisempilweni ngenxa yokuphazamiseka ekubunjweni kwazo.

Ukuba unentswelo yobhedu, sukuxuba izongezo zethusi kunye ne-zinc.

Amanqanaba aqhelekileyo e-zinc ngaphezulu kwe-40 mg ngosuku anokuthintela ukufunxwa kobhedu. Oku kunokubangela ukunqongophala kobhedu, okunxulunyaniswa nokuphazamiseka kwegazi okuninzi.

7. Izifo ezenzeka rhoqo

Nangona i-zinc idlala indima ebalulekileyo ekusebenzeni kwamajoni omzimba, i-zinc eninzi inokucinezela impendulo yakho yomzimba ().

Oku kuhlala kuyimpembelelo ye-anemias kunye ne-neutropenia, kodwa ikwabonakalisiwe ukuba iyenzeka ngaphandle kokuphazamiseka kwegazi okubangelwa zinc.

Kwizifundo zetyhubhu yovavanyo, i-zinc egqithisileyo inciphise ukusebenza kweeseli ze-T, uhlobo lweseli emhlophe yegazi. Iiseli ze-T zidlala indima ephambili ekuphenduleni komzimba wakho ngokuncamathisela kunye nokutshabalalisa ii-pathogen eziyingozi (,,).

Izifundo zabantu ziyayixhasa le nto, kodwa iziphumo azihambelani.

Isifundo esincinci kwindoda eyi-11 esempilweni yafumana isinciphiso sokuphendula komzimba emva kokuba ifake i-150 mg ye-zinc kabini ngemini iiveki ezintandathu ().

Nangona kunjalo, ukongeza nge-110 mg ye-zinc kathathu ngemini kwinyanga enye yayineziphumo ezixubileyo kubantu abadala. Abanye banamava okuphungulwa kwempendulo yomzimba, ngelixa abanye benempendulo eyandisiweyo ().

Ukuthatha izongezo ze-zinc kwiidosi ezingaphezulu kwe-UL kunokucinezela impendulo yakho yomzimba, kukushiya usengozini yokugula kunye nosulelo.

Ukhetho kunyango

Ukuba uyakholelwa ukuba unokufumana ityhefu ye-zinc, nxibelelana neziko lakho lolawulo lwetyhefu kwangoko.

Ityhefu yeZinc isongela ubomi. Ke ngoko, kubalulekile ukuba ufune uncedo lwezonyango kwangoko.

Unokucetyiswa ukuba usele ubisi, njengoko amaxabiso aphezulu e-calcium kunye ne-phosphorus kuwo anokunceda ekuthinteleni ukufunxwa kwe-zinc kwiphecana lesisu. Amalahle avuselelweyo anempembelelo efanayo ().

Iiarhente ezichasayo zikwasetyenzisiwe kwiimeko ezinobungozi. Oku kunceda ukususa umzimba kwi-zinc egqithileyo ngokuyibophelela egazini. Emva koko iyagxothwa kumchamo wakho, endaweni yokungena kwiiseli zakho.

Ityhefu yeZinc yimeko esongela ubomi. Kubalulekile ukufuna uncedo lwezonyango ngokukhawuleza.

Umgca osezantsi

Nangona okunye ukutya kuqulethe i-zinc ngaphezulu kwe-UL ye-40 mg ngosuku, akukho matyala enetyhefu evela kwi-zinc evela kwindalo ekutyeni athe axelwa.

Nangona kunjalo, i-zinc overdose inokwenzeka kwizongezo zokutya okanye ngenxa yokungenisa ngengozi.

I-Zinc ityhefu inokuba neziphumo ezibi kunye nezingapheliyo. Ubungqongqo beempawu zakho ubukhulu becala buxhomekeke kwidosi kunye nexesha lokutya.

Ngokungenisa ngokukhawuleza iidosi eziphezulu ze-zinc, iimpawu zesisu zinokwenzeka. Kwiimeko ezinzima, njengokungena ngengozi kweemveliso zekhaya eziqukethe i-zinc, ukubola kwamathumbu kunye nokopha.

Ukusetyenziswa kwexesha elide kunokubangela iziphumo ebezingalindelekanga kodwa ezinobuzaza, ezinje nge-cholesterol elungileyo "elungileyo" ye-HDL, ukunqongophala kobhedu kunye nenkqubo yomzimba yokucinezela.

Ngokubanzi, kuya kufuneka ugqithe kwi-UL esekwe phantsi kolawulo lweengcali zonyango.